Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Renee L. Doughman"'
Autor:
Vidhya V. Iyer, Shawn F. Bairstow, Kun Ling, Michael D. Schaller, Deane F. Mosher, Ari J. Firestone, Richard A. Anderson, Renee L. Doughman
Publikováno v:
The Journal of Cell Biology
Engagement of integrin receptors with the extracellular matrix induces the formation of focal adhesions (FAs). Dynamic regulation of FAs is necessary for cells to polarize and migrate. Key interactions between FA scaffolding and signaling proteins ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b06d6301155705ab95f95ad12e5332f
https://doi.org/10.1083/jcb.200310067
https://doi.org/10.1083/jcb.200310067
Publikováno v:
Journal of Membrane Biology. 194:77-89
Phosphatidylinositol 4,5 bisphosphate (PI4,5P(2)) is a critical second messenger that regulates a myriad of diverse cellular activities including modulation of the actin cytoskeleton, vesicle trafficking, focal adhesion formation, and nuclear events.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfa45c2e2d301cc654584190539af09
https://doi.org/10.1007/s00232-003-2027-7
https://doi.org/10.1007/s00232-003-2027-7
Autor:
Matthew W. Bunce, Ari J. Firestone, Richard A. Anderson, Michelle L. Wojtasiak, Renee L. Doughman
Publikováno v:
Journal of Biological Chemistry. 278:23036-23045
Membrane ruffle formation requires remodeling of cortical actin filaments, a process dependent upon the small G-protein Rac. Growth factors stimulate actin remodeling and membrane ruffling by integration of signaling pathways that regulate actin-bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69555a1cde436dab1896ec1c0749a82
https://doi.org/10.1074/jbc.m211397200
https://doi.org/10.1074/jbc.m211397200
Publikováno v:
Nature. 420(6911)
The ability of cells to form cell contacts, adhere to the extracellular matrix, change morphology, and migrate is essential for development, wound healing, metastasis, cell survival and the immune response. These events depend on the binding of integ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3548df511fa6be0bcc4c8fee3d32cc60
https://pubmed.ncbi.nlm.nih.gov/12422220
https://pubmed.ncbi.nlm.nih.gov/12422220