Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Renming Fan"'
Autor:
Renming Fan, Ruizhuo Lin, Shuo Zhang, Aohua Deng, Yongrui Hai, Junyan Zhuang, Yang Liu, Maosheng Cheng, Gaofei Wei
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1742-1758 (2024)
Mitochondrial membrane remodeling can trigger the release of mitochondrial DNA (mtDNA), leading to the activation of cellular oxidative stress and immune responses. While the role of mitochondrial membrane remodeling in promoting inflammation in hepa
Externí odkaz:
https://doaj.org/article/2246674c496b4cbdaf7c70db58d65f07
Autor:
Renming Fan, Aohua Deng, Ruizhuo Lin, Shuo Zhang, Caiyan Cheng, Junyan Zhuang, Yongrui Hai, Minggao Zhao, Le Yang, Gaofei Wei
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Ferroptosis is an iron‐dependent cell death form that initiates lipid peroxidation (LPO) in tumors. In recent years, there has been growing interest on ferroptosis, but how to propel it forward translational medicine remains in mist. Altho
Externí odkaz:
https://doaj.org/article/1f72fe9e26cf4b11a50c98ddb6416e36
Autor:
Yongrui Hai, Renming Fan, Ting Zhao, Ruizhuo Lin, Junyan Zhuang, Aohua Deng, Shanshui Meng, Zhuang Hou, Gaofei Wei
Publikováno v:
Pharmacological Research, Vol 202, Iss , Pp 107115- (2024)
Dihydroorotate dehydrogenase (DHODH)-mediated ferroptosis defense is a targetable vulnerability in cancer. Currently, only a few DHODH inhibitors have been utilized in clinical practice. To further enhance DHODH targeting, we introduced the mitochond
Externí odkaz:
https://doaj.org/article/0f0a8868cb46407fb20e10e039054461
Autor:
Renming Fan, Aohua Deng, Bing Qi, Shuo Zhang, Ruoxi Sang, Lanxin Luo, Jiakui Gou, Yongqing Liu, Ruizhuo Lin, Minggao Zhao, Yang Liu, Le Yang, Maosheng Cheng, Gaofei Wei
Publikováno v:
Journal of Medicinal Chemistry. 66:875-889
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ebb6597f7304249d8698ca0c8175ab
https://doi.org/10.1021/acs.jmedchem.2c01719
https://doi.org/10.1021/acs.jmedchem.2c01719