Výsledky vyhledávání - "Renieramycin G"

Synthesis and cytotoxicity of (-)-homo-renieramycin G and its derivatives

Autor: Baohe Guan, Xuan Pan, Zhanzhu Liu, Yantao Ma, Guangyan Zhang

Publikováno v: Organicbiomolecular chemistry. 18(48)

(-)-Homo-renieramycin G and its twenty derivatives were prepared from l-tyrosine methyl ester via a multi-step route. Their cytotoxicities were tested against four human cancer cell lines (A549, HeLa, KB and BGC-823). (-)-Renieramycin G and (-)-homo-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9dd81c26c4b9dcd064c947fc144eb1
https://pubmed.ncbi.nlm.nih.gov/33300542

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Asymmetric total synthesis of three stereoisomers of (−)-renieramycin G and their cytotoxic activities

Autor: Nan Wang, Enming Du, Wenfang Dong, Xuan Pan, Zhanzhu Liu, Baohe Guan, Zheng Yan, Li Li

Publikováno v: Tetrahedron. 71:4296-4303

(−)-Renieramycin G, a marine antitumor natural product, is a typical member of the bis-tetrahydroisoquinoline alkaloid family. In this paper, an efficient protocol of asymmetric total synthesis of its three stereoisomers, (+)-renieramycin G, 11,13-

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https://doi.org/10.1016/j.tet.2015.04.064

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Chemistry of renieramycins. Part 12: An improved total synthesis of (±)-renieramycin G

Autor: Hiroki Takada, Masahiro Mimura, Kimiko Shinada-Fujino, Saiko Yoshida, Masashi Yokoya, Naoki Saito

Publikováno v: Tetrahedron. 68:4166-4181

An improved total synthesis of (±)-renieramycin G (1g) from readily available 2-hydroxy-3-methyl-4,5-dimethoxybenzaldehyde (7) in 21 steps (6.3% overall yield) is described. The synthesis features the concise construction of a pentacyclic framework

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d0f9e5a16294847dd25681b1174a017
https://doi.org/10.1016/j.tet.2012.03.105

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Chemistry of renieramycins. Part 9: Stereocontrolled total synthesis of (±)-renieramycin G

Autor: Masashi Yokoya, Kimiko Shinada-Fujino, Naoki Saito

Publikováno v: Tetrahedron Letters. 52:2446-2449

A 25-step stereocontrolled total synthesis of (±)-renieramycin G (1g) from readily available 2-hydroxy-3-methyl-4,5-dimethoxybenzaldehyde (3) is described. This synthesis features the concise construction of the pentacyclic framework using the stere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80ecb0f592efc5c61c2755820cb267d6
https://doi.org/10.1016/j.tetlet.2011.02.055

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Asymmetric Total Syntheses of (−)-Renieramycin M and G and (−)-Jorumycin Using Aziridine as a Lynchpin

Autor: Jieping Zhu, Yan-Chao Wu

Publikováno v: Organic Letters
Organic Letters, American Chemical Society, 2009, 11 (23), pp.5558-61. ⟨10.1021/ol9024919⟩

Using ring opening and Pictet-Spengler reactions of nonracemic amino acid-derived aziridine building blocks as key steps, (-)-renieramycin M I [R = (Z)-MeCH:CMeCO; R = NC; R1 = H], (-)-renieramycin G I [R = (Z)-MeCH:CMeCO; RR1 = O], (-)-jorumycin I (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564185619673504d2bde14840bf1b4be
https://doi.org/10.1021/ol9024919

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ChemInform Abstract: A Rapid and Efficient Access to Renieramycin-Type Alkaloids Featuring a Temperature-Dependent Stereoselective Cyclization

Autor: Hao Liu, Ruijiao Chen, Xiaochuan Chen

Publikováno v: ChemInform. 45

A flexible protocol for the asymmetric synthesis of renieramycin-type alkaloids, such as Renieramycin G (III) and Jorunnamycin A (IV), in which the spontaneous lactamization of (I) after N-deprotection is employed to construct the pentacyclic framewo

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https://doi.org/10.1002/chin.201427212

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Renieramycin g, a new alkaloid from the sponge xestospongia caycedoi

Autor: Bradley S. Davidson

Publikováno v: Tetrahedron Letters. 33:3721-3724

A new cytotoxic alkaloid, renieramycin G ( 8 ), was isolated, along with previously reported metabolites mimosamycin ( 1 ), renierol ( 2 ), and N -formyl-1,2-dihydrorenierone ( 3 ), from the Fijian sponge Xestospongia caycedoi . The structure of reni

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https://doi.org/10.1016/s0040-4039(00)91997-x

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