Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Renee M. Zaya"'
Autor:
Suvit Thaisrivongs, Harvey I. Skulnick, Steve R. Turner, Joseph W. Strohbach, Ruben A. Tommasi, Paul D. Johnson, Paul A. Aristoff, Thomas M. Judge, Ronald B. Gammill, Jeanette K. Morris, Karen R. Romines, Robert A. Chrusciel, Roger R. Hinshaw, Kong-Teck Chong, W. Gary Tarpley, Susan M. Poppe, David E. Slade, Janet C. Lynn, Miao-Miao Horng, Paul K. Tomich, Eric P. Seest, Lester A. Dolak, W. Jeffrey Howe, Gina M. Howard, Francis J. Schwende, Lisa N. Toth, Guy E. Padbury, Grace J. Wilson, Lihua Shiou, Gail L. Zipp, Karen F. Wilkinson, Bob D. Rush, Mary J. Ruwart, Kenneth A. Koeplinger, Zhiyang Zhao, Serena Cole, Renee M. Zaya, Thomas J. Kakuk, Musiri N. Janakiraman, Keith D. Watenpaugh
Publikováno v:
Journal of Medicinal Chemistry. 39:4349-4353
Publikováno v:
Pharmaceutical Research. :80-83
Ditekiren is a pseudo-octapeptide being developed as an inhibitor of human renin. Preclinical drug safety studies with this drug involved continuous iv infusions through indwelling catheters in the right internal jugular vein of the cynomolgus monkey
Autor:
G.L Zipp, Lester A. Dolak, K. D. Watenpaugh, W.-Z Zhong, R. R. Hinshaw, C.W Johnson, David J. Anderson, L. S. Banitt, Johnson Paul D, Paul A. Aristoff, G.M Howard, M.N. Janakiraman, R J Reischer, Howe Wj, Harvey Irving Skulnick, Theresa M. Schwartz, L. N. Toth, K.R Wilkinson, Bob D. Rush, Karen Rene Romines, J. C. Lynn, Serena L. Cole, M. G. Williams, Eric P. Seest, Renee M. Zaya, Joel Morris, Chong Kt, Thomas J. Kakuk, R.J Dalga, K D Lovasz, Tomich Pk, M.‐M. Horng, P.L Possert, F.J Schwende
Publikováno v:
Journal of medicinal chemistry. 40(7)
Recently, cyclooctylpyranone derivatives with m-carboxamide substituents (e.g. 2c) were identified as potent, nonpeptidic HIV protease inhibitors, but these compounds lacked significant antiviral activity in cell culture. Substitution of a sulfonamid
Autor:
Roger J. Brideau, Wells Pa, Zhang Jy, Serena L. Cole, Roberts Ed, Thomas J. Kakuk, Kenneth F. Soike, Renee M. Zaya, M.W. Wathen
Publikováno v:
The Journal of infectious diseases. 167(3)
Human respiratory syncytial virus (RSV) is the leading cause of severe bronchiolitis and pneumonia in infants. RSV vaccine development has been stifled for the past 23 years because infants vaccinated with formalin-inactivated (FI) RSV have experienc
Autor:
Thomas J. Kakuk, Michael W. Wathen, Renee M. Zaya, Edward C. Hausknecht, Serena L. Cole, Roger J. Brideau
Publikováno v:
The Journal of infectious diseases. 163(3)
The cotton rat model of human respiratory syncytial virus (RSV) infection was used to study the safety and efficacy of a chimeric FG glycoprotein that was expressed in insect cells using a baculovirus vector. Histologic and virologic examination of v