Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Renuka, Sivendran"'
Publikováno v:
Immunotherapy. 10(11)
Analytical similarity is the foundation of the totality-of-evidence-based approach for demonstrating that a proposed biosimilar is highly similar to a reference product. This review uses analytical similarity assessment of ABP 501, the first approved
Publikováno v:
Biochemical Society Symposia. 68:69-82
Members of the Hsp70 (heat-shock protein of 70 kDa) family of molecular chaperones bind to exposed hydrophobic stretches on substrate proteins in order to dissociate molecular complexes and prevent aggregation in the cell. Substrate affinity for the
Autor:
Gizem Dinler, Mathias Stotz, Renuka Sivendran, Lila M. Gierasch, Diana L. Montgomery, Joanna F. Swain
Hsp70 chaperones assist in protein folding, disaggregation, and membrane translocation by binding to substrate proteins with an ATP-regulated affinity that relies on allosteric coupling between ATP-binding and substrate-binding domains. We have studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9fe73282306dcb2ae7e54e75b8478f
https://europepmc.org/articles/PMC1894942/
https://europepmc.org/articles/PMC1894942/
Autor:
Renuka Sivendran, Jeffrey L. Brodsky, Mark D. Rose, Michael W. Morrow, Lila M. Gierasch, Stephanie S. Kelley, Mehdi Kabani, Diana L. Montgomery
Publikováno v:
Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2003, 14 (8), pp.3437-3448. ⟨10.1091/mbc.e02-12-0847⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2003, 14 (8), pp.3437-3448. ⟨10.1091/mbc.e02-12-0847⟩
International audience; ER-associated degradation (ERAD) removes defective and mis-folded proteins from the eukary-otic secretory pathway, but mutations in the ER lumenal Hsp70, BiP/Kar2p, compromise ERAD efficiency in yeast. Because attenuation of E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77b4750d7a5b3871c564817e759d306
https://hal.archives-ouvertes.fr/hal-02989532
https://hal.archives-ouvertes.fr/hal-02989532
Autor:
William G. Stetler-Stevenson, Renuka Sivendran, Hongmei Li, Tere Diaz, Dong-Wan Seo, Beiyang Wei
Publikováno v:
Cancer Research. 68:LB-332
The vascular endothelial growth factors (VEGFs) and their receptors (receptor tyrosine kinases) are critical for angiogenesis. The binding of VEGF-A induces dimerization and autophosphorylation of its receptor, VEGFR-2. This initiates a signaling cas
Autor:
Mehdi, Kabani, S, Kelley Stephanie, W, Morrow Michael, L, Montgomery Diana, Renuka, Sivendran, D, Rose Mark, M, Gierasch Lila, L, Brodsky Jeffrey
Publikováno v:
Molecular Biology of the Cell; August 2003, Vol. 14 Issue: 8 p3437-48, 12p