Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Renqiu Hu"'
Publikováno v:
The Journal of Immunology. 167:1482-1489
Human IFN-α is a family of structurally related proteins that exhibit a wide range of antiproliferative activities. To understand the structural basis for these different antiproliferative activities, eight recombinant human IFN-α hybrids (HY) of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db7bcf6a51409977181fda07608ce9c
https://doi.org/10.4049/jimmunol.167.3.1482
https://doi.org/10.4049/jimmunol.167.3.1482
Autor:
Fan Dong, Renqiu Hu, Subhransu Ray, Philip M. Grimley, Karen H. Fields, Judy Beeler, Susette Audet, Hallgeir Rui, Hui Fang, Kathryn C. Zoon, Emanuel F. Petricoin
Publikováno v:
Blood. 91:3017-3027
Multiple biologic effects of interferon-α (IFN-α), including cell growth inhibition and antiviral protection, are initiated by tyrosine phosphorylation of STAT proteins. Although this signal pathway has been intensively investigated, the relevance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b019c5ae37fffc8c7227616b96b20dbb
https://doi.org/10.1182/blood.v91.8.3017.3017_3017_3027
https://doi.org/10.1182/blood.v91.8.3017.3017_3017_3027
Publikováno v:
Journal of Biological Chemistry. 268:12591-12595
The antiproliferative and competitive binding activities of 20 purified components of human lymphoblastoid interferon (IFN)-alpha were compared with that of recombinant human IFN-alpha 2b on Daudi and AU937 cells. We observed broad ranges of antiprol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793514940fee5e2100902a7b5b22fa77
https://doi.org/10.1016/s0021-9258(18)31429-7
https://doi.org/10.1016/s0021-9258(18)31429-7
Publikováno v:
Methods in molecular medicine. 116
Interferon (IFN)-alphas constitute a family of proteins exhibiting high degree of homology in primary, secondary, and tertiary structure and display a high level of species specificity in their biological properties. However, small structural differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5e90591edb42d36410ab72d89fd7018
https://pubmed.ncbi.nlm.nih.gov/16000855
https://pubmed.ncbi.nlm.nih.gov/16000855
Publikováno v:
Interferon Methods and Protocols ISBN: 9781588294180
Interferon (IFN)-alphas constitute a family of proteins exhibiting high degree of homology in primary, secondary, and tertiary structure and display a high level of species specificity in their biological properties. However, small structural differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f09495150d1648502a95b0f4d9966d92
https://doi.org/10.1385/1-59259-939-7:069
https://doi.org/10.1385/1-59259-939-7:069
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 22(4)
We compared the antigenic properties of human interferon-alpha2c (IFN-alpha2c), IFN-alpha21a, hybrids IFN-alpha21a/alpha2c, and their mutants, using a panel of 27 anti-IFN-alpha1, anti-IFN-alpha2, and anti-IFN-alpha8/1/8 monoclonal antibodies (mAb).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9edafebe61b4d9bfcccd828b6341f3b1
https://pubmed.ncbi.nlm.nih.gov/12034029
https://pubmed.ncbi.nlm.nih.gov/12034029
Publikováno v:
Proceedings of the National Academy of Sciences. 83:8226-8230
Treatment of Madin-Darby bovine kidney (MDBK) cells with human interferon (IFN)-alpha 2 at 37 degrees C results in a dose-dependent inhibition of cell growth and a reduction of the subsequent binding of 125I-labeled epidermal growth factor (EGF) at 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091daf39da20751b34eb4ea8130b6946
https://doi.org/10.1073/pnas.83.21.8226
https://doi.org/10.1073/pnas.83.21.8226