Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rene Williams"'
Autor:
Dorota M. Rowczenio, Sónia Melo Gomes, Juan I. Aróstegui, Anna Mensa-Vilaro, Ebun Omoyinmi, Hadija Trojer, Anna Baginska, Alberto Baroja-Mazo, Pablo Pelegrin, Sinisa Savic, Thirusha Lane, Rene Williams, Paul Brogan, Helen J. Lachmann, Philip N. Hawkins
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Cryopyrin-associated periodic syndrome (CAPS) is caused by gain-of-function NLRP3 mutations. Recently, somatic NLRP3 mosaicism has been reported in some CAPS patients who were previously classified as “mutation-negative.” We describe here the cli
Externí odkaz:
https://doaj.org/article/55a8e59f7daa498181d4f19f27b2fc50
Autor:
Ebun Omoyinmi, Helen J. Lachmann, Dorota Rowczenio, Sinisa Savic, H Trojer, Philip N. Hawkins, T. Scambler, Juan I. Aróstegui, Anna Baginska, Julian D. Gillmore, Anna Mensa-Vilaro, Paul A. Brogan, Shelly Pathak, Ashutosh D. Wechalekar, Rene Williams, Roger G. Owen, Taryn Youngstein, Dan Lipsker, Thirusha Lane
Publikováno v:
Blood. 131:974-981
To date, the pathogenic mechanisms underlying Schnitzler syndrome remain obscure, in particular, the interplay between the monoclonal protein and increased interleukin-1β (IL-1β) production, although interest in the contribution of genetic factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26de8764bdfcde724c2141ec259db25a
https://doi.org/10.1182/blood-2017-10-810366
https://doi.org/10.1182/blood-2017-10-810366
Publikováno v:
British journal of nursing (Mark Allen Publishing). 28(18)
Cryopyrin-associated periodic syndrome (CAPS) is a group of rare hereditary autoinflammatory diseases characterised by recurrent flares of mild to severe systemic inflammation and fever. CAPS is the umbrella term for a spectrum of individual conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1f0dd15e18337a38cad1cec218690c
https://pubmed.ncbi.nlm.nih.gov/31597069
https://pubmed.ncbi.nlm.nih.gov/31597069
Autor:
Hal M. Hoffman, Philip N. Hawkins, Ulrich A. Walker, Rene Williams, Jasmin B Kuemmerle-Deschner
Publikováno v:
Arthritis & Rheumatology. 68:516-520
OBJECTIVE: Pneumococcal vaccination is recommended for patients receiving immunosuppressive drugs. We describe unusually severe adverse reactions to pneumococcal vaccination in each of 7 consecutive patients with cryopyrin-associated periodic syndrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7d6157f26a328e697fbf40b9826a2fc
https://doi.org/10.1002/art.39482
https://doi.org/10.1002/art.39482
Autor:
Dorota Rowczenio, Rene Williams, H Trojer, Thirusha Lane, Philip N. Hawkins, Helen J. Lachmann, Taryn Youngstein, Kate David
Publikováno v:
Rheumatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72fa0646b8086e5cf7e04b959ebb95a7
https://doi.org/10.1093/rheumatology/kew176.002
https://doi.org/10.1093/rheumatology/kew176.002
Autor:
Paul A. Brogan, Ruth J. Pepper, Philip N. Hawkins, Taryn Youngstein, H Trojer, Helen J. Lachmann, Thirusha Lane, Rene Williams, Dorota Rowczenio
Publikováno v:
Pediatric Rheumatology Online Journal
Discovery of the role of the IL-1 inflammasome in CAPS has revolutionised treatment, and anti-IL-1 therapies have successfully switched off disease activity in many patients. More than 110 CAPS patients (including 24 children) in the UK have been tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d13813fddfae9c84badbb44090c5cc
https://doi.org/10.1186/1546-0096-13-s1-o65
https://doi.org/10.1186/1546-0096-13-s1-o65
Autor:
Anna Simon, Philip N. Hawkins, C. Michler, John Ryan, Taryn Youngstein, Patrycja Hoffmann, Sean Riminton, H. Ozdogan, Norbert Blank, Len Harty, Helen J. Lachmann, A.P. Headley, Thirusha Lane, Joachim Roesler, Rene Williams, S Urgurlu, Dorota Rowczenio
Publikováno v:
Pediatric Rheumatology Online Journal
Many patients on anti-IL-1 therapy are unable to stop treatment prior to conception or during pregnancy but little data exist regarding safety. We report the outcomes of 20 IL-1 inhibitor exposed pregnancies in 18 women from 7 countries (including th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9c9f354a1aa38e71970dd54bdae3cd
https://doi.org/10.1186/1546-0096-13-s1-o67
https://doi.org/10.1186/1546-0096-13-s1-o67
Autor:
Ulrich A, Walker, Hal M, Hoffman, Rene, Williams, Jasmin, Kuemmerle-Deschner, Philip N, Hawkins
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 68(2)
Pneumococcal vaccination is recommended for patients receiving immunosuppressive drugs. We describe unusually severe adverse reactions to pneumococcal vaccination in each of 7 consecutive patients with cryopyrin-associated periodic syndromes (CAPS).S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::068440b7c8f9ad349a06006e00595acf
https://pubmed.ncbi.nlm.nih.gov/26556233
https://pubmed.ncbi.nlm.nih.gov/26556233
Autor:
Massimo Peruffo, Pablo Contreras-Carballada, Paolo Bertoncello, Rene Williams, Luisa De Cola, Robert Forster, Patrick Unwin
Publikováno v:
ECS Meeting Abstracts. :277-277
not Available.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff2847e5725bb55c622c0dac35484ba3
https://doi.org/10.1149/ma2008-02/2/277
https://doi.org/10.1149/ma2008-02/2/277
Autor:
Gloria Dawson, Vijay V. Kakkar, Rene' Williams, Nancy Ranlall, Douglas Newberry, Shaharam Kashani, Zibgniew Kadziola, Neelam Saba, Mike Scully, Ferruccio De Lorenzo, Ali Noorani
Publikováno v:
American Heart Journal. 143:E3
Background Congestive heart failure (CHF) is associated with a hypercoagulable state. Patients and Methods A single-center, randomized, double-blind, placebo-controlled trial was performed to test the hypothesis that a prophylactic dose of low molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72bbbc099ef9250c64c04a0a4513174
https://doi.org/10.1067/mhj.2002.121268
https://doi.org/10.1067/mhj.2002.121268