Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Renee K. Johnson"'
Autor:
Charles L. Howe, Renee K. Johnson, Brittany L. Overlee, Jessica A. Sagen, Niyati Mehta, Raquel Farias‐Moeller
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 5, Pp 719-731 (2023)
Abstract Objective Therapeutic strategies for patients with febrile infection‐related epilepsy syndrome (FIRES) are limited, ad hoc, and frequently ineffective. Based on evidence that inflammation drives pathogenesis in FIRES, we used ex vivo stimu
Externí odkaz:
https://doaj.org/article/6957790a93014c7198cf50424774a199
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Same day processing of biospecimens such as blood is not always feasible, which presents a challenge for research programs seeking to study a broad population or to characterize patients with rare diseases. Recruiting sites may not be equipp
Externí odkaz:
https://doaj.org/article/598190a1f3f9485dba6dbf22b218ad14
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-23 (2022)
Abstract The causes of grey matter pathology and diffuse neuron injury in MS remain incompletely understood. Axonal stress signals arising from white matter lesions has been suggested to play a role in initiating this diffuse grey matter pathology. T
Externí odkaz:
https://doaj.org/article/a46d531f7ce247d99dcf9b3fff91ab9a
Autor:
Xu Zhang, Vesselina M. Pearsall, Chase M. Carver, Elizabeth J. Atkinson, Benjamin D. S. Clarkson, Ethan M. Grund, Michelle Baez-Faria, Kevin D. Pavelko, Jennifer M. Kachergus, Thomas A. White, Renee K. Johnson, Courtney S. Malo, Alan M. Gonzalez-Suarez, Katayoun Ayasoufi, Kurt O. Johnson, Zachariah P. Tritz, Cori E. Fain, Roman H. Khadka, Mikolaj Ogrodnik, Diana Jurk, Yi Zhu, Tamara Tchkonia, Alexander Revzin, James L. Kirkland, Aaron J. Johnson, Charles L. Howe, E. Aubrey Thompson, Nathan K. LeBrasseur, Marissa J. Schafer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The authors discovered that proinflammatory senescent myeloid cells may recruit peripheral immune cells in the aged mouse brain. Their findings implicate senescent cell clearance as a strategy to counter aged brain inflammation and cognitive decline.
Externí odkaz:
https://doaj.org/article/563782268a174f9491ef229d9fd5e5e9
Autor:
Parijat Kabiraj, Ethan M. Grund, Benjamin D. S. Clarkson, Renee K. Johnson, Reghann G. LaFrance-Corey, Claudia F. Lucchinetti, Charles L. Howe
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Astrocytes utilize both glycolytic and mitochondrial pathways to power cellular processes that are vital to maintaining normal CNS functions. These cells also mount inflammatory and acute phase reactive programs in response to diverse stimul
Externí odkaz:
https://doaj.org/article/6082d9204e764fd28bf335baa7845997
Autor:
Charles L. Howe, Reghann G. LaFrance-Corey, Brittany L. Overlee, Renee K. Johnson, Benjamin D. S. Clarkson, Emma N. Goddery
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background The pathogenic contribution of neuroinflammation to ictogenesis and epilepsy may provide a therapeutic target for reduction of seizure burden in patients that are currently underserved by traditional anti-seizure medications. The
Externí odkaz:
https://doaj.org/article/36d646d746d34492ad1f55df48b32c7d
Publikováno v:
Journal of Translational Autoimmunity, Vol 5, Iss , Pp 100173- (2022)
Objectives: We sought to develop medium throughput standard operating procedures for screening cryopreserved human peripheral blood mononuclear cells (PBMCs) for CD4+ and CD8+ T cell responses to potential autoantigens. Methods: Dendritic cells were
Externí odkaz:
https://doaj.org/article/893786c919eb4760859f41df43b7fedf
Autor:
Charles L. Howe, Reghann G. LaFrance-Corey, Emma N. Goddery, Renee K. Johnson, Kanish Mirchia
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-14 (2017)
Abstract Background Viral encephalitis is a dangerous compromise between the need to robustly clear pathogen from the brain and the need to protect neurons from bystander injury. Theiler’s murine encephalomyelitis virus (TMEV) infection of C57Bl/6
Externí odkaz:
https://doaj.org/article/3d7fbe9ae8004d078a7263b6bd5668ed
Autor:
Charles L. Howe, Renee K. Johnson, Brittany L. Overlee, Jessica A. Sagen, Niyati Mehta, Raquel Farias‐Moeller
Publikováno v:
Annals of Clinical and Translational Neurology. 10:719-731
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5fddc364b209360fa1cbdceab1bce51
https://doi.org/10.1002/acn3.51755
https://doi.org/10.1002/acn3.51755
Autor:
Niyati P. Mehta, Rachel Sawdy, Kathleen Maloney, Brittany Overlee, Renee K. Johnson, Charles L. Howe, Raquel Farias-Moeller
Publikováno v:
Neurology: Clinical Practice. 13:e200153
ObjectivesFebrile infection–related epilepsy syndrome (FIRES) is characterized by explosive onset refractory status epilepticus (RSE) in healthy individuals that is refractory to antiseizure medication (ASM), continuous anesthetic infusions (CIs),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dbd01d2270b289e31733a93c9fdd669
https://doi.org/10.1212/cpj.0000000000200153
https://doi.org/10.1212/cpj.0000000000200153