Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Renee M. McKay"'
Autor:
Chunhui Jiang, Ashwani Kumar, Ze Yu, Tracey Shipman, Yong Wang, Renee M. McKay, Chao Xing, Lu Q. Le
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Neurofibromatosis type 1 (NF1) is one of the most common tumor-predisposing genetic disorders. Neurofibromas are NF1-associated benign tumors. A hallmark feature of neurofibromas is an abundant collagen-rich extracellular matrix (ECM) that constitute
Externí odkaz:
https://doaj.org/article/c58d1cf601994e0eb228352447eddcec
Autor:
Edem Tchegnon, Chung-Ping Liao, Elnaz Ghotbi, Tracey Shipman, Yong Wang, Renee M. McKay, Lu Q. Le
Publikováno v:
JCI Insight, Vol 6, Iss 20 (2021)
Dry eye disease affects over 16 million adults in the US, and the majority of cases are due to Meibomian gland dysfunction. Unfortunately, the identity of the stem cells involved in Meibomian gland development and homeostasis is not well elucidated.
Externí odkaz:
https://doaj.org/article/d956a931a5de4fc7b40d381a8a33922c
Publikováno v:
JID Innovations, Vol 1, Iss 3, Pp 100044- (2021)
Neurofibromatosis type 1 (NF1) is one of the most common neurocutaneous genetic disorders, presenting with different cutaneous features such as café-au-lait macules, intertriginous skin freckling, and neurofibromas. Although most of the disease mani
Externí odkaz:
https://doaj.org/article/1be544bfce7040a89934faf5cdaf43df
Autor:
Joseph Vento, Aditi Mulgaonkar, Layton Woolford, Kien Nham, Alana Christie, Aditya Bagrodia, Alberto Diaz de Leon, Raquibul Hannan, Isaac Bowman, Renee M. McKay, Payal Kapur, Guiyang Hao, Xiankai Sun, James Brugarolas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-6 (2019)
Abstract Background Programmed death-ligand 1 (PD-L1) expression in metastatic renal cell carcinoma (RCC) correlates with a worse prognosis, but whether it also predicts responsiveness to anti-PD-1/PD-L1 therapy remains unclear. Most studies of PD-L1
Externí odkaz:
https://doaj.org/article/8c4fd226b847427c8134b2fba28b7121
Autor:
Qi Cai, Alana Christie, Satwik Rajaram, Qinbo Zhou, Ellen Araj, Suneetha Chintalapati, Nirmish Singla, Jeffrey Cadeddu, Vitaly Margulis, Ivan Pedrosa, Dinesh Rakheja, Renee M. McKay, James Brugarolas, Payal Kapur
Publikováno v:
EBioMedicine, Vol 55, Iss , Pp - (2020)
Externí odkaz:
https://doaj.org/article/76b81fa1c87941a196952613ddd41401
Autor:
Qi Cai, Alana Christie, Satwik Rajaram, Qinbo Zhou, Ellen Araj, Suneetha Chintalapati, Jeffrey Cadeddu, Vitaly Margulis, Ivan Pedrosa, Dinesh Rakheja, Renee M. McKay, James Brugarolas, Payal Kapur
Publikováno v:
EBioMedicine, Vol 51, Iss , Pp - (2020)
Background: Clear cell renal cell carcinoma (ccRCC) is a particularly challenging tumor type because of its extensive phenotypic variability as well as intra-tumoral heterogeneity (ITH). Clinically, this complexity has been reduced to a handful of pa
Externí odkaz:
https://doaj.org/article/2150c4952b1d46199115476db424b46b
Publikováno v:
Cancer Research. 83:5170-5170
Introduction: Neurofibromatosis Type 1 (NF1) is caused by mutations in the NF1 gene that encodes neurofibromin, a RAS GTPase-Activating Protein. Inactivating NF1 mutations result in hyperactivation of RAS-mediated signaling. NF1 patients develop beni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f734602debfa812acd1ba6cc1f1682f
https://doi.org/10.1158/1538-7445.am2023-5170
https://doi.org/10.1158/1538-7445.am2023-5170
Autor:
Oscar Reig Torras, Akhilesh Mishra, Alana Christie, Tiffani McKenzie, Oreoluwa Onabolu, Nirmish Singla, Elizabeth R. Plimack, Cristina Suárez, Moshe C. Ornstein, R. Katherine Alpaugh, Roy Elias, I. Alex Bowman, Renee M. McKay, Christopher Przybycin, Payal Kapur, James Brugarolas, Brian Rini
Publikováno v:
Eur Urol
Active surveillance (AS) may be used in the management of metastatic renal cell carcinoma (mRCC), but consensus regarding its application is lacking. We report an exploratory analysis of prospectively collected data and specimens prespecified in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b14daf40af3336912a7b066038deca
https://europepmc.org/articles/PMC9886196/
https://europepmc.org/articles/PMC9886196/
Publikováno v:
Oncogene
Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disease and one of the most common inherited tumor predisposition syndromes, affecting 1 in 3000 individuals worldwide. The NF1 gene encodes neurofibromin, a large protein with RAS GTP-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3c4d56ae5b996be654f874a0f4474f
https://pubmed.ncbi.nlm.nih.gov/35066574
https://pubmed.ncbi.nlm.nih.gov/35066574
Autor:
Suneetha Chintalapati, Jeffrey A. Cadeddu, Satwik Rajaram, Payal Kapur, Dinesh Rakheja, Vitaly Margulis, Qinbo Zhou, Alana Christie, Renee M. McKay, Qi Cai, James Brugarolas, Nirmish Singla, Ellen Araj, Min Kim, Ivan Pedrosa
Publikováno v:
SSRN Electronic Journal.
Clear cell renal cell carcinoma (ccRCC) exemplifies intratumoral heterogeneity that provides a framework to study tumor evolution. Multiregional genomic sample analyses have shown that tumors evolve from an ancient clone that over time acquires metas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95f4ba62adab7086b04ecde2f05ebb28
https://doi.org/10.2139/ssrn.3424180
https://doi.org/10.2139/ssrn.3424180