Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Renzo G DiNatale"'
Autor:
Andrea Knezevic, Yasser Ged, Joshua L Chaim, Renzo G DiNatale, Ritesh R Kotecha, Maria I Carlo, Chung-Han Lee, Ashley Foster, Darren R Feldman, Min Yuen Teo, Gopakumar Iyer, Timothy Chan, A Ari Hakimi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Loss-of-function alterations in DNA damage repair (DDR) genes are associated with human tumorigenesis and may determine benefit from immune-oncology (I/O) agents as shown in colon cancer. However, biologic significance and relevance to I/O
Externí odkaz:
https://doaj.org/article/256aee4f74274772a16f55b728dc15b9
Autor:
A. Ari Hakimi, Kyrollis Attalla, Renzo G. DiNatale, Irina Ostrovnaya, Jessica Flynn, Kyle A. Blum, Yasser Ged, Douglas Hoen, Sviatoslav M. Kendall, Ed Reznik, Anita Bowman, Jason Hwee, Christopher J. Fong, Fengshen Kuo, Martin H. Voss, Timothy A. Chan, Robert J. Motzer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The clinical benefit from immunotherapy response in patients with mutations of genes forming the chromatin remodelling complex PBAF remains controversial. Here the authors show that PBAF complex mutations are not associated with favourable response i
Externí odkaz:
https://doaj.org/article/655ac0280dd44b29884b0203c1be1bd4
Autor:
Andrew W. Silagy, Amy L. Tin, Phillip Rappold, Emily A. Vertosick, Roy Mano, Kyrollis Attalla, Angela Yoo, Stanley Weng, Renzo G. DiNatale, Andrew J. Vickers, Daniel D. Sjoberg, Jonathan A. Coleman, Paul Russo, Abraham Ari Hakimi
Publikováno v:
Clinical Genitourinary Cancer. 20:e432-e439
In systemic therapy trials, a decreasing neutrophil-to-lymphocyte ratio (NLR) after treatment for metastatic renal cell carcinoma (RCC) has been associated with improved oncologic outcomes. Paradoxically, for patients with localized RCC treated with
Publikováno v:
Urology. 167:24-29
To assess the national case logs of the first graduating urologic resident cohorts to have trained during the COVID-19 pandemic for effects on surgical volumes.The nationally aggregated Accreditation Council for Graduate Medical Education urology res
Autor:
Nathan Jung, Renzo G. DiNatale, Jason Frankel, Hannah Koenig, On Ho, John Paul Flores, Christopher Porter
Publikováno v:
World Journal of Urology. 41:663-671
Transrectal ultrasound (US) imaging is paramount to the successful completion of prostate biopsies. Certain US features have been associated with prostate cancer (PCa), but their utility remains controversial. We explored the role of multiparametric
Autor:
Phillip M. Rappold, Lynda Vuong, Josef Leibold, Nicholas H. Chakiryan, Michael Curry, Fengshen Kuo, Erich Sabio, Hui Jiang, Briana G. Nixon, Ming Liu, Anders E. Berglund, Andrew W. Silagy, Eduardo A. Mascareno, Mahdi Golkaram, Mahtab Marker, Albert Reising, Alexander Savchenko, John Millholland, Ying-Bei Chen, Paul Russo, Jonathan Coleman, Ed Reznik, Brandon J. Manley, Irina Ostrovnaya, Vladimir Makarov, Renzo G. DiNatale, Kyle A. Blum, Xiaoxiao Ma, Diego Chowell, Ming O. Li, David B. Solit, Scott W. Lowe, Timothy A. Chan, Robert J. Motzer, Martin H. Voss, A. Ari Hakimi
Publikováno v:
Cancer Discov
It is poorly understood how the tumor immune microenvironment influences disease recurrence in localized clear-cell renal cell carcinoma (ccRCC). Here we performed whole-transcriptomic profiling of 236 tumors from patients assigned to the placebo-onl
Autor:
A. Ari Hakimi, Martin H. Voss, Robert J. Motzer, Timothy A. Chan, Scott W. Lowe, David B. Solit, Ming O. Li, Diego Chowell, Xiaoxiao Ma, Kyle A. Blum, Renzo G. DiNatale, Vladimir Makarov, Irina Ostrovnaya, Brandon J. Manley, Ed Reznik, Jonathan Coleman, Paul Russo, Ying-Bei Chen, John Millholland, Alexander Savchenko, Albert Reising, Mahtab Marker, Mahdi Golkaram, Eduardo A. Mascareno, Andrew W. Silagy, Anders E. Berglund, Ming Liu, Briana G. Nixon, Hui Jiang, Erich Sabio, Fengshen Kuo, Michael Curry, Nicholas H. Chakiryan, Josef Leibold, Lynda Vuong, Phillip M. Rappold
It is poorly understood how the tumor immune microenvironment influences disease recurrence in localized clear-cell renal cell carcinoma (ccRCC). Here we performed whole-transcriptomic profiling of 236 tumors from patients assigned to the placebo-onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af22d74b1526aba432a0f069b99d41d9
https://doi.org/10.1158/2159-8290.c.6549733.v1
https://doi.org/10.1158/2159-8290.c.6549733.v1
Autor:
A. Ari Hakimi, Martin H. Voss, Robert J. Motzer, Timothy A. Chan, Scott W. Lowe, David B. Solit, Ming O. Li, Diego Chowell, Xiaoxiao Ma, Kyle A. Blum, Renzo G. DiNatale, Vladimir Makarov, Irina Ostrovnaya, Brandon J. Manley, Ed Reznik, Jonathan Coleman, Paul Russo, Ying-Bei Chen, John Millholland, Alexander Savchenko, Albert Reising, Mahtab Marker, Mahdi Golkaram, Eduardo A. Mascareno, Andrew W. Silagy, Anders E. Berglund, Ming Liu, Briana G. Nixon, Hui Jiang, Erich Sabio, Fengshen Kuo, Michael Curry, Nicholas H. Chakiryan, Josef Leibold, Lynda Vuong, Phillip M. Rappold
Supplementary Figure from A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1ec763b13cff9a6658602529674209
https://doi.org/10.1158/2159-8290.22541734.v1
https://doi.org/10.1158/2159-8290.22541734.v1
Autor:
Timothy A. Chan, Robert J. Motzer, A. Ari Hakimi, Kenichi Nomoto, Yasuhiro Funahashi, Junji Matsui, Yukinori Minoshima, Yusuke Adachi, Pallavi Sachdev, Darren Feldman, Maria I. Carlo, Martin H. Voss, Ritesh Kotecha, Samuel Murray, Ed Reznik, Luc Morris, Doug Hoen, Kate Weiss, Mark Lee, Lynda Vuong, Cristina Valero, Vladimir Makarov, Chirag Krishna, Diego Chowell, Renzo G. DiNatale, Chung-Han Lee
Immune checkpoint blockade (ICB) therapy has substantially improved the outcomes of patients with many types of cancers, including renal cell carcinoma (RCC). Initially studied as monotherapy, immunotherapy-based combination regimens have improved th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0dc734be5d9dd693e64ffcaa2e3da3
https://doi.org/10.1158/1541-7786.c.6545243.v1
https://doi.org/10.1158/1541-7786.c.6545243.v1
Autor:
Timothy A. Chan, Robert J. Motzer, A. Ari Hakimi, Kenichi Nomoto, Yasuhiro Funahashi, Junji Matsui, Yukinori Minoshima, Yusuke Adachi, Pallavi Sachdev, Darren Feldman, Maria I. Carlo, Martin H. Voss, Ritesh Kotecha, Samuel Murray, Ed Reznik, Luc Morris, Doug Hoen, Kate Weiss, Mark Lee, Lynda Vuong, Cristina Valero, Vladimir Makarov, Chirag Krishna, Diego Chowell, Renzo G. DiNatale, Chung-Han Lee
HLA class-I allele data along with mean HED values for the lenvatinib/pembrolizumab and MSK-IMPACT cohorts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e73d0d1f26fdffbd276973c64e2ff13
https://doi.org/10.1158/1541-7786.22526897.v1
https://doi.org/10.1158/1541-7786.22526897.v1