Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Renoud J. Marijnissen"'
Autor:
Jim Middelburg, Marjolein Sluijter, Gaby Schaap, Büşra Göynük, Katy Lloyd, Vitalijs Ovcinnikovs, Gijs G. Zom, Renoud J. Marijnissen, Christianne Groeneveldt, Lisa Griffioen, Gerwin G. W. Sandker, Sandra Heskamp, Sjoerd H. van der Burg, Tsolere Arakelian, Ferry Ossendorp, Ramon Arens, Janine Schuurman, Kristel Kemper, Thorbald van Hall
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract CD3 bispecific antibody (CD3 bsAb) therapy is clinically approved for refractory hematological malignancies, but responses in solid tumors have been limited so far. One of the main hurdles in solid tumors is the lack of sufficient T-cell inf
Externí odkaz:
https://doaj.org/article/36795cab2cda485e96053669065dc63a
Autor:
Joyce Aarts, Arjan van Caam, Xinlai Chen, Renoud J. Marijnissen, Monique M. Helsen, Birgitte Walgreen, Elly L. Vitters, Fons A. van de Loo, Peter L. van Lent, Peter M. van der Kraan, Marije I. Koenders
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract TGF-β1 is an important growth factor to promote the differentiation of T helper 17 (Th17) and regulatory T cells (Treg). The potential of TGF-β1 as therapeutic target in T cell-mediated diseases like rheumatoid arthritis (RA) is unclear. W
Externí odkaz:
https://doaj.org/article/e56341f6fbb745499f284ebee7d9f397
Autor:
L. Charlotte J. de Bree, Renoud J. Marijnissen, Junda M. Kel, Sietske K. Rosendahl Huber, Peter Aaby, Christine Stabell Benn, Marcel V. W. Wijnands, Dimitri A. Diavatopoulos, Reinout van Crevel, Leo A. B. Joosten, Mihai G. Netea, John Dulos
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/7f8678b8cd804c5489ae3fcebda8bf59
Autor:
L. Charlotte J. de Bree, Renoud J. Marijnissen, Junda M. Kel, Sietske K. Rosendahl Huber, Peter Aaby, Christine Stabell Benn, Marcel V. W. Wijnands, Dimitri A. Diavatopoulos, Reinout van Crevel, Leo A. B. Joosten, Mihai G. Netea, John Dulos
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Avian influenza A of the subtype H7N9 has been responsible for almost 1,600 confirmed human infections and more than 600 deaths since its first outbreak in 2013. Although sustained human-to-human transmission has not been reported yet, further adapta
Externí odkaz:
https://doaj.org/article/7a86a7e49a1b4fd5a94f8b6ec52de8d7
Autor:
Monique M. Helsen, Renoud J. Marijnissen, Wim B. van den Berg, Debbie M. Roeleveld, Birgitte Walgreen, Peter L E M van Lent, Peter M. van der Kraan, Marije I. Koenders, Liduine van den Bersselaar, Fons A. J. van de Loo
Publikováno v:
PLoS One, 12, 2
PLoS One, 12
PLoS ONE, Vol 12, Iss 2, p e0171757 (2017)
PLoS ONE
PLoS One, 12
PLoS ONE, Vol 12, Iss 2, p e0171757 (2017)
PLoS ONE
Contains fulltext : 173198.pdf (Publisher’s version ) (Open Access) Th17 cells and their cytokines are linked to the pathogenesis of rheumatoid arthritis, a chronic autoimmune disease characterized by joint inflammation. Th17 development is initiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ba9bd335fcbed5ce2472c6c070ec71
https://hdl.handle.net/2066/173198
https://hdl.handle.net/2066/173198
Autor:
Wim B. van den Berg, Cheryl Nickerson-Nutter, Fons A. J. van de Loo, Renoud J. Marijnissen, Deborah Young, Sabrina Garcia de Aquino, Annemieke M. H. Boots, Debbie M. Roeleveld, Shahla Abdollahi-Roodsaz, Annemiek B. van Spriel, Marije I. Koenders
Publikováno v:
Arthritis & Rheumatology. 66:886-895
OBJECTIVE: The cytokine interleukin-21 (IL-21) can have both proinflammatory and immunosuppressive effects. The purpose of this study was to investigate the potential dual role of IL-21 in experimental arthritis in relation to Th17 cells. METHODS: An
Autor:
Renoud J. Marijnissen, Marije I. Koenders, Annemieke M. H. Boots, Shahla Abdollahi-Roodsaz, John Dulos, Leo A. B. Joosten, Wim B. van den Berg, Fons A. J. van de Loo, Franco Di Padova
Publikováno v:
Arthritis and Rheumatism, 64, 6, pp. 1762-70
ARTHRITIS AND RHEUMATISM, 64(6), 1762-1770. John Wiley and Sons Inc.
Arthritis and Rheumatism, 64, 1762-70
ARTHRITIS AND RHEUMATISM, 64(6), 1762-1770. John Wiley and Sons Inc.
Arthritis and Rheumatism, 64, 1762-70
Item does not contain fulltext OBJECTIVE: To provide an intermediate step between classic arthritis models and clinical trials, the rheumatoid arthritis (RA) synovium SCID mouse model is a valuable tool for use during preclinical research. We underto
Autor:
Wim B. van den Berg, Mario M. Zaiss, Jochen Zwerina, Karin Zwerina, Renoud J. Marijnissen, Iain Mclnnes, Georg Schett, Leo A. B. Joosten, Axel J. Hueber, Marije I. Koenders, Gisela Ruiz Heiland, Wolfgang Baum
Publikováno v:
European Journal of Immunology. 42:413-423
Tumour necrosis factor alpha (TNF-α) is a major inducer for inflammation and bone loss. Here, we investigated whether interleukin (IL)-17 plays a role in TNF-α-mediated inflammation and bone resorption. Human TNF-α transgenic (hTNFtg) mice were tr
Autor:
Cheryl Nickerson-Nutter, Renoud J. Marijnissen, Mark H. T. Stappers, Marije I. Koenders, Annemieke M. H. Boots, Wim B. van den Berg, Leo A. B. Joosten, Ruben L. Smeets
Publikováno v:
Arthritis & Rheumatism. 63:2939-2948
OBJECTIVE: Interleukin-22 (IL-22) is a mediator in antimicrobial responses and inflammatory autoimmune diseases. Although IL-22 and its receptor, IL-22R, have been identified in the synovium of rheumatoid arthritis patients, the source of IL-22 and i
Autor:
Bernard Lauwerys, Franco Di Padova, Leo A. B. Joosten, Wim B. van den Berg, Marije I. Koenders, Mihai G. Netea, P. Durez, Kim Timmermans, Renoud J. Marijnissen, Jos W. M. van der Meer, Ilse Gutierrez-Roelens, Frank L. van de Veerdonk
Publikováno v:
Arthritis and Rheumatism, 63, 6, pp. 1507-16
Arthritis and Rheumatism, 63, 1507-16
Arthritis and Rheumatism, 63, 1507-16
Contains fulltext : 98411.pdf (Publisher’s version ) (Closed access) OBJECTIVE: Rituximab has been shown to be successful in the treatment of rheumatoid arthritis (RA), and this unexpected finding indicates that B cells have an important role in th