Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Renpeng Guo"'
Autor:
Nannan Zhao, Guoxing Yin, Chun Liu, Weiyu Zhang, Yang Shen, Dan Wang, Zhenzhen Lin, Jiao Yang, Jian Mao, Renpeng Guo, Yongwang Zhang, Feng Wang, Zhe Liu, Xinyi Lu, Lin Liu
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-25 (2023)
Abstract Telomeres, at the ends of chromosomes, protect chromosomes from fusion and preserve genomic stability. However, the molecular mechanisms underlying telomere attrition-induced genome instability remain to be understood. We systematically anal
Externí odkaz:
https://doaj.org/article/0e24d7dd97b1432f897393b110a79f48
Publikováno v:
Cells, Vol 11, Iss 3, p 456 (2022)
Proper telomere length is essential for indefinite self-renewal of embryonic stem (ES) cells and cancer cells. Telomerase-deficient late generation mouse ES cells and human ALT cancer cells are able to propagate for numerous passages, suggesting telo
Externí odkaz:
https://doaj.org/article/a8a782cc76594e9ea8fe3fe9fc504c21
Autor:
Renpeng Guo, Xiaoying Ye, Jiao Yang, Zhongcheng Zhou, Chenglei Tian, Hua Wang, Haiying Wang, Haifeng Fu, Chun Liu, Ming Zeng, Jun Yang, Lin Liu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Feeder cells are widely used for the culture of embryonic stem cells (ESCs), but their specific effects are not well known. Here, the authors demonstrate that mouse ESCs exhibit telomere loss and chromosomal aberrations associated with reduced Zscan4
Externí odkaz:
https://doaj.org/article/5ecd60b02aa5444a997fd7adbfe402ec
Autor:
Zheng Liu, Ling Lin, Haozhe Zhu, Zhongyuan Wu, Xi Ding, Rongrong Hu, Yichen Jiang, Changbo Tang, Shijie Ding, Renpeng Guo
Publikováno v:
Cells, Vol 10, Iss 11, p 3069 (2021)
Muscle stem cells (MuSCs) isolated ex vivo are essential original cells to produce cultured meat. Currently, one of the main obstacles for cultured meat production derives from the limited capacity of large-scale amplification of MuSCs, especially un
Externí odkaz:
https://doaj.org/article/3655f305a3c24ceb8f386ba6c94d5e77
Autor:
Xiaoxi Zhang, Jiao Yang, Haiying Wang, Renpeng Guo, Yu Yin, Dongdong Zhang, Qian Zhang, Hua Wang, Zhongcheng Zhou, Lingyi Chen, Jun Zhou, Lin Liu
Publikováno v:
Protein & Cell, Vol 8, Iss 5, Pp 360-364 (2017)
Externí odkaz:
https://doaj.org/article/5362d5d3a693401b876a4e93071e7ad1
Autor:
Na Liu, Yu Yin, Haiying Wang, Zhongcheng Zhou, Xiaoyan Sheng, Haifeng Fu, Renpeng Guo, Hua Wang, Jiao Yang, Peng Gong, Wen Ning, Zhenyu Ju, Yifei Liu, Lin Liu
Publikováno v:
PLoS Genetics, Vol 15, Iss 9, p e1008368 (2019)
Telomere shortening is associated with aging and age-associated diseases. Additionally, telomere dysfunction resulting from telomerase gene mutation can lead to premature aging, such as apparent skin atrophy and hair loss. However, the molecular sign
Externí odkaz:
https://doaj.org/article/637e7046eae84b3f8980ac7efebfc12b
Autor:
Jiao Yang, Renpeng Guo, Hua Wang, Xiaoying Ye, Zhongcheng Zhou, Jiameng Dan, Haiying Wang, Peng Gong, Wei Deng, Yu Yin, ShiQing Mao, Lingbo Wang, Junjun Ding, Jinsong Li, David L. Keefe, Meelad M. Dawlaty, Jianlong Wang, GuoLiang Xu, Lin Liu
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1809-1821 (2016)
Ten-eleven translocation (Tet) family proteins convert 5-methylcytosine to 5-hydroxymethylcytosine. We show that mouse embryonic stem cells (ESCs) depleted of Tet1 and/or Tet2 by RNAi exhibit short telomeres and chromosomal instability, concomitant w
Externí odkaz:
https://doaj.org/article/583a8ae977d24f889c5b25d7fbbde2bb
Autor:
Li-Ying Sung, Wei-Fang Chang, Qian Zhang, Chia-Chia Liu, Jun-Yang Liou, Chia-Chun Chang, Huan Ou-Yang, Renpeng Guo, Haifeng Fu, Winston T.K. Cheng, Shih-Torng Ding, Chuan-Mu Chen, Maja Okuka, David L. Keefe, Y. Eugene Chen, Lin Liu, Jie Xu
Publikováno v:
Cell Reports, Vol 9, Iss 5, Pp 1603-1609 (2014)
Summary: Haplo-insufficiency of telomerase genes in humans leads to telomere syndromes such as dyskeratosis congenital and idiopathic pulmonary fibrosis. Generation of pluripotent stem cells from telomerase haplo-insufficient donor cells would provid
Externí odkaz:
https://doaj.org/article/0dda26e42d754df58a0d8c0dadffabd6
Publikováno v:
Stem Cell Reviews and Reports.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::913dbfc3b6fbdba4c5e271534635b319
https://doi.org/10.1007/s12015-023-10535-z
https://doi.org/10.1007/s12015-023-10535-z
Autor:
Yumei Jia, Zhaoyuan Guo, Jiahao Zhu, Guanyu Qin, Wenwen Sun, Yu Yin, Haiying Wang, Renpeng Guo
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 750
Pluripotent embryonic stem cells (ESCs) can self-renew indefinitely and are able to differentiate into all three embryonic germ layers. Synaptosomal-associated protein 29 (Snap29) is implicated in numerous intracellular membrane trafficking pathways,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1172930d13543d0be35925f60a2ee02f