Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Renee Bullard"'
Autor:
Javier Sánchez-Pozo, Alexander J. Baker-Williams, Mark R. Woodford, Renee Bullard, Beiyang Wei, Mehdi Mollapour, William G. Stetler-Stevenson, Gennady Bratslavsky, Dimitra Bourboulia
Publikováno v:
iScience, Vol 1, Iss , Pp 87-96 (2018)
Summary: The tissue inhibitor of metalloproteinases 2 (TIMP-2) is a specific endogenous inhibitor of matrix metalloproteinase 2 (MMP-2), which is a key enzyme that degrades the extracellular matrix and promotes tumor cell invasion. Although the TIMP-
Externí odkaz:
https://doaj.org/article/162e0a659f004ddc931c533bf3fe8b79
Autor:
Mark R. Woodford, Andrew W. Truman, Diana M. Dunn, Sandra M. Jensen, Richard Cotran, Renee Bullard, Mourad Abouelleil, Kristin Beebe, Donald Wolfgeher, Sara Wierzbicki, Dawn E. Post, Tiffany Caza, Shinji Tsutsumi, Barry Panaretou, Stephen J. Kron, Jane B. Trepel, Steve Landas, Chrisostomos Prodromou, Oleg Shapiro, William G. Stetler-Stevenson, Dimitra Bourboulia, Len Neckers, Gennady Bratslavsky, Mehdi Mollapour
Publikováno v:
Cell Reports, Vol 14, Iss 4, Pp 872-884 (2016)
The molecular chaperone Hsp90 protects deregulated signaling proteins that are vital for tumor growth and survival. Tumors generally display sensitivity and selectivity toward Hsp90 inhibitors; however, the molecular mechanism underlying this phenoty
Externí odkaz:
https://doaj.org/article/94836c555dfb4543879e4bab5562ec97
Autor:
Mehdi Mollapour, Alexander J. Baker-Williams, William G. Stetler-Stevenson, Gennady Bratslavsky, Renee Bullard, Beiyang Wei, Mark R. Woodford, Javier Sánchez-Pozo, Dimitra Bourboulia
Publikováno v:
iScience, Vol 1, Iss, Pp 87-96 (2018)
Summary: The tissue inhibitor of metalloproteinases 2 (TIMP-2) is a specific endogenous inhibitor of matrix metalloproteinase 2 (MMP-2), which is a key enzyme that degrades the extracellular matrix and promotes tumor cell invasion. Although the TIMP-
Autor:
William G. Stetler-Stevenson, Renee Bullard, Mehdi Mollapour, Kristin Beebe, Andrew W. Truman, Tiffany Caza, Len Neckers, Diana M. Dunn, Shinji Tsutsumi, Donald Wolfgeher, Barry Panaretou, Sara Wierzbicki, Chrisostomos Prodromou, Jane B. Trepel, Dimitra Bourboulia, Mark R. Woodford, Dawn E. Post, Gennady Bratslavsky, Stephen J. Kron, Steve K. Landas, Sandra M. Jensen, Richard Cotran, Mourad Abouelleil, Oleg Shapiro
Publikováno v:
Cell reports
Cell Reports, Vol 14, Iss 4, Pp 872-884 (2016)
Woodford, M R, Truman, A W, Dunn, D M, Jensen, S M, Cotran, R, Bullard, R, Abouelleil, M, Beebe, K, Wolfgeher, D, Wierzbicki, S, Post, D E, Caza, T, Tsutsumi, S, Panaretou, B, Kron, S J, Trepel, J B, Landas, S, Prodromou, C, Shapiro, O, Stetler-Stevenson, W G, Bourboulia, D, Neckers, L, Bratslavsky, G & Mollapour, M 2016, ' Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors ', Cell Reports, vol. 14, no. 4, pp. 872-84 . https://doi.org/10.1016/j.celrep.2015.12.084
Cell Reports, Vol 14, Iss 4, Pp 872-884 (2016)
Woodford, M R, Truman, A W, Dunn, D M, Jensen, S M, Cotran, R, Bullard, R, Abouelleil, M, Beebe, K, Wolfgeher, D, Wierzbicki, S, Post, D E, Caza, T, Tsutsumi, S, Panaretou, B, Kron, S J, Trepel, J B, Landas, S, Prodromou, C, Shapiro, O, Stetler-Stevenson, W G, Bourboulia, D, Neckers, L, Bratslavsky, G & Mollapour, M 2016, ' Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors ', Cell Reports, vol. 14, no. 4, pp. 872-84 . https://doi.org/10.1016/j.celrep.2015.12.084
SUMMARY The molecular chaperone Hsp90 protects deregulated signaling proteins that are vital for tumor growth and survival. Tumors generally display sensitivity and selectivity toward Hsp90 inhibitors; however, the molecular mechanism underlying this