Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Renyikun Yuan"'
Autor:
Baolin Wang, Qinqin Wang, Renyikun Yuan, Shilin Yang, Meilin Lu, Fuhong Yuan, Zhidan Dong, Menghuan Mo, Qiming Pan, Hongwei Gao
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Background The successful launch of icaritin, a therapeutic drug for liver cancer derived from Epimedium brevicornu, has provided new impetus for the development of prenylated flavonoids in the field of oncology. Flemingia macrophylla is rep
Externí odkaz:
https://doaj.org/article/698c1c429a274f9e9d8639fd61e987d0
Autor:
Kaili Sun, Renyikun Yuan, Jia He, Youqiong Zhuo, Ming Yang, Erwei Hao, Xiaotao Hou, Chun Yao, Shilin Yang, Hongwei Gao
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21889- (2023)
Background: Necroptosis, a novel form of programmed cell death wherein the necrotic morphology is characterized by swelling of the cells, rupture of the plasma membrane, and dysfunction of the organelle, has been always observed in cardiovascular dis
Externí odkaz:
https://doaj.org/article/924badfe06e74649af0dcaed4dc960ab
Autor:
Xiaowei Liang, Hongwei Gao, Jian Xiao, Shan Han, Jia He, Renyikun Yuan, Shilin Yang, Chun Yao
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundIndoleamine-2,3-dioxygenase 1 (IDO1) is responsible for tumor immune escape by regulating T cell-associated immune responses and promoting the activation of immunosuppressive. Given the vital role of IDO1 in immune response, further investi
Externí odkaz:
https://doaj.org/article/3c76156ed672481999897ab03add5316
Autor:
Siyuan Li, Renyikun Yuan, Qiumei Fan, Chunting Zhang, Shan Han, Jilang Li, Zhipeng Xu, Kaili Sun, Qiongming Xu, Chun Yao, Shilin Yang, Hongwei Gao
Publikováno v:
Journal of Functional Foods, Vol 102, Iss , Pp 105475- (2023)
Ginsenoside Rb1 (GRb1), a bioactive ingredient of Panax ginseng C. A. Meyer, has the effects of anti-tumor, anti-inflammation, and cardiovascular protection. The present study aims to explore the effects and potential mechanisms of GRb1 on UC. GRb1 s
Externí odkaz:
https://doaj.org/article/d25a7ac2999046988bfbedcaecfbfb02
Autor:
Renyikun Yuan, Qiumei Fan, Xiaowei Liang, Shan Han, Jia He, Qin-Qin Wang, Hongwei Gao, Yulin Feng, Shilin Yang
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-16 (2022)
Abstract Background Lung cancer is the leading cause of cancer mortality worldwide, and most of the patients after treatment with EGF-TKIs develop drug resistance, which is closely correlated with EMT. Cucurbitacin B (CuB) is a natural product of the
Externí odkaz:
https://doaj.org/article/0726c7d716574f42a62cf122bf0070c1
Autor:
Renyikun Yuan, Yuqing Li, Shan Han, Xinxin Chen, Jingqi Chen, Jia He, Hongwei Gao, Yang Yang, Shilin Yang, Yu Yang
Publikováno v:
ACS Central Science, Vol 8, Iss 1, Pp 10-21 (2021)
Externí odkaz:
https://doaj.org/article/b86b249a59f54297959c2e34e4475d0a
Autor:
Dongjie Zhang, Renyikun Yuan, Jiaping Pan, Qiumei Fan, Kaili Sun, Zhipeng Xu, Xiang Gao, Qinqin Wang, Jia He, Yaqing Ye, Zhengrong Mu, Jing Leng, Hongwei Gao
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 11953 (2023)
Lung cancer is one of the leading causes of cancer death. Non-small-cell lung cancer (NSCLC) accounts for the majority of lung cancer diagnoses. Dihydrotanshinone (DHT) is a compound extract from Salvia miltiorrhiza, which has favorable anti-inflamma
Externí odkaz:
https://doaj.org/article/11cb1b7002c44cd8a88c0846511bb98b
Autor:
Youqiong Zhuo, Renyikun Yuan, Xinxin Chen, Jia He, Yangling Chen, Chenwei Zhang, Kaili Sun, Shilin Yang, Zhenjie Liu, Hongwei Gao
Publikováno v:
Chinese Medicine, Vol 16, Iss 1, Pp 1-15 (2021)
Abstract Background Tanshinone I (TI) is a primary component of Salvia miltiorrhiza Bunge (Danshen), which confers a favorable role in a variety of pharmacological activities including cardiovascular protection. However, the exact mechanism of the ca
Externí odkaz:
https://doaj.org/article/21aa3805aab1455483d67bab35e40a77
Autor:
Yangling Chen, Rui Chen, Renyikun Yuan, Lini Huo, Hongwei Gao, Youqiong Zhuo, Xinxin Chen, Chenwei Zhang, Shilin Yang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3575 (2023)
NF-κB and MAPK are classic inflammation signaling pathways which regulate inflammation signal transmission and induce the expression of many inflammatory factors. Based on the potent anti-inflammatory activity of benzofuran and its derivatives, seve
Externí odkaz:
https://doaj.org/article/27ac57767e474710923cbd8fedd3c5c5
Autor:
Shan Han, Renyikun Yuan, Yushun Cui, Jia He, Qin-Qin Wang, Youqiong Zhuo, Shilin Yang, Hongwei Gao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Gene transcription is governed by epigenetic regulation that is essential for the pro-inflammatory mediators surge following pathological triggers. Acute lung injury (ALI) is driven by pro-inflammatory cytokines produced by the innate immune system,
Externí odkaz:
https://doaj.org/article/156db67556154113a720db743257bb41