Alzheimer’s disease-specific transcriptomic and epigenomic changes in the tryptophan catabolic pathway

Autor: Kyonghwan Choe, Muhammad Ali, Roy Lardenoije, Renzo J.M. Riemens, Ehsan Pishva, Horst Bickel, Siegfried Weyerer, Per Hoffmann, Michael Pentzek, Steffi Riedel-Heller, Birgitt Wiese, Martin Scherer, Michael Wagner, Diego Mastroeni, Paul D. Coleman, Alfredo Ramirez, Inez H.G.B. Ramakers, Frans R.J. Verhey, Bart P.F. Rutten, Gunter Kenis, Daniel L.A. van den Hove

Publikováno v: Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)

Abstract Background Neurodegenerative disorders, including Alzheimer’s disease (AD), have been linked to alterations in tryptophan (TRP) metabolism. However, no studies to date have systematically explored changes in the TRP pathway at both transcr

Externí odkaz: https://doaj.org/article/d7f42511bb034992821e597dec5d1cd1

Alzheimer's disease-specific transcriptomic and epigenomic changes in the tryptophan catabolic pathway.

Autor: Choe, Kyonghwan¹ (AUTHOR), Ali, Muhammad^1,2,3 (AUTHOR), Lardenoije, Roy^1,4 (AUTHOR), Riemens, Renzo J.M.¹ (AUTHOR), Pishva, Ehsan^1,5 (AUTHOR), Bickel, Horst⁶ (AUTHOR), Weyerer, Siegfried⁷ (AUTHOR), Hoffmann, Per^8,9,10 (AUTHOR), Pentzek, Michael¹¹ (AUTHOR), Riedel-Heller, Steffi¹² (AUTHOR), Wiese, Birgitt¹³ (AUTHOR), Scherer, Martin¹⁴ (AUTHOR), Wagner, Michael^15,16 (AUTHOR), Mastroeni, Diego^1,17,18 (AUTHOR), Coleman, Paul D.¹⁸ (AUTHOR), Ramirez, Alfredo^{15,16,19,20,21} (AUTHOR), Ramakers, Inez H.G.B.^1,22 (AUTHOR), Verhey, Frans R.J.^1,22 (AUTHOR), Rutten, Bart P.F.¹ (AUTHOR), Kenis, Gunter¹ (AUTHOR)

Publikováno v: Alzheimer's Research & Therapy. 11/30/2024, Vol. 16 Issue 1, p1-16. 16p.

Studies in the Area of Alzheimer Disease Reported from Maastricht University (Alzheimer's disease-specific transcriptomic and epigenomic changes in the tryptophan catabolic pathway).

Publikováno v: Genomics & Genetics Weekly; 12/20/2024, p1752-1752, 1p