Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Renee Whan"'
Autor:
Liam Johnson, Florence Bartlett-Tomasetig, Sandra Fok, Renee Whan, Joel Berliner, Sarah J. Hemley, Marcus A. Stoodley, Lynne E. Bilston
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Posttraumatic syringomyelia (PTS) is an enigmatic condition characterized by the development of fluid-filled cysts (syrinxes) within the spinal cord. Perivascular spaces (PVS) are a critical component of fluid transport within the central ne
Externí odkaz:
https://doaj.org/article/c9bcfa856999449382b6d5637038d5ca
Autor:
Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background Metastatic cancer cells exploit Epithelial-mesenchymal-transition (EMT) to enhance their migration, invasion, and resistance to treatments. Recent studies highlight that elevated levels of copper are implicated in cancer progressi
Externí odkaz:
https://doaj.org/article/b17391f9a29d4891bcdc6914896812f8
Autor:
James Wang, Lois Browne, Iveta Slapetova, Fei Shang, Kirsty Lee, Jodi Lynch, Julia Beretov, Renee Whan, Peter H. Graham, Ewan K. A. Millar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Triple negative breast cancer (TNBC) comprises 10–15% of all breast cancers and has a poor prognosis with a high risk of recurrence within 5 years. PD-L1 is an important biomarker for patient selection for immunotherapy but its cellular ex
Externí odkaz:
https://doaj.org/article/34c61617586b40f799dbf32a01b62a1c
Autor:
Mijeong Park, Alexander Richardson, Elvis Pandzic, Erwin P. Lobo, Renee Whan, Stephanie L. Watson, J. Guy Lyons, Denis Wakefield, Nick Di Girolamo
Publikováno v:
Stem Cell Reports, Vol 12, Iss 1, Pp 14-28 (2019)
Summary: It is thought that corneal epithelial injuries resolve by leading-edge cells “sliding” or “rolling” into the wound bed. Here, we challenge this notion and show by real-time imaging that corneal wounds initially heal by “basal cell
Externí odkaz:
https://doaj.org/article/d5ad1a27982e4dfa9e43c6206adbecad
Autor:
Vina D. L. Putra, Min Jae Song, Sarah McBride-Gagyi, Hana Chang, Kate Poole, Renee Whan, David Dean, Vittorio Sansalone, Melissa L. Knothe Tate
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2020)
Mechanomics represents the natural progression of knowledge at the intersection of mechanics and biology with the aim to codify the role of mechanical environment on biological adaptation. Compared to the mapping of the human genome, the challenge of
Externí odkaz:
https://doaj.org/article/72c239d541c147b6b0a757ecbf5510c4
Autor:
Vina Putra, Iman Jalilian, Madeline Campbell, Kate Poole, Renee Whan, Florence Tomasetig, Melissa Knothe Tate
Publikováno v:
Bio-Protocol, Vol 9, Iss 23 (2019)
Mechanomics, the mechanics equivalent of genomics, is a burgeoning field studying mechanical modulation of stem cell behavior and lineage commitment. Analogous to mechanical testing of a living material as it adapts and evolves, mapping of the mechan
Externí odkaz:
https://doaj.org/article/cb2296df83c548109ff16a6e7fb337e3
Autor:
Ewan Millar, Lois Browne, Iveta Slapetova, Fei Shang, Yuqi Ren, Rachel Bradshaw, Heather Ann Brauer, Sandra O’Toole, Julia Beretov, Renee Whan, Peter H. Graham
Publikováno v:
Cancers, Vol 12, Iss 9, p 2365 (2020)
Aim: To determine the prognostic significance of the immunophenotype of tumour-infiltrating lymphocytes (TILs) within a cohort of breast cancer patients with long-term follow-up. Methods: Multiplexed immunofluorescence and automated image analysis we
Externí odkaz:
https://doaj.org/article/15e41f9b6a7b4a7082ae111ea1278207
Autor:
Ivan Lukmantara, Fang Chen, Hoi Yin Mak, Armella Zadoorian, Ximing Du, Fanqian Nicole Xiao, Dougall MacMurray Norris, Elvis Pandzic, Renee Whan, Qing Zhong, Hongyuan Yang
Publikováno v:
Molecular Biology of the Cell. 33
The biogenesis of lipid droplets (LDs), key organelles for cellular lipid storage and homeostasis, remains poorly understood. Seipin is essential to normal LD biogenesis but exactly how it regulates LD initiation remains to be elucidated. Our previou
The microtubule protein, βIII-tubulin, has been implicated as a prognostic, pro-survival, and chemoresistance factor in some of the most lethal malignancies including pancreatic ductal adenocarcinoma (PDAC). However, precise survival mechanisms cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cab4ad6e35a240079b2088fce4968df2
https://doi.org/10.1101/2022.09.29.510034
https://doi.org/10.1101/2022.09.29.510034
Autor:
Elvis Pandzic, Nihan Turgutoglu, Iveta Slapetova, Renee Whan, Sharon L. Wong, Ling Zhong, Shafagh A. Waters, Adam Jaffe, Nikhil T. Awatade, Laura K. Fawcett, Alexander Capraro
Publikováno v:
Journal of Cystic Fibrosis. 20:364-371
Background Patient-derived airway cells differentiated at Air Liquid Interface (ALI) are valuable models for Cystic fibrosis (CF) precision therapy. Different culture expansion methods have been established to extend expansion capacity of airway basa