Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Renhua, Fan"'
Publikováno v:
Green Synthesis and Catalysis, Vol 3, Iss 3, Pp 282-286 (2022)
Chiral N-alkylated indoles are privileged structural motifs found in many natural products and pharmaceuticals and a search for effective methods with which to prepare chiral N-alkylated indoles is ongoing. Efficient syntheses of enantioenriched N-al
Externí odkaz:
https://doaj.org/article/9b87e44429454f99a7a2f4bbc944ce30
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Atom insertion into aromatic carbon-nitrogen (C-N) bonds is useful for the synthesis of nitrogen-containing molecules, but challenging due to the inert nature of these bonds. Here, the authors report one-carbon insertion into aromatic C-N bonds to di
Externí odkaz:
https://doaj.org/article/917c54f7881d431788d492095569abd1
Formal group insertion into aryl C‒N bonds through an aromaticity destruction-reconstruction process
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Activation of C–N bonds of anilines requires transformation of the amino group into a more reactive functionality. Here, the authors report an aromaticity destruction-reconstruction process that converts abundant anilines into valuable amines throu
Externí odkaz:
https://doaj.org/article/64f27b6d50a24572affe783994d2b747
Publikováno v:
Organic Letters. 24:2665-2669
A process for the synthesis of C7-functionalized indoles using para-substituted 2-alkynylanilines as starting materials was reported. The process involves a dearomatization, an 1,2-addition by organic lithium or Grignard reagents, an aromatization-dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f952daff726706b0f7f3f4a8bd663bd
https://doi.org/10.1021/acs.orglett.2c00733
https://doi.org/10.1021/acs.orglett.2c00733
Publikováno v:
Organic Chemistry Frontiers. 9:4146-4150
A dearomatization method for divergent synthesis of 4-amino indoles having N1 or C4 free amine groups from 2-alkynylanilines was reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eccdeb635ce4de58d5f97d3c9cf2ecdc
https://doi.org/10.1039/d2qo00675h
https://doi.org/10.1039/d2qo00675h
Publikováno v:
Organic Letters. 24:314-318
A method for stereoselective construction of acyclic all-carbon tetrasubstituted alkenes through insertion of nitrile-substituted trimethylenemethane into the aryl C-N bond in anilines via an aromaticity destruction-reconstruction process is reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad265ef75733f15ffa7103a4f3cade6
https://doi.org/10.1021/acs.orglett.1c03974
https://doi.org/10.1021/acs.orglett.1c03974
Publikováno v:
Organic Chemistry Frontiers. 8:6869-6873
A one-pot stepwise procedure for the synthesis of N-indolated amino acids or peptides from readily available 2-alkynylanilines was reported. The protocol involves the oxidative dearomatization of 2-alkynylanilines, the imino exchange with aliphatic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::221f5ad613ace8e400ebdc32d5b565dd
https://doi.org/10.1039/d1qo01257f
https://doi.org/10.1039/d1qo01257f
Publikováno v:
Chemical Communications. 57:5442-5445
A nitrogen replacement process that directly incorporates the 15N atom of glycine-15N into anilines was reported. The process involves a Csp2–N bond cleavage of anilines driven by dearomatization and a Csp3–N bond cleavage of glycine-15N driven b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c14243856d5404317dfdea7ecac5055
https://doi.org/10.1039/d1cc01734a
https://doi.org/10.1039/d1cc01734a
Publikováno v:
Organic Chemistry Frontiers. 8:3004-3007
A process for rapid synthesis of 4-acetoxyindoles from readily available 2-alkynylanilines was reported. The process involves an oxidative dearomatization and subsequent cascade nucleophilic addition/cyclization/aromatization. A range of functional g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44eb13b383127b91ade6e5d4ee5a0954
https://doi.org/10.1039/d1qo00358e
https://doi.org/10.1039/d1qo00358e
Publikováno v:
Chemical communications (Cambridge, England). 58(48)
An anodic oxidative dearomatization reaction of 2-alkynylanilines was developed. The formed dearomatized compounds were used as versatile precursors in the synthesis of a variety of benzenoid ring multi-functionalized indoles through simple conversio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0db7229df74f977d8e3e1cb34d6ac6
https://pubmed.ncbi.nlm.nih.gov/35611853
https://pubmed.ncbi.nlm.nih.gov/35611853