Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rene van der Merwe"'
Autor:
F. Reid, D. Singh, M. Albayaty, R. Moate, E. Jimenez, M.W. Sadiq, D. Howe, I.C. Scott, H. Killick, S. Krishnan, A. Godwood, A. Shukla, L. Hewitt, A. Lei, C. Kell, H. Pandya, null Acknowledgments: Rene van der Merwe, Chase Wang, Neang Ly an
Publikováno v:
B21. BASIC, CLINICAL, AND TRANSLATIONAL COPD STUDIES: THE ONGOING HUNT FOR UNDERLYING MECHANISMS AND THERAPEUTIC TARGETS.
Autor:
Esther Garcia Gil, Jane R. Parnes, Jonathan Corren, Rene van der Merwe, Janet M. Griffiths, Kinga Sałapa, Sean O'Quinn
Publikováno v:
Annals of Allergy, Asthma & Immunology. 126:187-193
Background Patients with severe, uncontrolled asthma experience frequent exacerbations and hospitalization, leading to poor health-related quality of life. In the phase 2b PATHWAY study (NCT02054130), tezepelumab reduced exacerbations by up to 71% an
Autor:
Lorin Roskos, Neang Ly, Yanan Zheng, Jane R. Parnes, Janet M. Griffiths, Rene van der Merwe, Balaji Agoram
Publikováno v:
Journal of clinical pharmacologyReferences. 61(7)
Tezepelumab is a human monoclonal antibody that blocks thymic stromal lymphopoietin, an epithelial cytokine involved in asthma pathogenesis. In the phase 2b PATHWAY study (ClinicalTrials.gov identifier: NCT02054130), tezepelumab significantly reduced
Autor:
Rene van der Merwe, Melinda Gooderham, Stephanie Rippon, Emma Guttman-Yassky, Azra Kurbasic, Sean O'Quinn, Margitta Worm, Nana Kragh, Jonathan I. Silverberg, Andreas Wollenberg
Publikováno v:
Annals of Allergy, Asthma & Immunology. 126:576-583.e4
Background Atopic dermatitis (AD) is associated with a substantial burden on quality of life (QoL). Objective To evaluate the effects of tralokinumab on health-related QoL in patients with moderate-to-severe AD using patient-reported outcomes. Method
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 317:109-115
Metal cations have been shown to depress the floatability of siliceous minerals indicating an interaction with the mineral surface. In this work, the effect of metal cations on the interaction of sodium carboxymethyl cellulose (CMC) depressants and t
Autor:
Peter M. A. Calverley, Sanjay Sethi, Michelle Dawson, Christine K. Ward, Donna K. Finch, Mark Penney, Paul Newbold, René van der Merwe
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background Interleukin-1 receptor 1 (IL-1R1) inhibition is a potential strategy for treating patients with chronic obstructive pulmonary disease (COPD). MEDI8968, a fully human monoclonal antibody, binds selectively to IL-1R1, inhibiting act
Externí odkaz:
https://doaj.org/article/d8fa46126d114930b6eb759ebbd0bc80