Defining mitochondrial protein functions through deep multiomic profiling.

Autor: Rensvold JW; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.; Morgridge Institute for Research, Madison, WI, USA., Shishkova E; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Sverchkov Y; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA., Miller IJ; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Cetinkaya A; Department of Medical Genetics, Faculty of Medicine, Hacettepe University, Ankara, Turkey., Pyle A; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Manicki M; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA.; Morgridge Institute for Research, Madison, WI, USA., Brademan DR; Morgridge Institute for Research, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA.; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Alanay Y; Department of Pediatrics, Pediatric Genetics Unit, Faculty of Medicine, Hacettepe University, Ankara, Turkey.; Department of Pediatrics, Pediatric Genetics Unit, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey., Raiman J; Department of Clinical Inherited Metabolic Disorders, Birmingham Women's and Children's Hospital NHS Trust, Birmingham, UK., Jochem A; Morgridge Institute for Research, Madison, WI, USA., Hutchins PD; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Peters SR; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Linke V; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Overmyer KA; Morgridge Institute for Research, Madison, WI, USA.; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Salome AZ; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Hebert AS; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Vincent CE; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Kwiecien NW; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Rush MJP; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Westphall MS; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Craven M; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA., Akarsu NA; Department of Medical Genetics, Faculty of Medicine, Hacettepe University, Ankara, Turkey., Taylor RW; Wellcome Centre for Mitochondrial Research, Newcastle University, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; NHS Highly Specialised Services for Rare Mitochondrial Disorders, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Coon JJ; Morgridge Institute for Research, Madison, WI, USA. jcoon@chem.wisc.edu.; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA. jcoon@chem.wisc.edu.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA. jcoon@chem.wisc.edu.; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA. jcoon@chem.wisc.edu., Pagliarini DJ; Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; Morgridge Institute for Research, Madison, WI, USA. pagliarini@wustl.edu.; National Center for Quantitative Biology of Complex Systems, Madison, WI, USA. pagliarini@wustl.edu.; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA. pagliarini@wustl.edu.; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA. pagliarini@wustl.edu.

Publikováno v: Nature [Nature] 2022 Jun; Vol. 606 (7913), pp. 382-388. Date of Electronic Publication: 2022 May 25.

Identification and Quantification of Murine Mitochondrial Proteoforms Using an Integrated Top-Down and Intact-Mass Strategy.

Autor: Schaffer LV, Rensvold JW; Morgridge Institute for Research , Madison , Wisconsin 53715 , United States., Shortreed MR, Cesnik AJ, Jochem A; Morgridge Institute for Research , Madison , Wisconsin 53715 , United States., Scalf M, Frey BL, Pagliarini DJ; Morgridge Institute for Research , Madison , Wisconsin 53715 , United States., Smith LM

Publikováno v: Journal of proteome research [J Proteome Res] 2018 Oct 05; Vol. 17 (10), pp. 3526-3536. Date of Electronic Publication: 2018 Sep 18.

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function.

Autor: Floyd BJ; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Wilkerson EM; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Veling MT; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Minogue CE; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Xia C; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA., Beebe ET; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Wrobel RL; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Cho H; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Kremer LS; Institute of Human Genetics, Technische Universität München, 81675 München, Germany; Institute of Human Genetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany., Alston CL; Wellcome Trust Centre for Mitochondrial Research, Institute of Neuroscience, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK., Gromek KA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Dolan BK; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Ulbrich A; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Stefely JA; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Bohl SL; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Werner KM; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA., Jochem A; Morgridge Institute for Research, Madison, WI 53715, USA., Westphall MS; Genome Center of Wisconsin, University of Wisconsin-Madison, Madison, WI 53706, USA., Rensvold JW; Morgridge Institute for Research, Madison, WI 53715, USA., Taylor RW; Wellcome Trust Centre for Mitochondrial Research, Institute of Neuroscience, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK., Prokisch H; Institute of Human Genetics, Technische Universität München, 81675 München, Germany; Institute of Human Genetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany., Kim JP; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA., Coon JJ; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA; Genome Center of Wisconsin, University of Wisconsin-Madison, Madison, WI 53706, USA., Pagliarini DJ; Morgridge Institute for Research, Madison, WI 53715, USA; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address: dpagliarini@morgridge.org.

Publikováno v: Molecular cell [Mol Cell] 2016 Aug 18; Vol. 63 (4), pp. 621-632. Date of Electronic Publication: 2016 Aug 04.

Automated gas-phase purification for accurate, multiplexed quantification on a stand-alone ion-trap mass spectrometer.

Autor: Vincent CE; Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States., Rensvold JW, Westphall MS, Pagliarini DJ, Coon JJ

Publikováno v: Analytical chemistry [Anal Chem] 2013 Feb 19; Vol. 85 (4), pp. 2079-86. Date of Electronic Publication: 2012 Oct 24.

Inhibitors of bacterial tubulin target bacterial membranes in vivo.

Autor: Foss MH; Departments of Biochemistry and Biomedical Engineering, 433 Babcock Drive, Madison, WI 53706, USA. Tel: +1 (608) 890-1342., Eun YJ, Grove CI, Pauw DA, Sorto NA, Rensvold JW, Pagliarini DJ, Shaw JT, Weibel DB

Publikováno v: MedChemComm [Medchemcomm] 2013 Jan 01; Vol. 4 (1), pp. 112-119. Date of Electronic Publication: 2012 Jul 18.