Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Renzhong Lu"'
Publikováno v:
Cells, Vol 12, Iss 24, p 2775 (2023)
In this study, we reported that novel single-chain fusion proteins linking thromboxane A2 (TXA2) receptor (TP) to a selected G-protein α-subunit q (SC-TP-Gαq) or to α-subunit s (SC-TP-Gαs) could be stably expressed in megakaryocytes (MKs). We tes
Externí odkaz:
https://doaj.org/article/d586def9c02b49318bfa93dcc277c19c
Publikováno v:
Future Medicinal Chemistry. 15:757-767
Aim: The objective of this study was to synthesize and validate a set of compounds that selectively inhibit mPGES-1, with the potential to be developed into a novel anti-inflammatory drug. Methods: The synthesized compounds were characterized using 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b6e65f5ce5b37a16983ae657f29bcb2
https://doi.org/10.4155/fmc-2023-0039
https://doi.org/10.4155/fmc-2023-0039
Publikováno v:
Future Medicinal Chemistry. 13:765-768
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d500d0ff32afb50cd595dd9b42552e67
https://doi.org/10.4155/fmc-2020-0340
https://doi.org/10.4155/fmc-2020-0340
Publikováno v:
Future Med Chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becd450cf7ff8e1e5286cd17e7fa7f33
https://europepmc.org/articles/PMC8905551/
https://europepmc.org/articles/PMC8905551/
Publikováno v:
Future Med Chem
Aim: This study investigated our Enzymelinks, COX-2-10aa-mPGES-1 and COX-2-10aa-PGIS, as cellular cross-screening targets for quick identification of lead compounds to inhibit inflammatory PGE2 biosynthesis while maintaining prostacyclin synthesis. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86abef784c1e42edc4d909d5aa4ddcd3
https://pubmed.ncbi.nlm.nih.gov/34080888
https://pubmed.ncbi.nlm.nih.gov/34080888
Publikováno v:
Biochemical Engineering Journal. 184:108465
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b338a6b32f18da4b7cdeec1b47b8914a
https://doi.org/10.1016/j.bej.2022.108465
https://doi.org/10.1016/j.bej.2022.108465
Publikováno v:
Future medicinal chemistry. 13(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ad61265c567046c362f2d50258c24a3
https://pubmed.ncbi.nlm.nih.gov/33759567
https://pubmed.ncbi.nlm.nih.gov/33759567
Autor:
Yinhui Zeng, MD, Qingxiang Zeng, MD, PhD, Yueqiang Wen, MD, PhD, Jinyuan Li, MD, Haiqing Xiao, MD, Chao Yang, MD, Renzhong Luo, MD, Wenlong Liu, MD, PhD
Publikováno v:
Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 2, Pp 100212- (2024)
Background: Group 2 innate lymphoid cells (ILC2s) have been found to take part in type 2 inflammation by secreting TH2 cytokines. Apolipoprotein A-I (Apo-AI), a major structural and functional protein of high-density lipoproteins, has anti-inflammato
Externí odkaz:
https://doaj.org/article/123e57aabd2743f198dbde45961d40ba
Autor:
Wanqi Yang, Renzhong Lu, Jiaqi Liu, Zhiguo Wang, Zhimin Du, Zhenwei Pan, Hongwen Xiao, Yuying Wang, Haixia Zhu, Yue Zhang, Yuting Zhuang, Fei Sun, Yanjie Lu
Publikováno v:
Oncotarget
microRNA-16 (miR-16) has been shown to be up-regulated in ischemic heart. Beta2-adrenoreceptor (β2-AR) exerts cardioprotective property in ischemic injury. This study aims to determine the effect of miR-16 in cardiac injury in rats and the possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845119c6e7a7f1a5e73bdcbf39ce7ef0
http://europepmc.org/articles/PMC5386749
http://europepmc.org/articles/PMC5386749
Autor:
Xin Zhou, Guiye Zhang, You Shu, Ti Yang, Ming Gao, Wei Zhao, Shenjian Luo, Yanan Zhuang, Renzhong Lu, Fei Sun, Wei Mu, Yanjie Lu, Chaoqian Xu, Fengzhi Ding
Publikováno v:
International Journal of Biological Sciences
Background: MicroRNAs (miRNAs) have been emerged as important regulator in a multiple of cardiovascular disease, including arrhythmia, cardiac hypertrophy and fibrosis, and myocardial infarction. The aim of this study was to investigate whether miRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe67437c25670fb36837c7447fc70ee3
http://europepmc.org/articles/PMC5264258
http://europepmc.org/articles/PMC5264258