Výsledky vyhledávání - "Reno Pontarollo"

BoLA class I allele diversity and polymorphism in a herd of cattle

Autor: Reno Pontarollo, Chenhong Zhang, Shawn Babiuk, Mik Bickis, Benjamin Horseman, Anthony Kusalik, Mitchell S. Abrahamsen, Lawrence B. Schook

Publikováno v: Immunogenetics. 59:167-176

Major histocompatibility complex class I genes are among the most polymorphic genes characterized. The high level of polymorphism is essential for generating host immune responses. In humans, three distinct genomic loci encode human leukocyte antigen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66491eb08bbeb390198ee3be02713cc4
https://doi.org/10.1007/s00251-006-0173-7

Zobrazit plný text záznamu

TLR9-/- and TLR9+/+ mice display similar immune responses to a DNA vaccine

Autor: Reno Pontarollo, Rolf Hecker, Sylvia van Drunen Littel-van den Hurk, Neeloffer Mookherjee, Shawn Babiuk, Lorne A. Babiuk, P. Griebel

Publikováno v: Immunology. 113:114-120

Plasmid DNA continues to attract interest as a potential vaccine-delivery vehicle. However, the mechanisms whereby immune responses are elicited by plasmids are not fully understood. Although there have been suggestions regarding the importance of Cp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59c8ecca8833e0175c73d7bf546310a
https://doi.org/10.1111/j.1365-2567.2004.01938.x

Zobrazit plný text záznamu

Augmentation of cellular immune responses to bovine herpesvirus-1 glycoprotein D by vaccination with CpG-enhanced plasmid vectors

Autor: S. van Drunen Littel-van den Hurk, Rolf Hecker, Reno Pontarollo, Lorne A. Babiuk

Publikováno v: Journal of General Virology. 83:2973-2981

The potential of CpG-enhanced plasmid DNA vectors encoding a truncated secreted form of bovine herpesvirus-1 (BHV-1) glycoprotein D (tgD) to induce enhanced immune responses in cattle was investigated. We created tgD expression plasmids containing 0,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72c92a67412abaea3797c4c2510cd43
https://doi.org/10.1099/0022-1317-83-12-2973

Zobrazit plný text záznamu

CpG-containing oligodeoxynucleotides augment and switch the immune responses of cattle to bovine herpesvirus-1 glycoprotein D*1

Autor: Dale L. Godson, Susantha Gomis, B.C. Karvonen, Robert Rankin, Philip Willson, Lorne A. Babiuk, S. van Drunen Littel-van den Hurk, Reno Pontarollo, B. I. Loehr, Rolf Hecker

Publikováno v: Vaccine. 20:3014-3022

The adjuvanticity of a synthetic oligodeoxynucleotide containing unmethylated CpG motifs (CpG ODN) was determined in cattle. Calves were immunized with a truncated secreted version of glycoprotein D (tgD) of bovine herpes virus-1 (BHV-1) formulated w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14c564d45d702ba1d8e780c10b36c183
https://doi.org/10.1016/s0264-410x(02)00216-5

Zobrazit plný text záznamu

Priming by DNA immunization augments T-cell responses induced by modified live bovine herpesvirus vaccine

Autor: B. I. Loehr, Reno Pontarollo, Robert Rankin, Laura J.P. Latimer, S. van Drunen Littel-van den Hurk, Lorne A. Babiuk, P. Willson

Publikováno v: Journal of General Virology. 82:3035-3043

DNA vaccines have several advantages over conventional vaccines. One of the most important characteristics is the presentation of antigen via both MHC class I and class II receptors. Although this generally results in strong T-cell responses, antibod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c664d2296dc07bcd247720cb6589cfd
https://doi.org/10.1099/0022-1317-82-12-3035

Zobrazit plný text záznamu

Suppository-Mediated DNA Immunization Induces Mucosal Immunity against Bovine Herpesvirus-1 in Cattle

Autor: P. Willson, Lorne A. Babiuk, S. van Drunen Littel-van den Hurk, Robert Rankin, Reno Pontarollo, T. King, B. I. Loehr

Publikováno v: Virology. 289:327-333

Mucosal surfaces are the primary sites for the transmission of infectious agents including viruses, so effective vaccines generally should induce mucosal immunity. Furthermore, noninvasive delivery is desirable because of the ease of application, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188103ce44a3fbce0615625e2b1f74c4
https://doi.org/10.1006/viro.2001.1143

Zobrazit plný text záznamu

CpG Motif Identification for Veterinary and Laboratory Species Demonstrates That Sequence Recognition Is Highly Conserved

Autor: Lorne A. Babiuk, Sylvia van Drunen Littel-van den Hurk, Arthur M. Krieg, Robert Rankin, X. P. Ioannou, Reno Pontarollo, Rolf Hecker

Publikováno v: Antisense and Nucleic Acid Drug Development. 11:333-340

Oligodinucleotides containing CpG motifs stimulate vertebrate immune cells in vitro, have proven efficacy in murine disease models and are currently being tested in human clinical trials as therapies for cancer, allergy, and infectious disease. As th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd3f52e4fd0bca197a416e4ceb78304
https://doi.org/10.1089/108729001753231713

Zobrazit plný text záznamu

Effects of intradermally administered plasmid deoxyribonucleic acid on ovine popliteal lymph node morphology

Autor: Richard R. E. Uwiera, P. Adams, Greg, Robert Rankin, Philip J. Griebel, Dorothy M. Middleton, Lorne, A. Babiuk, Reno Pontarollo, Sylvia van Drunen Littel-van den Hurk

Publikováno v: The Anatomical Record. 262:186-192

In the last decade it has become apparent that bacterial deoxyribonucleic acid (DNA) is recognized as a “danger signal” by the mammalian immune system. To investigate this interaction, sheep were injected intradermally two centimeters distal to t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7762cd5e206b41e7fa5a4837c5b834c
https://doi.org/10.1002/1097-0185(20010201)262:2<186::aid-ar1024>3.0.co

Zobrazit plný text záznamu

Recent advances in the use of DNA vaccines for the treatment of diseases of farmed animals

Autor: Lorne A. Babiuk, Reno Pontarollo, Robert Rankin, Sylvia van Drunen Littel-van den Hurk, B. I. Loehr, Richard R. E. Uwiera, Volker Gerdts

Publikováno v: Advanced Drug Delivery Reviews. 43:13-28

DNA-based vaccination constitutes one of the most recent approaches to vaccine development. This technology is in principle one of the most simple and yet versatile methods of inducing both humoral and cellular immune responses, as well as protection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8565f7aa5330bfb5ec046a57549fe28
https://doi.org/10.1016/s0169-409x(00)00074-0

Zobrazit plný text záznamu

Cloning and characterization of bacteriophage-like DNA from Haemophilus somnus homologous to phages P2 and HP1

Autor: Reno Pontarollo, Clement Rioux, Andrew A. Potter

Publikováno v: Journal of Bacteriology. 179:1872-1879

In an attempt to identify and characterize components of a heme uptake system of Haemophilus somnus, an Escherichia coli cosmid library of H. somnus genomic DNA was screened for the ability to bind hemin (Hmb+). The Hmb+ phenotype was associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698bbc08cd95b5d49cf75c7daa0f087d
https://doi.org/10.1128/jb.179.6.1872-1879.1997

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání