Zobrazeno 1 - 10
of 286
pro vyhledávání: '"Rengul Cetin‐Atalay"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9392 (2024)
Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer, with a high mortality rate due to the limited therapeutic options. Systemic drug treatments improve the patient’s life expectancy by only a few months. Furthermore, the deve
Externí odkaz:
https://doaj.org/article/fcd045dca8c542c7a4615b44521ed611
Autor:
Rengul Cetin-Atalay, Angelo Y. Meliton, Kaitlyn A. Sun, Mariel E. Glass, Parker S. Woods, Ying-Jie Peng, Yun Fang, Robert B. Hamanaka, Nanduri R. Prabhakar, Gökhan M. Mutlu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular disease. While intermittent hypoxia (IH) and catecholamine release play an important role in this increased risk, the mechanisms are incompletely understood. We h
Externí odkaz:
https://doaj.org/article/78a6903cbc554691bb1bab10ab7d2575
Autor:
Deniz Cansen Kahraman, Ebru Bilget Guven, Peri S. Aytac, Gamze Aykut, Birsen Tozkoparan, Rengul Cetin Atalay
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Hepatocellular carcinoma (HCC) is a highly heterogeneous cancer, and resistant to both conventional and targeted chemotherapy. Recently, nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to decrease the incidence and mortality of
Externí odkaz:
https://doaj.org/article/de9102c153df4f01a413d6729442aabf
Autor:
Rengul Cetin-Atalay, Angelo Y Meliton, Cevher Ozcan, Parker S Woods, Kaitlyn A Sun, Yun Fang, Robert B Hamanaka, Gökhan M Mutlu
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292990 (2023)
Obstructive sleep apnea (OSA) is a common breathing disorder that affects a significant portion of the adult population. In addition to causing excessive daytime sleepiness and neurocognitive effects, OSA is an independent risk factor for cardiovascu
Externí odkaz:
https://doaj.org/article/bfff69ee5b4140b0b44df98907b762f2
Autor:
Kubra Narci, Deniz Cansen Kahraman, Altay Koyas, Tulin Ersahin, Nurcan Tuncbag, Rengul Cetin Atalay
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Targeted therapies for Primary liver cancer (HCC) is limited to the multi-kinase inhibitors, and not fully effective due to the resistance to these agents because of the heterogeneous molecular nature of HCC developed during chron
Externí odkaz:
https://doaj.org/article/53ad61d884cb456592996e5ace0b2e78
Autor:
Mohammed Hawash, Deniz Cansen Kahraman, Sezen Guntekin Ergun, Rengul Cetin-Atalay, Sultan Nacak Baytas
Publikováno v:
BMC Chemistry, Vol 15, Iss 1, Pp 1-14 (2021)
Abstract Background Liver cancer is predicted to be the sixth most diagnosed cancer globally and fourth leading cause of cancer deaths. In this study, a series of indole-3-isoxazole-5-carboxamide derivatives were designed, synthesized, and evaluated
Externí odkaz:
https://doaj.org/article/5babdee60f4d4b078a7393ea07b9214d
Autor:
Murat Erdem, İbrahim Ozgul, Didem Naz Dioken, Irmak Gurcuoglu, Sezen Guntekin Ergun, Rengul Cetin-Atalay, Tolga Can, Ayse Elif Erson-Bensan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Roles of HNRNPA1 are beginning to emerge in cancers; however, mechanisms causing deregulation of HNRNPA1 function remain elusive. Here, we describe an isoform switch between the 3′-UTR isoforms of HNRNPA1 in breast cancers. We show that th
Externí odkaz:
https://doaj.org/article/bd105dc456f04a9b967fd9a19f1e036d
Publikováno v:
Journal of Imaging, Vol 9, Iss 2, p 25 (2023)
This paper proposes a new Hepatocellular Carcinoma (HCC) classification method utilizing a hyperspectral imaging system (HSI) integrated with a light microscope. Using our custom imaging system, we have captured 270 bands of hyperspectral images of h
Externí odkaz:
https://doaj.org/article/3ed18254726f4d368104a4c4cf43dcf8
Publikováno v:
Acta Chimica Slovenica, Vol 67, Iss 1, Pp 70-82 (2020)
A series of new 6,9-disubstituted purine analogs with 4-substituted piperazine at C-6 and 4-substituted benzyl at N-9 were designed and synthesized in four steps. All synthesized compounds (7–26) were screened initially for their in vitro anticance
Externí odkaz:
https://doaj.org/article/1d0121fd63c6498eae381fa41e8547f4
Autor:
Naihui Zhou, Yuxiang Jiang, Timothy R. Bergquist, Alexandra J. Lee, Balint Z. Kacsoh, Alex W. Crocker, Kimberley A. Lewis, George Georghiou, Huy N. Nguyen, Md Nafiz Hamid, Larry Davis, Tunca Dogan, Volkan Atalay, Ahmet S. Rifaioglu, Alperen Dalkıran, Rengul Cetin Atalay, Chengxin Zhang, Rebecca L. Hurto, Peter L. Freddolino, Yang Zhang, Prajwal Bhat, Fran Supek, José M. Fernández, Branislava Gemovic, Vladimir R. Perovic, Radoslav S. Davidović, Neven Sumonja, Nevena Veljkovic, Ehsaneddin Asgari, Mohammad R.K. Mofrad, Giuseppe Profiti, Castrense Savojardo, Pier Luigi Martelli, Rita Casadio, Florian Boecker, Heiko Schoof, Indika Kahanda, Natalie Thurlby, Alice C. McHardy, Alexandre Renaux, Rabie Saidi, Julian Gough, Alex A. Freitas, Magdalena Antczak, Fabio Fabris, Mark N. Wass, Jie Hou, Jianlin Cheng, Zheng Wang, Alfonso E. Romero, Alberto Paccanaro, Haixuan Yang, Tatyana Goldberg, Chenguang Zhao, Liisa Holm, Petri Törönen, Alan J. Medlar, Elaine Zosa, Itamar Borukhov, Ilya Novikov, Angela Wilkins, Olivier Lichtarge, Po-Han Chi, Wei-Cheng Tseng, Michal Linial, Peter W. Rose, Christophe Dessimoz, Vedrana Vidulin, Saso Dzeroski, Ian Sillitoe, Sayoni Das, Jonathan Gill Lees, David T. Jones, Cen Wan, Domenico Cozzetto, Rui Fa, Mateo Torres, Alex Warwick Vesztrocy, Jose Manuel Rodriguez, Michael L. Tress, Marco Frasca, Marco Notaro, Giuliano Grossi, Alessandro Petrini, Matteo Re, Giorgio Valentini, Marco Mesiti, Daniel B. Roche, Jonas Reeb, David W. Ritchie, Sabeur Aridhi, Seyed Ziaeddin Alborzi, Marie-Dominique Devignes, Da Chen Emily Koo, Richard Bonneau, Vladimir Gligorijević, Meet Barot, Hai Fang, Stefano Toppo, Enrico Lavezzo, Marco Falda, Michele Berselli, Silvio C.E. Tosatto, Marco Carraro, Damiano Piovesan, Hafeez Ur Rehman, Qizhong Mao, Shanshan Zhang, Slobodan Vucetic, Gage S. Black, Dane Jo, Erica Suh, Jonathan B. Dayton, Dallas J. Larsen, Ashton R. Omdahl, Liam J. McGuffin, Danielle A. Brackenridge, Patricia C. Babbitt, Jeffrey M. Yunes, Paolo Fontana, Feng Zhang, Shanfeng Zhu, Ronghui You, Zihan Zhang, Suyang Dai, Shuwei Yao, Weidong Tian, Renzhi Cao, Caleb Chandler, Miguel Amezola, Devon Johnson, Jia-Ming Chang, Wen-Hung Liao, Yi-Wei Liu, Stefano Pascarelli, Yotam Frank, Robert Hoehndorf, Maxat Kulmanov, Imane Boudellioua, Gianfranco Politano, Stefano Di Carlo, Alfredo Benso, Kai Hakala, Filip Ginter, Farrokh Mehryary, Suwisa Kaewphan, Jari Björne, Hans Moen, Martti E.E. Tolvanen, Tapio Salakoski, Daisuke Kihara, Aashish Jain, Tomislav Šmuc, Adrian Altenhoff, Asa Ben-Hur, Burkhard Rost, Steven E. Brenner, Christine A. Orengo, Constance J. Jeffery, Giovanni Bosco, Deborah A. Hogan, Maria J. Martin, Claire O’Donovan, Sean D. Mooney, Casey S. Greene, Predrag Radivojac, Iddo Friedberg
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-23 (2019)
Abstract Background The Critical Assessment of Functional Annotation (CAFA) is an ongoing, global, community-driven effort to evaluate and improve the computational annotation of protein function. Results Here, we report on the results of the third C
Externí odkaz:
https://doaj.org/article/4c2b017b155b41ceab8d6d078186cafa