Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Renhuan Xu"'
Autor:
Jane Qin, Ju Hyeong Jeon, Jiangsheng Xu, Laura Katherine Langston, Ramesh Marasini, Stephanie Mou, Brian Montoya, Carolina R. Melo-Silva, Hyo Jin Jeon, Tianyi Zhu, Luis J. Sigal, Renhuan Xu, Huabin Zhu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Because of the rapid mutations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an effective vaccine against SARS-CoV-2 variants is needed to prevent coronavirus disease 2019 (COVID-19). T cells, in addition to neutralizing antibodies
Externí odkaz:
https://doaj.org/article/ddc2c09a6186455b81257302ddc3eeb6
Autor:
Tao Wang, Herbert Kim Lyerly, Alan Chen Chen, Renhuan Xu, Junping Wei, Xiao-Yi Yang, Cong-Xiao Liu, Gangjun Lei, Teri Heiland, Zachary Conrad Hartman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background The advent of immune checkpoint blockade antibodies has demonstrated that effective mobilization of T cell responses can cause tumor regression of metastatic cancers, although these responses are heterogeneous and restricted to certain his
Externí odkaz:
https://doaj.org/article/6cdeb5056cb243e1839fdc148a8a38ff
Publikováno v:
Cancer Research. 82:3553-3553
CD40 ligand (CD40L; CD154) is a transmembrane protein expressed on the surface of activated T cells, particularly on CD4 T cells, that stimulates CD40-dependent activation of antigen-presenting cells, resulting in enhancement of T cell and antibody r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e0e4526d240d2a933bb3ae7a2cfe5ee
https://doi.org/10.1158/1538-7445.am2022-3553
https://doi.org/10.1158/1538-7445.am2022-3553
Autor:
Robert D. Marek, Alan Chen, Renhuan Xu, Junping Wei, Tao Wang, Xiao Yang, Gangjun Lei, Teri Heiland, Zachary C. Hartman
Publikováno v:
Cancer Research. 82:3564-3564
Background: Immune checkpoint blockade (ICB) antibodies have demonstrated that effective induction of T cell responses can elicit tumor regression of different metastatic cancers, although these responses are restricted to certain individuals with sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f71dd7d08f75b21aae2df7a186191d0a
https://doi.org/10.1158/1538-7445.am2022-3564
https://doi.org/10.1158/1538-7445.am2022-3564
Autor:
Renhuan Xu, Teri Heiland, Alan Chen Chen, Zachary C. Hartman, Xiao Yi Yang, Gangjun Lei, Herbert Kim Lyerly, Junping Wei, Tao Wang, Cong-Xiao Liu
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
BackgroundThe advent of immune checkpoint blockade antibodies has demonstrated that effective mobilization of T cell responses can cause tumor regression of metastatic cancers, although these responses are heterogeneous and restricted to certain hist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d94443d006a1a7d4ea3041fb5997f4fb
https://pubmed.ncbi.nlm.nih.gov/32532838
https://pubmed.ncbi.nlm.nih.gov/32532838
Autor:
Renhuan Xu, Teri Heiland
Publikováno v:
Cancer Research. 79:LB-204
DNA vaccines have emerged as an attractive immunotherapeutic approach against infectious diseases and cancer due to its fast, efficient design and validation. It remains, however, a challenge in clinical settings due to historically low levels of imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e0f276be367366af648ca58a68fba79
https://doi.org/10.1158/1538-7445.am2019-lb-204
https://doi.org/10.1158/1538-7445.am2019-lb-204
Autor:
Renhuan Xu, Luis Sigal
Publikováno v:
The Journal of Immunology. 186:106.27-106.27
Type 1 interferons (T1-IFNs) play a major role in antiviral defense. Orthopoxviruses, including those that produce smallpox and mousepox encode a decoy receptor for T1-IFN, the T1-IFN binding protein (T1-IFNbp), which is essential for virulence. We d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6673879ceadecac74b7c985332b1e1d9
https://doi.org/10.4049/jimmunol.186.supp.106.27
https://doi.org/10.4049/jimmunol.186.supp.106.27
Autor:
Renhuan Xu, Luis Sigal
Publikováno v:
The Journal of Immunology. 184:39.21-39.21
It is currently though that the neutralizing antibodies (Abs) are the most effective way to prevent viral infection. However, our recent work has shown that mousepox (the mouse equivalent of human smallpox) can be prevented by immunization with the T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8174f50d170e4d9bd923c346fbcfdd3
https://doi.org/10.4049/jimmunol.184.supp.39.21
https://doi.org/10.4049/jimmunol.184.supp.39.21
Autor:
Renhuan Xu, Luis Sigal
Publikováno v:
The Journal of Immunology. 182:128.30-128.30
Ectromelia virus (ECTV) is an Orthopoxvirus (OPV) that causes mousepox, the murine equivalent of human smallpox caused by the OPV Variola virus (VARV). Both ECTV and VARV encode a Type I IFN binding protein (EVM166 in ECTV) that inactivates IFNĄ.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a550d402110bcf5aebe447579171261
https://doi.org/10.4049/jimmunol.182.supp.128.30
https://doi.org/10.4049/jimmunol.182.supp.128.30