Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Rengul Cetin-Atalay"'
Autor:
Rengul Cetin-Atalay, Angelo Y. Meliton, Kaitlyn A. Sun, Mariel E. Glass, Parker S. Woods, Ying-Jie Peng, Yun Fang, Robert B. Hamanaka, Nanduri R. Prabhakar, Gökhan M. Mutlu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular disease. While intermittent hypoxia (IH) and catecholamine release play an important role in this increased risk, the mechanisms are incompletely understood. We h
Externí odkaz:
https://doaj.org/article/78a6903cbc554691bb1bab10ab7d2575
Autor:
Rengul Cetin-Atalay, Angelo Y Meliton, Cevher Ozcan, Parker S Woods, Kaitlyn A Sun, Yun Fang, Robert B Hamanaka, Gökhan M Mutlu
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292990 (2023)
Obstructive sleep apnea (OSA) is a common breathing disorder that affects a significant portion of the adult population. In addition to causing excessive daytime sleepiness and neurocognitive effects, OSA is an independent risk factor for cardiovascu
Externí odkaz:
https://doaj.org/article/bfff69ee5b4140b0b44df98907b762f2
Autor:
Mohammed Hawash, Deniz Cansen Kahraman, Sezen Guntekin Ergun, Rengul Cetin-Atalay, Sultan Nacak Baytas
Publikováno v:
BMC Chemistry, Vol 15, Iss 1, Pp 1-14 (2021)
Abstract Background Liver cancer is predicted to be the sixth most diagnosed cancer globally and fourth leading cause of cancer deaths. In this study, a series of indole-3-isoxazole-5-carboxamide derivatives were designed, synthesized, and evaluated
Externí odkaz:
https://doaj.org/article/5babdee60f4d4b078a7393ea07b9214d
Autor:
Murat Erdem, İbrahim Ozgul, Didem Naz Dioken, Irmak Gurcuoglu, Sezen Guntekin Ergun, Rengul Cetin-Atalay, Tolga Can, Ayse Elif Erson-Bensan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Roles of HNRNPA1 are beginning to emerge in cancers; however, mechanisms causing deregulation of HNRNPA1 function remain elusive. Here, we describe an isoform switch between the 3′-UTR isoforms of HNRNPA1 in breast cancers. We show that th
Externí odkaz:
https://doaj.org/article/bd105dc456f04a9b967fd9a19f1e036d
Autor:
Tunca Doğan, Ece Akhan Güzelcan, Marcus Baumann, Altay Koyas, Heval Atas, Ian R Baxendale, Maria Martin, Rengul Cetin-Atalay
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 11, p e1009171 (2021)
Predictive approaches such as virtual screening have been used in drug discovery with the objective of reducing developmental time and costs. Current machine learning and network-based approaches have issues related to generalization, usability, or m
Externí odkaz:
https://doaj.org/article/300998f38bfd495a97aea9c262e40130
Autor:
Rengul Cetin-Atalay, Angelo Y. Meliton, David Wu, Parker S. Woods, Kaitlyn A. Sun, Ying-Jie Peng, Jayasri Nanduri, Xiaoyu Su, Yun Fang, Robert B. Hamanaka, Nanduri Prabhakar, Gökhan M. Mutlu
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Obstructive sleep apnea (OSA) is a common breathing disorder affecting a significant percentage of the adult population. OSA is an independent risk factor for cardiovascular disease (CVD); however, the underlying mechanisms are not completely underst
Externí odkaz:
https://doaj.org/article/b9c692b18c724b9f9e6edc007e2175e8
Autor:
Alperen Dalkiran, Ahmet Sureyya Rifaioglu, Maria Jesus Martin, Rengul Cetin-Atalay, Volkan Atalay, Tunca Doğan
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background The automated prediction of the enzymatic functions of uncharacterized proteins is a crucial topic in bioinformatics. Although several methods and tools have been proposed to classify enzymes, most of these studies are limited to
Externí odkaz:
https://doaj.org/article/b99d8a4b09534f78a2529ea118214ae3
Publikováno v:
IEEE Access, Vol 6, Pp 3839-3850 (2018)
Contrast enhancement is an important preprocessing step for the analysis of microscopy images. The main aim of contrast enhancement techniques is to increase the visibility of the cell structures and organelles by modifying the spatial characteristic
Externí odkaz:
https://doaj.org/article/124688c2a2ec42418ecf1cd1dd518d4d
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93341 (2014)
Transcriptome experiments are performed to assess protein abundance through mRNA expression analysis. Expression levels of genes vary depending on the experimental conditions and the cell response. Transcriptome data must be diverse and yet comparabl
Externí odkaz:
https://doaj.org/article/400b651814f04370a98ea2a5f93d0b6c
Autor:
Furkan Keskin, Alexander Suhre, Kivanc Kose, Tulin Ersahin, A Enis Cetin, Rengul Cetin-Atalay
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e52807 (2013)
Cancer cell lines are widely used for research purposes in laboratories all over the world. Computer-assisted classification of cancer cells can alleviate the burden of manual labeling and help cancer research. In this paper, we present a novel compu
Externí odkaz:
https://doaj.org/article/c697cb1560cb4c549b36454835c89f65