Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice

Autor: Renna, Stephanie A., Michael, James V., Kong, Xianguo, Ma, Lin, Ma, Peisong, Nieman, Marvin T., Edelstein, Leonard C., McKenzie, Steven E. ^*

Publikováno v: In Journal of Thrombosis and Haemostasis May 2022 20(5):1236-1247

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Human PAR4 Is a More Potent Receptor for Activating Platelets Than Mouse PAR4

Autor: Renna, Stephanie ^*, Edelstein, Leonard C., McKenzie, Steven Edward

Publikováno v: In Blood 13 November 2019 134 Supplement 1:4883-4883

TULA-2 (T-Cell Ubiquitin Ligand-2) Inhibits the Platelet Fc Receptor for IgG IIA (FcγRIIA) Signaling Pathway and Heparin-Induced Thrombocytopenia in Mice.

Autor: Yuhang Zhou, Abraham, Shaji, Renna, Stephanie, Edelstein, Leonard C., Dangelmaier, Carol A., Tsygankov, Alexander Y., Kunapuli, Satya P., Bray, Paul F., McKenzie, Steven E.

Publikováno v: Arteriosclerosis, Thrombosis & Vascular Biology; Dec2016, Vol. 36 Issue 12, p2315-2323, 9p, 6 Graphs

A Mouse Model of the Protease Activated Receptor 4 (PAR4) Pro310Leu Variant has Reduced Platelet Reactivity.

Autor: Han X; Department of Pharmacology, Case Western Reserve University, Cleveland, OH United States., Knauss EA; Department of Pharmacology, Case Western Reserve University, Cleveland, OH United States., de la Fuente M; Department of Pharmacology, Case Western Reserve University, Cleveland, OH United States., Li W; Department of Biomedical Sciences, Joan C. Edwards School of Medicine at Marshall University, Huntington, WV United States., Conlon RA; Case Transgenic and Targeting Facility, Case Western Reserve University, Cleveland, OH United States., LePage DF; Case Transgenic and Targeting Facility, Case Western Reserve University, Cleveland, OH United States., Jiang W; Case Transgenic and Targeting Facility, Case Western Reserve University, Cleveland, OH United States., Renna SA; Department of Medicine, The Cardeza Foundation for Hematologic Research, Thomas Jefferson University, Philadelphia, PA United States., McKenzie SE; Department of Medicine, The Cardeza Foundation for Hematologic Research, Thomas Jefferson University, Philadelphia, PA United States., Nieman MT; Department of Pharmacology, Case Western Reserve University, Cleveland, OH United States.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 01. Date of Electronic Publication: 2023 Dec 01.