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pro vyhledávání: '"Renee R. Hood"'
Autor:
Renee R Hood, Eric L Kendall, Mariana Junqueira, Wyatt N Vreeland, Zenaide Quezado, Julia C Finkel, Don L DeVoe
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92978 (2014)
Microfluidic synthesis of small and nearly-monodisperse liposomes is used to investigate the size-dependent passive transdermal transport of nanoscale lipid vesicles. While large liposomes with diameters above 105 nm are found to be excluded from dee
Externí odkaz:
https://doaj.org/article/19096eca9934424abf2ebcf95e96016b
Publikováno v:
Sensors and Actuators B: Chemical. 220:992-999
The integration of multibarrel glass capillaries into a microfluidic co-flow configuration is demonstrated for parallel production of nanoliter scale droplets. The multibarrel system supports the generation of a continuous stream of single-phase or d
Autor:
Renee R. Hood, Don L. DeVoe
Publikováno v:
Small. 11:5790-5799
Liposomes represent a leading class of nanoparticles for drug delivery. While a variety of techniques for liposome synthesis have been reported that take advantage of microfluidic flow elements to achieve precise control over the size and polydispers
Publikováno v:
Pharmaceutical Research. 31:401-413
This study investigates the cellular uptake and trafficking of liposomes in Caco-2 cells, using vesicles with distinct average diameters ranging from 40.6 nm to 276.6 nm. Liposomes were prepared by microfluidic hydrodynamic flow focusing, producing n
Publikováno v:
Pharmaceutical Research. 30:1597-1607
A microfluidic hydrodynamic flow focusing technique enabling the formation of small and nearly monodisperse liposomes is investigated for continuous-flow synthesis of poly(ethylene glycol) (PEG)-modified and PEG-folate-functionalized liposomes for ta
Publikováno v:
Lab on a chip. 14(17)
Microfluidic-directed formation of liposomes is combined with in-line sample purification and remote drug loading for single step, continuous-flow synthesis of nanoscale vesicles containing high concentrations of stably loaded drug compounds. Using a
Publikováno v:
Lab on a chip. 14(14)
A novel microscale device has been developed to enable the one-step continuous flow assembly of monodisperse nanoscale liposomes using three-dimensional microfluidic hydrodynamic focusing (3D-MHF) in a concentric capillary array. The 3D-MHF flow tech
Autor:
Zenaide M.N. Quezado, Don L. DeVoe, Wyatt N. Vreeland, Julia C. Finkel, Eric L. Kendall, Mariana Junqueira, Renee R. Hood
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 3, p e92978 (2014)
PLoS ONE, Vol 9, Iss 3, p e92978 (2014)
Microfluidic synthesis of small and nearly-monodisperse liposomes is used to investigate the size-dependent passive transdermal transport of nanoscale lipid vesicles. While large liposomes with diameters above 105 nm are found to be excluded from dee
Autor:
Mariana Junqueira, Zenaide M.N. Quezado, Julia C. Finkel, Eric L. Kendall, Don L. DeVoe, Wyatt N. Vreeland, Renee R. Hood
Publikováno v:
2013 Microsystems for Measurement and Instrumentation: Fulfilling the Promise (MAMNA).
In this work, the established technique for microfluidic synthesis of nanoscale liposomes of tunable size has been exploited for preclinical studies investigating the ability of small liposomes to passively cross through dermal layers for transdermal
Autor:
Abhay Andar, Peter W. Swaan, Don L. DeVoe, Donna M. Omiatek, Renee R. Hood, Wyatt N. Vreeland
Publikováno v:
2012 Microsystems for Measurement and Instrumentation (MAMNA).
In this study, we extend the technique of the production of small and nearly-monodisperse liposomes using a formerly demonstrated microfluidic hydrodynamic focusing technique toward the continuous-flow synthesis of poly(ethylene glycol) (PEG)-modifie