Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Renty B. Franklin"'
Autor:
Leslie C. Costello, Renty B. Franklin
Publikováno v:
Oncology Reviews, Vol 12, Iss 2 (2018)
Hormone-independent malignancy is a major issue of morbidity and deaths that confronts prostate cancer. Despite decades of research, the oncogenic and hormonal implications in the development and progression of prostate malignancy remain mostly specu
Externí odkaz:
https://doaj.org/article/1b146174d0034e808f2ec45e8ed49a8b
Publikováno v:
Dental Oral Biology and Craniofacial Research. :1-3
Laryngeal and tongue squamous cell carcinomas account for an estimated 37,000 cases and 7,000 deaths/year in the U.S. The localized lesions are generally treated by surgical resection, and/or radiation therapy. When progression to metastases occurs,
Autor:
Leslie C. Costello, Renty B. Franklin
Publikováno v:
Acta Sci Cancer Biol
Evidence is evolving that support the relationship that all carcinomas exhibit the following important relationships: The malignant cells exhibit a significant decreased zinc compared to the normal cells. The higher zinc levels that exist in the norm
Autor:
Renty B. Franklin, Linda T. Senbanjo, Meenakshi A. Chellaiah, Sunipa Majumdar, Deepa Srinivasan
Publikováno v:
Journal of Cellular Biochemistry
Studies have shown that a subgroup of tumor cells possess stemness characteristics having self‐renewal capacity and the ability to form new tumors. We sought to identify the plausible stemness factor that determines the “molecular signature” of
Publikováno v:
Madridge journal of dentistry and oral surgery
High citrate concentration is a major component in the structure of craniofacial bone, teeth and periodontal tissues of humans and other osteovertebrates. It is now established that citrate incorporation into the apatite/collagen complex of bone is e
Autor:
Renty B. Franklin, Leslie C. Costello
Publikováno v:
Journal of liver research, disorders & therapy
Reported studies more than forty years ago established that all surgery patients exhibit a marked postoperative hypocitricemia within one day following surgery and persists for seven days and longer. Animals also exhibit the postoperative hypocitrice
Publikováno v:
Mathews journal of case reports. 4(1)
INTRODUCTION: Testosterone promotes the initial development of androgen-dependent prostate cancer. This is the basis for androgen ablation treatment, which attenuates, but does not terminate, the malignancy. Instead, it leads to prolactin-dependent m
Autor:
Renty B. Franklin, Leslie C. Costello
Publikováno v:
Human Endocrinology. 1:1-8
The homeostatic maintenance of a normal plasma citrate concentration is an important factor in humans and in animals; and is required for many normal physiological activities. Dysregulation of normal plasma citrate presents pathophysiological hypocit
Autor:
Leslie C. Costello, Renty B. Franklin
Publikováno v:
Expert Opinion on Therapeutic Targets. 21:51-66
Efficacious chemotherapy does not exist for treatment or prevention of prostate, liver, and pancreatic carcinomas, and some other cancers that exhibit decreased zinc in malignancy. Zinc treatment offers a potential solution; but its support has been
Publikováno v:
Cancer Causes & Control. 27:729-735
Altered zinc levels in malignant cells versus their normal cells have important implications in the development and progression of several cancers. Prostate, pancreatic, and hepatocellular carcinomas exhibit consistent marked zinc decrease in situ in