Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Renee Fisher"'
Autor:
Amitava Mukherjee, Michael W. Epperly, Renee Fisher, Wen Hou, Donna Shields, M. Saiful Huq, Phillip M. Pifer, Ria Mulherkar, Tyler J. Wilhite, Hong Wang, Peter Wipf, Joel S. Greenberger
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Cellular senescence is involved in the development of pulmonary fibrosis as well as in lung tissue repair and regeneration. Therefore, a strategy of removal of senescent cells by senolytic drugs may not produce the desired therapeutic result
Externí odkaz:
https://doaj.org/article/b26d0e1944c94d44b7aaa72439d312ac
Autor:
Jennifer O. Adeghate, Michael W. Epperly, Katherine Anne Davoli, Kira L. Lathrop, Peter Wipf, Wen Hou, Renee Fisher, Stephanie Thermozier, M. Saiful Huq, Jose-Alain Sahel, Joel S. Greenberger, Andrew W. Eller
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6515 (2024)
We hypothesize that the injection of JP4-039, a mitochondria-targeted nitroxide, prior to irradiation of the mouse retina may decrease apoptosis and reduce neutrophil and macrophage migration into the retina. In our study, we aimed to examine the eff
Externí odkaz:
https://doaj.org/article/14cbaf60514d4b88b678f5b6967c643f
Autor:
Diala F. Hamade, Michael W. Epperly, Renee Fisher, Wen Hou, Donna Shields, Jan-Peter van Pijkeren, Brian J. Leibowitz, Lan G. Coffman, Hong Wang, M. Saiful Huq, Ziyu Huang, Claude J. Rogers, Anda M. Vlad, Joel S. Greenberger, Amitava Mukherjee
Publikováno v:
Cancers, Vol 16, Iss 3, p 474 (2024)
Despite recent advances in cancer therapy, ovarian cancer remains the most lethal gynecological cancer worldwide, making it crucial and of the utmost importance to establish novel therapeutic strategies. Adjuvant radiotherapy has been assessed histor
Externí odkaz:
https://doaj.org/article/f567c6c83dde4f999e7419fd73b9be68
Autor:
Amitava Mukherjee, Michael W. Epperly, Donna Shields, Wen Hou, Renee Fisher, Diala Hamade, Hong Wang, M. Saiful Huq, Riyue Bao, Tracy Tabib, Daisy Monier, Simon Watkins, Michael Calderon, Joel S. Greenberger
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract The role of cellular senescence in radiation-induced pulmonary fibrosis (RIPF) and the underlying mechanisms are unknown. We isolated radiation-induced senescent tdTOMp16 positive mesenchymal stem cells, established their absence of cell div
Externí odkaz:
https://doaj.org/article/0d506b65bfd24c52a6be862101f64fb6
Autor:
Alfredo Rodríguez, Michael Epperly, Jessica Filiatrault, Martha Velázquez, Chunyu Yang, Kelsey McQueen, Larissa A Sambel, Huy Nguyen, Divya Ramalingam Iyer, Ulises Juárez, Cecilia Ayala-Zambrano, David B Martignetti, Sara Frías, Renee Fisher, Kalindi Parmar, Joel S Greenberger, Alan D D'Andrea
Publikováno v:
PLoS Genetics, Vol 18, Iss 11, p e1010459 (2022)
Overexpression of the TGFβ pathway impairs the proliferation of the hematopoietic stem and progenitor cells (HSPCs) pool in Fanconi anemia (FA). TGFβ promotes the expression of NHEJ genes, known to function in a low-fidelity DNA repair pathway, and
Externí odkaz:
https://doaj.org/article/3b6810ea3d60476997167f0422bc2836
Autor:
Diala F. Hamade, Michael W. Epperly, Renee Fisher, Wen Hou, Donna Shields, Jan-Peter van Pijkeren, Amitava Mukherjee, Jian Yu, Brian J. Leibowitz, Anda M. Vlad, Lan Coffman, Hong Wang, M. Saiful Huq, Ziyu Huang, Claude J. Rogers, Joel S. Greenberger
Publikováno v:
Cancers, Vol 15, Iss 6, p 1670 (2023)
Irradiation can be an effective treatment for ovarian cancer, but its use is limited by intestinal toxicity. Thus, strategies to mitigate toxicity are important and can revitalize the current standard of care. We previously established that LR-IL-22
Externí odkaz:
https://doaj.org/article/a74ebfc9d88d45a5be311e90d1ef6636
Autor:
Alexis Espinal, Michael W. Epperly, Amitava Mukherjee, Renee Fisher, Donna Shields, Hong Wang, M. Saiful Huq, Diala Fatima Hamade, Anda M. Vlad, Lan Coffman, Ronald Buckanovich, Jian Yu, Brian J. Leibowitz, Jan-Peter van Pijkeren, Ravi B. Patel, Donna Stolz, Simon Watkins, Asim Ejaz, Joel S. Greenberger
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5616 (2022)
(1) Background: The systemic administration of therapeutic agents to the intestine including cytokines, such as Interleukin-22 (IL-22), is compromised by damage to the microvasculature 24 hrs after total body irradiation (TBI). At that time, there is
Externí odkaz:
https://doaj.org/article/146f8975d3714d18886ab7aac7eccc6f
Publikováno v:
MethodsX, Vol 5, Iss , Pp 337-344 (2018)
In this study, a methodology was evaluated and improved to quickly measure the tensile strength of murine skin in a biomechanical assay for an incisional wound healing model. The aim was to streamline and enhance the wound model, skin specimen prepar
Externí odkaz:
https://doaj.org/article/c9d321b8c7d14779975cb232316fb09b
Autor:
Marla Renee Fisher, Caitlin Turner, Willi McFarland, Aaron Samuel Breslow, Erin C. Wilson, Sean Arayasirikul
Publikováno v:
Transgender Health. 8:200-206
Autor:
Asim Ejaz, J. Peter Rubin, Joel S. Greenberger, Michael W. Epperly, Renee Fisher, Sheeba Shabbir, Jocelyn S. Baker, Benjamin K. Schilling, Katherine S. Yang, Fuat Baris Bengur, Yusuf Surucu
Publikováno v:
Journal of Visualized Experiments.
Radiation-induced skin fibrosis (RISF) can result from a plethora of scenarios including cancer therapy, accidental exposure, or acts of terrorism. Radioactive beams can penetrate through the skin and affect the structures in their path including ski