Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Renee A. Reijo Pera"'
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra region of the midbrain. Diagnostic criteria for PD require that at least two of three motor s
Externí odkaz:
https://doaj.org/article/1a7afdd518af406bb1c17da48eec0ad6
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, affecting nearly 7–10 million people worldwide. Over the last decade, there has been considerable progress in our understanding of the genetic basis of PD, in the dev
Externí odkaz:
https://doaj.org/article/837bc30862d94cfb8139c026d832ca9d
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Spermatogonial stem cells (SSCs) are a group of adult stem cells in the testis that serve as the foundation of continuous spermatogenesis and male fertility. SSCs are capable of self-renewal to maintain the stability of the stem cell pool and differe
Externí odkaz:
https://doaj.org/article/7880c917f5364272a1dc802dc2366d1e
Autor:
Fang Fang, Ninuo Xia, Benjamin Angulo, Joseph Carey, Zackery Cady, Jens Durruthy-Durruthy, Theo Bennett, Vittorio Sebastiano, Renee A. Reijo Pera
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Self-renewal and pluripotency of human embryonic stem cells (hESCs) depends upon the function of the transcription factor OCT4. Here, the authors identified proteins associated with the OCT4 enhancer, notably ZNF207 that maintains both pluripotency a
Externí odkaz:
https://doaj.org/article/a35e6e487bc6412fa338cd4e9f76670f
Autor:
Fang Fang, Zili Li, Qian Zhao, Zhen Ye, Kai Zhao, Xiuli Gu, Shiliang Shen, Renee A. Reijo Pera, Chengliang Xiong
Publikováno v:
Stem Cell Research, Vol 27, Iss , Pp 136-139 (2018)
Human fibroblasts were isolated from foreskin of a clinically diagnosed 40-year old patient with idiopathic infertility. The fibroblasts were reprogrammed with the Yamanaka KOSM transcriptional factors using the retroviral vectors. The obtained induc
Externí odkaz:
https://doaj.org/article/20e9919f2f0b439b9280b917daef414d
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Reliable assessments of oocyte developmental potential are lacking, making it difficult to select the best quality embryos for transfer after in vitrofertilization. Here, the authors show that a non-invasive measurement of viscoelastic properties pre
Externí odkaz:
https://doaj.org/article/a13e10839eab4bf094edd32bad348922
Autor:
Cyril Ramathal, Jens Durruthy-Durruthy, Meena Sukhwani, Joy E. Arakaki, Paul J. Turek, Kyle E. Orwig, Renee A. Reijo Pera
Publikováno v:
Cell Reports, Vol 7, Iss 4, Pp 1284-1297 (2014)
Historically, spontaneous deletions and insertions have provided means to probe germline developmental genetics in Drosophila, mouse and other species. Here, induced pluripotent stem cell (iPSC) lines were derived from infertile men with deletions th
Externí odkaz:
https://doaj.org/article/d1dbb8e134d6434f8c8989d18808e7cf
Publikováno v:
Human Reproduction Update. 28:313-345
The pathways of gametogenesis encompass elaborate cellular specialization accompanied by precise partitioning of the genome content in order to produce fully matured spermatozoa and oocytes. Transcription factors are an important class of molecules t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cf3f39f22d4fe5b0d7af7194180025
https://doi.org/10.1093/humupd/dmac002
https://doi.org/10.1093/humupd/dmac002
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 1, Pp 36-40 (2020)
Neural Regeneration Research
Neural Regeneration Research
For decades, clinicians have developed medications and therapies to alleviate the symptoms of Parkinson’s disease, but no treatment currently can slow or even stop the progression of this localized neurodegeneration. Fortunately, sparked by the gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983230b72615a2e43bf07aa385db05c6
http://www.nrronline.org/article.asp?issn=1673-5374
http://www.nrronline.org/article.asp?issn=1673-5374
Autor:
Julia Arand, H Rosaria Chiang, David Martin, Michael P Snyder, Julien Sage, Renee A Reijo Pera, Mark Wossidlo
Publikováno v:
EMBO reports. 23(2)
Mammalian development begins in transcriptional silence followed by a period of widespread activation of thousands of genes. DNA methylation reprogramming is integral to embryogenesis and linked to Tet enzymes, but their function in early development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b5da10488c14480fce626bdfdf0a24
https://pubmed.ncbi.nlm.nih.gov/34866320
https://pubmed.ncbi.nlm.nih.gov/34866320