Hypoxia induced deregulation of sphingolipids in colon cancer is a prognostic marker for patient outcome.

Autor: El Hindi K; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany., Brachtendorf S; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany., Hartel JC; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany; Goethe-University Frankfurt, Department of Life Sciences, 60590 Frankfurt, Germany., Renné C; Institute of Pathology and Cytology, Group Practice Wiesbaden, Germany., Birod K; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany., Schilling K; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany., Labocha S; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany., Thomas D; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany., Ferreirós N; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany., Hahnefeld L; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany., Dorochow E; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany., Del Turco D; Goethe-University Frankfurt, Institute of Clinical Neuroanatomy, Dr. Senckenberg Anatomy, Faculty of Medicine, Theodor Stern Kai 7, 60596 Frankfurt am Main, Germany., Deller T; Goethe-University Frankfurt, Institute of Clinical Neuroanatomy, Dr. Senckenberg Anatomy, Faculty of Medicine, Theodor Stern Kai 7, 60596 Frankfurt am Main, Germany., Scholich K; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany., Fuhrmann DC; Goethe-University Frankfurt, Institute of Biochemistry I, Faculty of Medicine, Theodor-Stern-Kai 7, 60596 Frankfurt, Germany., Weigert A; Goethe-University Frankfurt, Institute of Biochemistry I, Faculty of Medicine, Theodor-Stern-Kai 7, 60596 Frankfurt, Germany., Brüne B; Goethe-University Frankfurt, Institute of Biochemistry I, Faculty of Medicine, Theodor-Stern-Kai 7, 60596 Frankfurt, Germany., Geisslinger G; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany., Wittig I; Goethe-University Frankfurt, Functional Proteomics, Institute of Cardiovascular Physiology, Faculty of Medicine, Frankfurt am Main, Germany., Link KH; Asklepios Tumor Center (ATC) and Surgical Center, Asklepios Paulinen Klinik, Wiesbaden 65197, Germany., Grösch S; Goethe-University Frankfurt, Institute of Clinical Pharmacology, Faculty of Medicine, Theodor Stern Kai 7, 60590 Frankfurt, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany. Electronic address: groesch@em.uni-frankfurt.de.

Publikováno v: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2024 Jan; Vol. 1870 (1), pp. 166906. Date of Electronic Publication: 2023 Oct 04.

Insights into the multistep transformation process of lymphomas: IgH-associated translocations and tumor suppressor gene mutations in clonally related composite Hodgkin's and non-Hodgkin's lymphomas.

Autor: Schmitz, R.¹ roland.schmitz@uni-essen.de, Renné, C.², Rosenquist, R.³, Tinguely, M.⁴, Distler, V.^1,2, Menestrina, F.⁵, Lestani, M.⁵, Stankovic, T.⁶, Austen, B.⁶, Bräuninger, A.², Hansmann, M.-L.², Küppers, R.¹

Publikováno v: Leukemia (08876924). Aug2005, Vol. 19 Issue 8, p1452-1458. 7p.

Molecular Biomarkers in Prediction of High-Grade Transformation and Outcome in Patients with Follicular Lymphoma: A Comprehensive Systemic Review.

Autor: Enemark, Marie Hairing^1,2 (AUTHOR) mariem@rm.dk, Hemmingsen, Jonas Klejs¹ (AUTHOR) johemm@rm.dk, Jensen, Maja Lund¹ (AUTHOR) majalj@rm.dk, Kridel, Robert³ (AUTHOR) robert.kridel@uhn.ca, Ludvigsen, Maja^1,2 (AUTHOR) majlud@rm.dk

Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 20, p11179. 52p.

The Major Myosin-binding Site of Caldesmon Resides Near Its N-terminal Extreme

Autor: Hongqiu Guo, Shaobin Zhuang, Yanhua Li, Renné C. Lu, C.-L. Albert Wang, Katsuhide Mabuchi

Publikováno v: Journal of Biological Chemistry. 275:10989-10994

The primary myosin-binding site of caldesmon was thought to be in the N-terminal region of the molecule, but the exact nature of the caldesmon-myosin interaction has not been well characterized. A caldesmon fragment that encompasses residues 1-240 (N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffdae719a57a7f492dd79208e8b3ab5
https://doi.org/10.1074/jbc.275.15.10989

Pharmacogenetic Approach to Tramadol Use in the Arab Population.

Autor: Kwon, Chan-Hyuk¹ (AUTHOR), Ha, Min Woo^2,3 (AUTHOR) minuha@jejunu.ac.kr

Publikováno v: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p8939. 10p.