Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rensu Theart"'
Autor:
Erin Buchanan, Caitlyn Mahony, Sophia Bam, Mohamed Jaffer, Sarah Macleod, Asandile Mangali, Mignon van der Watt, Sholto de Wet, Rensu Theart, Caron Jacobs, Ben Loos, Colleen O’Ryan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Propionic acid (PPA) is used to study the role of mitochondrial dysfunction in neurodevelopmental conditions like autism spectrum disorders. PPA is known to disrupt mitochondrial biogenesis, metabolism, and turnover. However, the effect of P
Externí odkaz:
https://doaj.org/article/ea405245f5cb4ff49942b613f24a7e03
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Neurodegenerative diseases are often characterized by hydrophobic inclusion bodies, and it may be the case that the aggregate-prone proteins that comprise these inclusion bodies are in fact the cause of neurotoxicity. Indeed, the appearance of protei
Externí odkaz:
https://doaj.org/article/31435a9593784a0f876dd09b3d7703b9
The Highs and Lows of Memantine—An Autophagy and Mitophagy Inducing Agent That Protects Mitochondria
Autor:
Sholto de Wet, Asandile Mangali, Richard Batt, Jurgen Kriel, Nicola Vahrmeijer, Dana Niehaus, Rensu Theart, Ben Loos
Publikováno v:
Cells, Vol 12, Iss 13, p 1726 (2023)
Memantine is an FDA-approved, non-competitive NMDA-receptor antagonist that has been shown to have mitochondrial protective effects, improve cell viability and enhance clearance of Aβ42 peptide. Currently, there are uncertainties regarding the preci
Externí odkaz:
https://doaj.org/article/864be34d55e64b88950057bf1cd68c7a
The Highs and Lows of Memantine—An Autophagy and Mitophagy Inducing Agent That Protects Mitochondria
Autor:
Loos, Sholto de Wet, Asandile Mangali, Richard Batt, Jurgen Kriel, Nicola Vahrmeijer, Dana Niehaus, Rensu Theart, Ben
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1726
Memantine is an FDA-approved, non-competitive NMDA-receptor antagonist that has been shown to have mitochondrial protective effects, improve cell viability and enhance clearance of Aβ42 peptide. Currently, there are uncertainties regarding the preci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::9284e446ad5fd96f0c3498069d82e4c8
