Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Renfa Lai"'
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24906- (2024)
Objective: Osteoporosis is a common clinical bone disease that occurs most frequently in middle-aged and elderly people. Various traditional herbal medicine formulations have shown significant benefits in models of osteoporosis. In this study, we aim
Externí odkaz:
https://doaj.org/article/4364289f352f44a893b27ecdc313371d
Publikováno v:
npj Science of Food, Vol 6, Iss 1, Pp 1-10 (2022)
Abstract Rheumatoid arthritis (RA) seriously impairs the quality of life of sufferers. It has been shown that Lycium barbarum polysaccharide (LBP), a natural active indigestible ingredient with medicinal and edible functions, can effectively relieve
Externí odkaz:
https://doaj.org/article/e3e68d05c241432a9e6001781fa70617
Autor:
Fujun Jin, Junhui Li, Yong-Biao Zhang, Xiangning Liu, Mingxiang Cai, Meijing Liu, Mengyao Li, Cui Ma, Rui Yue, Yexuan Zhu, Renfa Lai, Zuolin Wang, Xunming Ji, Huawei Wei, Jun Dong, Zhiduo Liu, Yifei Wang, Yao Sun, Xiaogang Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
LncRNAs are implicated in the pathogenesis of a number of diseases. Here, the authors show that the lncRNA Nron suppresses bone resorption, and show that delivery of a functional motif of Nron increases bone mass in mouse models of osteoporosis.
Externí odkaz:
https://doaj.org/article/2db4d2d2e3084d188c632108a8a430b0
Autor:
Ting Sun, Yiyuan Kang, Jia Liu, Yanli Zhang, Lingling Ou, Xiangning Liu, Renfa Lai, Longquan Shao
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-23 (2021)
Abstract The widespread use of nanomaterials (NMs) has raised concerns that exposure to them may introduce potential risks to the human body and environment. The liver is the main target organ for NMs. Hepatotoxic effects caused by NMs have been obse
Externí odkaz:
https://doaj.org/article/b4e3037403e84433a72cf314a3b4bbc8
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 101013- (2021)
MicroRNAs (miRNAs) have been proven to serve as key post-transcriptional regulators, affecting diverse biological processes including osteogenic differentiation and bone formation. Recently, it has been reported that miR-146a-5p affects the activity
Externí odkaz:
https://doaj.org/article/95958e10895f4c28bc86fe25c0d16402
Publikováno v:
Nanoscale Research Letters, Vol 13, Iss 1, Pp 1-8 (2018)
Abstract ᅟ A graded nano-glass/zirconia (G/Z) system has been developed via the infiltration of nano-glass into a nano-zirconia surface, which is advantageous for robust core-veneer bonds. The aging issue is a key for yttrium-stabilized tetragonal
Externí odkaz:
https://doaj.org/article/54a4c83fa5c547ae82b1fc201eb06bf9
Publikováno v:
Heliyon, Vol 4, Iss 7, Pp e00662- (2018)
Objectives: The aims of this study were to create a new surface topography using simulated body fluids (SBF) and Gold Nanoparticles (GNPs) and then to assess the influence of UV Photofunctionalization (PhF) on the osteogenic capacity of these surface
Externí odkaz:
https://doaj.org/article/b2196e65cc4e4c048e0271312ce664e7
Publikováno v:
Process Safety and Environmental Protection. 147:134-145
Zirconia nanoparticles (ZrO2-NPs) have been increasingly used in industrial, biomedical and dental materials. Nevertheless, the scientific basis for the toxicological effects of ZrO2-NPs is poorly elucidated, and the understanding of the underlying m
Publikováno v:
Bioengineered, Vol 12, Iss 1, Pp 2164-2174 (2021)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
Oral squamous cell carcinoma (OSCC) is the most common tumor of the oral cavity. Studies have shown that exosomal miRNAs from cancer cells play an important role in mediating the cellular environment. The objective was to investigate the effect of OS
Autor:
Jie Yao, Yayu Wang, Xiaogang Wang, Cai Lizhao, Tong Liu, Ye Zhang, Xiangning Liu, Minyi Liu, Zhiying Zhou, Renfa Lai, Tingwei Li
Publikováno v:
International Journal of Nanomedicine. 15:7967-7977
Background Current drugs used for osteoporosis therapy show strong adverse effects. Stem cell-derived extracellular vesicles (EVs) provide another choice for osteoporosis therapy. Mouse mesenchymal stem cells (mMSCs)-derived EVs promote bone regenera