Zobrazeno 1 - 10
of 592
pro vyhledávání: '"Renjie, Chai"'
Autor:
Xiangyu Ma, Li-Nan Chen, Menghui Liao, Liyan Zhang, Kun Xi, Jiamin Guo, Cangsong Shen, Dan-Dan Shen, Pengjun Cai, Qingya Shen, Jieyu Qi, Huibing Zhang, Shao-Kun Zang, Ying-Jun Dong, Luwei Miao, Jiao Qin, Su-Yu Ji, Yue Li, Jianfeng Liu, Chunyou Mao, Yan Zhang, Renjie Chai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The class C orphan G-protein-coupled receptor (GPCR) GPR156, which lacks the large extracellular region, plays a pivotal role in auditory function through Gi2/3. Here, we firstly demonstrate that GPR156 with high constitutive activity is ess
Externí odkaz:
https://doaj.org/article/eda175ba92a2443a9b31648e453755f1
Autor:
Yangnan Hu, Hao Wei, Menghui Liao, Shanying Han, Xin Gao, Yusong Wang, Shan Zhou, Dongyu Xu, Xugang Zhuang, Ye Yang, Hong Cheng, Bin Zhang, Qingyue Cui, Jieyu Qi, Lei Tian, Wenyan Li, Xia Gao, Renjie Chai
Publikováno v:
Engineered Regeneration, Vol 5, Iss 4, Pp 443-451 (2024)
Cochlear implantation (CI) offers a dependable treatment for sensorineural hearing loss, with precision electroacoustic stimulation parameters showing great potential in improving auditory outcomes in CI patients. Here, we report the attachment of MX
Externí odkaz:
https://doaj.org/article/69b2add64537406f883c01a438f81cd3
Autor:
Bin Chen, Cheng Cheng, Yunhao Wu, Siyu Li, Mo Han, Le Zhen, Ying Peng, Suhan Guo, Kaidi Shen, Xia Gao, Renjie Chai, Guangji Wang, Fang Zhou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4413-4430 (2024)
Ototoxicity and nephrotoxicity are the most prevalent side effects of aminoglycoside antibiotics (gentamicin, amikacin, neomycin) and platinum anti-tumor drugs (cisplatin, carboplatin). The inner ear and kidney share similarities in drug deposition a
Externí odkaz:
https://doaj.org/article/b706e7dca6f446dbb61c9606fa7738b9
Autor:
Bin Zhang, Yangnan Hu, Haoliang Du, Shanying Han, Lei Ren, Hong Cheng, Yusong Wang, Xin Gao, Shasha Zheng, Qingyue Cui, Lei Tian, Tingting Liu, Jiaqiang Sun, Renjie Chai
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Cochlear implants can directly activate the auditory system’s primary sensory neurons, the spiral ganglion neurons (SGNs), via circumvention of defective cochlear hair cells. This bypass restores auditory input to the brainstem. SGN loss e
Externí odkaz:
https://doaj.org/article/826a3c81f2d74d30b2e88e9559d01850
Autor:
Qiuhan Sun, Fangzhi Tan, Xinlin Wang, Xingliang Gu, Xin Chen, Yicheng Lu, Nianci Li, Xiaoyun Qian, Yinyi Zhou, Ziyu Zhang, Man Wang, Liyan Zhang, Busheng Tong, Jieyu Qi, Renjie Chai
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102396- (2024)
Inner ear hair cell (HC) damage is irreversible in mammals, but it has been shown that supporting cells (SCs) have the potential to differentiate into HCs. Serpine2, a serine protease inhibitor, encodes protease nexin 1, and this has been suggested t
Externí odkaz:
https://doaj.org/article/b08deec598944730915cc540aac955cd
Autor:
Xue Wang, Lei Xu, Yu Meng, Fang Chen, Jinzhu Zhuang, Man Wang, Weibin An, Yuechen Han, Bo Chu, Renjie Chai, Wenwen Liu, Haibo Wang
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract Mammalian cochlea spiral ganglion neurons (SGNs) are crucial for sound transmission, they can be damaged by chemotherapy drug cisplatin and lead to irreversible sensorineural hearing loss (SNHL), while such damage can also render cochlear im
Externí odkaz:
https://doaj.org/article/7e89f283698844cdb04654baf05646d0
Autor:
Wenhui Zhang, Yangnan Hu, Pan Feng, Zhe Li, Hui Zhang, Bin Zhang, Dongyu Xu, Jieyu Qi, Huan Wang, Lei Xu, Zhou Li, Ming Xia, Jilai Li, Renjie Chai, Lei Tian
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Photonic crystals are a new class of optical microstructure materials characterized by a dielectric constant that varies periodically with space and features a photonic bandgap. Inspired by natural photonic crystals such as butterfly scales,
Externí odkaz:
https://doaj.org/article/1ae5231b319a4f018ad6af6b3f4cd7ba
Autor:
Yiyun Lou, Jiaoyao Ma, Yangnan Hu, Xiaoying Yao, Yaoqian Liu, Mingxuan Wu, Gaogan Jia, Yan Chen, Renjie Chai, Mingyu Xia, Wenyan Li
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract The physiological interactions between the peripheral and central auditory systems are crucial for auditory information transmission and perception, while reliable models for auditory neural circuits are currently lacking. To address this is
Externí odkaz:
https://doaj.org/article/14b5eceb7bc94fb2bc9fbe5259a7e7c4
Autor:
Hui Zhang, Dongyu Xu, Bin Zhang, Xiaofan Li, Minli Li, Chen Zhang, Huan Wang, Yuanjin Zhao, Renjie Chai
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Advanced artificial nerve conduits offer a promising alternative for nerve injury repair. Current research focuses on improving the therapeutic effectiveness of nerve conduits by optimizing scaffold materials and functional components. In th
Externí odkaz:
https://doaj.org/article/931be328d2c5405ab3e5b472716d6eff
Autor:
Liyan Zhang, Xin Chen, Xinlin Wang, Yinyi Zhou, Yuan Fang, Xingliang Gu, Ziyu Zhang, Qiuhan Sun, Nianci Li, Lei Xu, Fangzhi Tan, Renjie Chai, Jieyu Qi
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Mammalian cochlear hair cells (HCs) are essential for hearing, and damage to HCs results in severe hearing impairment. Damaged HCs can be regenerated by neighboring supporting cells (SCs), thus the functional regeneration of HCs is the main
Externí odkaz:
https://doaj.org/article/32b86c7e433442648dea89a281db3ab4