Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Renee X de Menezes"'
Autor:
Iris E Glykofridis, Jaco C Knol, Jesper A Balk, Denise Westland, Thang V Pham, Sander R Piersma, Sinéad M Lougheed, Sepide Derakhshan, Puck Veen, Martin A Rooimans, Saskia E van Mil, Franziska Böttger, Pino J Poddighe, Irma van de Beek, Jarno Drost, Fried JT Zwartkruis, Renee X de Menezes, Hanne EJ Meijers-Heijboer, Arjan C Houweling, Connie R Jimenez, Rob MF Wolthuis
Publikováno v:
eLife, Vol 10 (2021)
Germline mutations in the Folliculin (FLCN) tumor suppressor gene cause Birt–Hogg–Dubé (BHD) syndrome, a rare autosomal dominant disorder predisposing carriers to kidney tumors. FLCN is a conserved, essential gene linked to diverse cellular proc
Externí odkaz:
https://doaj.org/article/afeb46d1c35540eaa522d75e244c66bd
Autor:
Joana Amado-Azevedo, Renee X de Menezes, Geerten P van Nieuw Amerongen, Victor W M van Hinsbergh, Peter L Hordijk
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201231 (2018)
Thrombin and other inflammatory mediators may induce vascular permeability through the disruption of adherens junctions between adjacent endothelial cells. If uncontrolled, hyperpermeability leads to an impaired barrier, fluid leakage and edema, whic
Externí odkaz:
https://doaj.org/article/042b282c839c4993a979d1b359e5f8cd
Predictive gene expression profile for adjuvant taxane benefit in breast cancer in the MATADOR trial
Autor:
Mark Opdam, Annelot G.J. van Rossum, Marlous Hoogstraat, Gergana Bounova, Hugo M. Horlings, Erik van Werkhoven, Ingrid A.M. Mandjes, A. Elise van Leeuwen – Stok, Sander Canisius, Harm van Tinteren, Alex L.T. Imholz, Johanneke E.A. Portielje, Monique E.M.M. Bos, Sandra Bakker, Jelle Wesseling, Lennart Kester, Jacco van Rheenen, Emiel J. Rutgers, Renee X. de Menezes, Lodewyk F.A. Wessels, Marleen Kok, Hendrika M. Oosterkamp, Sabine C. Linn, Marcel Soesan, Rianne M. Oosterkamp, Frank Jeurissen, Nir Weijl, Karin J. Beelen, Aart van Bochove, Gerty de Klerk, Suzan Vrijaldenhoven, Annette van der Velden, Hiltje de Graaf, Marielle Smeets, Jetske Meerum Terwogt, Jolanda Schrama, Philomeen Kuijer, Hanneke Wilmink, Ronald Hoekstra, Judith Kroep, Hans F.M. Pruijt, Leander van Gerven, Allert H. Vos, Frans Erdkamp, Willemien G. van Leeuwen-Breuk, Alexander de Graeff
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110425- (2024)
Summary: The primary objective of the prospective, randomized, multicenter, phase 3 biomarker Microarray Analysis in breast cancer to Taylor Adjuvant Drugs Or Regimens trial (MATADOR: ISRCTN61893718) is to generate a gene expression profile that can
Externí odkaz:
https://doaj.org/article/3dae747c44804a5fafa1281b33a3c21c
Autor:
Anke A Dijkstra, Angela Ingrassia, Renee X de Menezes, Ronald E van Kesteren, Annemieke J M Rozemuller, Peter Heutink, Wilma D J van de Berg
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128651 (2015)
Subjects with incidental Lewy body disease (iLBD) may represent the premotor stage of Parkinson's disease (PD). To elucidate molecular mechanisms underlying neuronal dysfunction and alpha-synuclein pathology in the premotor phase of PD, we investigat
Externí odkaz:
https://doaj.org/article/b5e30979bec14397a3460408e3e1a934
Autor:
Govind Pai, Khashayar Roohollahi, Davy Rockx, Yvonne de Jong, Chantal Stoepker, Charlotte Pennings, Martin Rooimans, Lianne Vriend, Sander Piersma, Connie R. Jimenez, Renee X. De Menezes, Victor W. Van Beusechem, Ruud H. Brakenhoff, Hein Te Riele, Rob M. F. Wolthuis, Josephine C. Dorsman
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
A genome-wide siRNA screen on patient-derived Fanconi anemia pathway-deficient head-and-neck squamous-cell-carcinoma (HNSCC) cell lines identifies RBBP9 as a candidate therapeutic target.
Externí odkaz:
https://doaj.org/article/d4abaadf82fc4ce89a966aaa06a906bf
Autor:
Emanuela Felley-Bosco, Victor W. van Beusechem, Lorenza Penengo, Rolf A. Stahel, Walter Weder, Egbert F. Smit, Kathrin Oehl, Martin Wipplinger, Renee X. de Menezes, Ida H. van der Meulen-Muileman, Maxime Blijlevens, Manuel Ronner, Vasundhara Rao, Saskja Bühler, Agata Okonska
Supplementary Fig. S1: Characterization of the model used for whole genome silencing, individual screen lethality scores and list of candidate genes with differential lethality scores ; Supplementary Fig. S2: Validation of the RRM1 and RRM2 knockdown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605ff950fc1c5dce74ce496371b31574
https://doi.org/10.1158/1535-7163.22505877.v1
https://doi.org/10.1158/1535-7163.22505877.v1
Autor:
Riccardo Fodde, Judith M. Boer, Hans Morreau, Julian Sampson, Gabriela Möslein, Carla Rosenberg, Monique van Leerdam, Renee X. de Menezes, Lia Molenaar, Joana Cardoso
The vast majority of colorectal cancers display genetic instability, either in the chromosomal instability (CIN) or microsatellite instability (MIN) forms. Although CIN tumors are per definition aneuploid, MIN colorectal cancers, caused by loss of mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a3eac26717692dbd503384673ae4ec
https://doi.org/10.1158/0008-5472.c.6494952
https://doi.org/10.1158/0008-5472.c.6494952
Autor:
Riccardo Fodde, Judith M. Boer, Hans Morreau, Julian Sampson, Gabriela Möslein, Carla Rosenberg, Monique van Leerdam, Renee X. de Menezes, Lia Molenaar, Joana Cardoso
Supplementary Table 1 from Chromosomal Instability in MYH- and APC-Mutant Adenomatous Polyps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ea3c010fd5e2c73f5960f5be2ba27c
https://doi.org/10.1158/0008-5472.22366014.v1
https://doi.org/10.1158/0008-5472.22366014.v1
Publikováno v:
Biometrical Journal, 65
Biometrical Journal, 65, 1
Biometrical Journal, 65, 1
Contains fulltext : 291396.pdf (Publisher’s version ) (Closed access) Statistical methods to test for effects of single nucleotide polymorphisms (SNPs) on exon inclusion exist but often rely on testing of associations between multiple exon-SNP pair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d418693236c5e772033c5afd6a74bc23
https://doi.org/10.1002/bimj.202100123
https://doi.org/10.1002/bimj.202100123
Autor:
Marc Vila Cuenca, Evelina Ferrantelli, Elisa Meinster, Stephan M. Pouw, Igor Kovačević, Renee X. de Menezes, Hans W. Niessen, Robert H.J. Beelen, Peter L. Hordijk, Marc G. Vervloet
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 17 (2018)
Background Dysfunctional endothelium may contribute to the development of cardiovascular complications in chronic kidney disease (CKD). Supplementation with active vitamin D has been proposed to have vasoprotective potential in CKD, not only by direc
Externí odkaz:
https://doaj.org/article/6125b4404ece47069e715d53250e83b3