Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Renee Leduc"'
Autor:
Irene M. Ghobrial, Edie Weller, Nitin Roper, Renee Leduc, Ranjit Banwait, Meghan Bagshaw, Wanling Xie, Xavier Leleu
Introduction: The serum free light chain (sFLC) has been widely used in the assessment of response in patients with multiple myeloma and other plasma cell dyscrasias. However, its use in Waldenstrom macroglobulinemia (WM) has not been previously asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd1706998d7255f6d57558aaf84b433
https://doi.org/10.1158/1078-0432.c.6518365.v1
https://doi.org/10.1158/1078-0432.c.6518365.v1
Autor:
Irene M. Ghobrial, Edie Weller, Nitin Roper, Renee Leduc, Ranjit Banwait, Meghan Bagshaw, Wanling Xie, Xavier Leleu
Supplementary Table S1 from The Role of Serum Immunoglobulin Free Light Chain in Response and Progression in Waldenstrom Macroglobulinemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08deae28b136ba06657a340f81633816
https://doi.org/10.1158/1078-0432.22441246.v1
https://doi.org/10.1158/1078-0432.22441246.v1
Autor:
Renee Leduc, Kevin O'Regan, Irene M. Ghobrial, Nikhil H. Ramaiya, Edie Weller, Dilek Yarar, Federico Campigotto, Brianna Harris, Xavier Leleu, Meghan Bagshaw, Ranjit Banwait
Publikováno v:
American Journal of Hematology. 86:567-572
Disease assessment in WM is dependent on the quantification of the IgM monoclonal protein and percent involvement of the bone marrow. There is a need for imaging studies that objectively measure tumor load in these patients. In this study, we sought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afe99ac5a0dd2554ad4c3b66d8ee308
https://doi.org/10.1002/ajh.22044
https://doi.org/10.1002/ajh.22044
Autor:
Christopher J. Patterson, Robert Manning, Evdoxia Hatjiharissi, Cao Yang, Jacob D. Soumerai, Zachary R. Hunter, Antonio Sacco, Lian Xu, Bryan Ciccarelli, Allen W. Ho, Andrew R. Branagan, Olivier Tournilhac, Irene M. Ghobrial, Hai T. Ngo, Kelly O’Connor, Xavier Leleu, Steven P. Treon, Aldo M. Roccaro, Sophia Adamia, Daniel Ditzel Santos, Xiaoying Jia, Marybeth Nelson, Renee Leduc, Anne-Sophie Moreau
Publikováno v:
Clinical Lymphoma and Myeloma. 7:S199-S206
Waldenström's macroglobulinemia is a B-cell disorder characterized by bone marrow infiltration with lymphoplasmacytic cells and demonstration of an immunoglobulin M monoclonal gammopathy. Despite advances in therapy, Waldenström's macroglobulinemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42dfdf0622f6d2fded1bc994c9a2b5a4
https://doi.org/10.3816/clm.2007.s.023
https://doi.org/10.3816/clm.2007.s.023
Autor:
Irene M. Ghobrial, Xavier Leleu, Meghan Rourke, Ranjit Banwait, Nitin Roper, Edie Weller, Wanling Xie, Renee Leduc
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 17(9)
Abstract 3095 Introduction: Waldenstrom macroglobulinemia (WM) is a low grade B cell lymphoma characterized by the secretion of IgM protein in the serum. The IgM level lacks sensitivity due to its prolonged half-life. The serum free light chain (sFLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac50164461753f5fa95dadcf2e67cad
https://pubmed.ncbi.nlm.nih.gov/21415221
https://pubmed.ncbi.nlm.nih.gov/21415221
Autor:
Aldo M. Roccaro, Janet Kunsman, Irene M. Ghobrial, Ravi Vij, Jacob P. Laubach, Kenneth C. Anderson, Tiffany Poon, Meghan Bagshaw, Paul G. Richardson, Patricia Maiso, Stacey Chuma, Akari M. Dollard, Scott J. Rodig, Edie Weller, Renee Leduc, Ranjit Banwait, Nikhil C. Munshi, Brianna Harris, Diane Warren, Amy Sam, Robert L. Schlossman, Andrzej Jakubowiak, Philippe Armand
Publikováno v:
The Lancet. Oncology. 12(3)
Summary Background Multiple myeloma is the second most prevalent haematological malignancy and is incurable. Our aim was to assess the response and safety of the combination of temsirolimus (an mTOR inhibitor) and bortezomib in patients with relapsed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1376b03b2f83a5c88d35d3100944757
https://pubmed.ncbi.nlm.nih.gov/21345727
https://pubmed.ncbi.nlm.nih.gov/21345727
Autor:
Steven P. Treon, Renee Leduc, Irene M. Ghobrial, Amy Sam, Swaminathan Padmanabhan, Ashraf Z. Badros, Stacey Chuma, Paul G. Richardson, Meghan Rourke, Janet Kunsman, Brianna Harris, Edie Weller, Tiffany Poon, Jeffrey Matous, Kenneth C. Anderson, Wanling Xie, Diane Warren
Publikováno v:
American journal of hematology. 85(9)
This study aimed to determine the activity and safety of weekly bortezomib and rituximab in patients with untreated Waldenstrom Macroglobulinemia (WM). Patients with no prior therapy and symptomatic disease were eligible. Patients received bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed001e22cdf9ecf68ad48820e19b21a9
https://pubmed.ncbi.nlm.nih.gov/20652865
https://pubmed.ncbi.nlm.nih.gov/20652865
Autor:
Stacey Chuma, Steven P. Treon, Betsy LaPlant, Renee Leduc, Paul G. Richardson, Suzanne R. Hayman, Morie A. Gertz, Leif Bergsagel, Meghan Rourke, Irene M. Ghobrial, Angela Dispenzieri, Stephen M. Ansell, Brianna Harris, Martha Q. Lacy, Thomas E. Witzig, Craig B. Reeder, Kenneth C. Anderson, John K. Camoriano, Daniel J. DeAngelo
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 28(8)
Purpose The phosphatidylinositol 3-kinase/mammalian target of rapamycin (mTOR) signal transduction pathway controls cell proliferation and survival. Everolimus is an oral agent targeting raptor mTOR (mTORC1). The trial's goal was to determine the ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e662e1159841413e7095d95d86c854
https://pubmed.ncbi.nlm.nih.gov/20142598
https://pubmed.ncbi.nlm.nih.gov/20142598
Autor:
Diane Warren, Renee Leduc, Fangxin Hong, Jeffrey Matous, Steven P. Treon, Irene M. Ghobrial, Swaminathan Padmanabhan, Stacey Chuma, Brianna Harris, Meghan Rourke, Kenneth C. Anderson, Janet Kunsman, Paul G. Richardson, Edie Weller, Ashraf Badros, Amy Sam
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 28(8)
Purpose This study aimed to determine activity and safety of weekly bortezomib and rituximab in patients with relapsed/refractory Waldenström macroglobulinemia (WM). Patients and Methods Patients who had at least one previous therapy were eligible.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac472f3d7375013be719d24f29e7104
https://pubmed.ncbi.nlm.nih.gov/20142586
https://pubmed.ncbi.nlm.nih.gov/20142586
Autor:
Renee Leduc, Paul G. Richardson, Feda Azab, Irene M. Ghobrial, Xavier Leleu, Antonio Sacco, Lyuba Varticovski, Stacey Chuma, Nancy Rubin, Brianna Harris, Xiaoying Jia, Meghan Rourke, Kenneth C. Anderson, Fangxin Hong, Abdel Kareem Azab, Peter Sportelli, Scott J. Rodig, Diane Warren, Aldo M. Roccaro, Edie Weller
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 16(3)
Background: Waldenström's macroglobulinemia (WM) is a rare, low-grade lymphoproliferative disorder. Based on preclinical studies, we conducted a phase II clinical trial testing the efficacy and safety of the Akt inhibitor perifosine in patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b025a42c1c984e115a7cbcb9c2deb94
https://pubmed.ncbi.nlm.nih.gov/20103671
https://pubmed.ncbi.nlm.nih.gov/20103671