Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Renee D. Paulsen"'
Autor:
Hyo Jei Claudia Choi, Rachel H. Giles, Renee D. Paulsen, Karlene A. Cimprich, David R. Beier, Danielle K. Manning, Jean-Baptiste Vannier, Andrew C. Kile, Simon J. Boulton, Gisela G. Slaats, Jia-Ren Lin
Publikováno v:
Molecular Cell; Vol 51
Molecular Cell
Molecular Cell
Renal ciliopathies are a leading cause of kidney failure, but their exact etiology is poorly understood. NEK8/NPHP9 is a ciliary kinase associated with two renal ciliopathies in humans and mice, nephronophthisis (NPHP) and polycystic kidney disease.
Autor:
Karlene A. Cimprich, Steven C. Miller, Jayne Hesley, Renee D. Paulsen, Deena V. Soni, Muh-Ching Yee, David E. Solow-Cordero, Tobias Meyer, Roy Wollman, Angela T. Hahn, Anna Guan, Evan F. Cromwell
Publikováno v:
Molecular Cell. 35(2):228-239
Signaling pathways that respond to DNA damage are essential for the maintenance of genome stability and are linked to many diseases, including cancer. Here, a genome-wide siRNA screen was employed to identify additional genes involved in genome stabi
Autor:
Karlene A. Cimprich, Caroline Townsend Stork, Julie Sollier, Renee D. Paulsen, Andrés Aguilera, María L. García-Rubio
Publikováno v:
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
R-loops, consisting of an RNA-DNA hybrid and displaced single-stranded DNA, are physiological structures that regulate various cellular processes occurring on chromatin. Intriguingly, changes in R-loop dynamics have also been associated with DNA dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54bae0d7423a6366d7d8a4d91fe5c89c
https://idus.us.es/handle/11441/67527
https://idus.us.es/handle/11441/67527
Autor:
Karlene A. Cimprich, Renee D. Paulsen
Publikováno v:
DNA repair. 6(7)
The proper detection and repair of DNA damage is essential to the maintenance of genomic stability. The genome is particularly vulnerable during DNA replication, when endogenous and exogenous events can hinder replication fork progression. Stalled re