Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Rene Quevedo"'
Autor:
Rene Quevedo, Anna Spreafico, Jeff Bruce, Arnavaz Danesh, Samah El Ghamrasni, Amanda Giesler, Youstina Hanna, Cherry Have, Tiantian Li, S. Y. Cindy Yang, Tong Zhang, Sylvia L. Asa, Benjamin Haibe-Kains, Monika Krzyzanowska, Adam C. Smith, Simron Singh, Lillian L. Siu, Trevor J. Pugh
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-15 (2020)
Abstract Background Pancreatic neuroendocrine tumors (PANETs) are rare, slow growing cancers that often present with local and distant metastasis upon detection. PANETS contain distinct karyotypes, epigenetic dysregulation, and recurrent mutations in
Externí odkaz:
https://doaj.org/article/b288eabe753d44ec8ac66768485572df
Autor:
S. Y. Cindy Yang, Stephanie Lheureux, Katherine Karakasis, Julia V. Burnier, Jeffery P. Bruce, Derek L. Clouthier, Arnavaz Danesh, Rene Quevedo, Mark Dowar, Youstina Hanna, Tiantian Li, Lin Lu, Wei Xu, Blaise A. Clarke, Pamela S. Ohashi, Patricia A. Shaw, Trevor J. Pugh, Amit M. Oza
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-17 (2018)
Abstract Background Patients diagnosed with high-grade serous ovarian cancer (HGSOC) who received initial debulking surgery followed by platinum-based chemotherapy can experience highly variable clinical responses. A small percentage of women experie
Externí odkaz:
https://doaj.org/article/442a3e5a464143828f9cb795c9072289
Autor:
Zhaleh Safikhani, Petr Smirnov, Kelsie L. Thu, Jennifer Silvester, Nehme El-Hachem, Rene Quevedo, Mathieu Lupien, Tak W. Mak, David Cescon, Benjamin Haibe-Kains
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Altered mRNA splicing features in many cancers, but it has not been linked to drug response. Here, with their meta-analytic framework, the authors analyse pharmacogenomic data to identify isoform-based biomarkers predictive of in vitro drug response,
Externí odkaz:
https://doaj.org/article/cf7eac9f211140b5ac75f6d34ebece89
Autor:
Zhaleh Safikhani, Nehme El-Hachem, Rene Quevedo, Petr Smirnov, Anna Goldenberg, Nicolai Juul Birkbak, Christopher Mason, Christos Hatzis, Leming Shi, Hugo JWL Aerts, John Quackenbush, Benjamin Haibe-Kains
Publikováno v:
F1000Research, Vol 5 (2016)
In 2013 we published an analysis demonstrating that drug response data and gene-drug associations reported in two independent large-scale pharmacogenomic screens, Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Cell Line Encyclopedia (CCLE),
Externí odkaz:
https://doaj.org/article/4ff889a58ef74aa58f2a2faddabae771
Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro
Autor:
Zhaleh Safikhani, Petr Smirnov, Kelsie L. Thu, Jennifer Silvester, Nehme El-Hachem, Rene Quevedo, Mathieu Lupien, Tak W. Mak, David Cescon, Benjamin Haibe-Kains
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
In the original version of this Article, financial support was not fully acknowledged. This error has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/9191ce76cbef48729acb0b446760ba48
Autor:
Trevor J. Pugh, Mathieu Lupien, Susan J. Done, Dave W. Cescon, Jüri Reimand, Paul Guilhamon, S.Y. Cindy Yang, Leslie E. Oldfield, Jeff P. Bruce, Helen Zhu, Iulia Cirlan, Youstina Hanna, Parisa Mazrooei, James Hawley, Rene Quevedo, Samah El Ghamrasni
Whole-genome sequencing of primary breast tumors enabled the identification of cancer driver genes and noncoding cancer driver plexuses from somatic mutations. However, differentiating driver from passenger events among noncoding genetic variants rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a976ceefb6fe1848c7e09f0e6661a1a
https://doi.org/10.1158/1541-7786.c.6545226.v1
https://doi.org/10.1158/1541-7786.c.6545226.v1
Autor:
Trevor J. Pugh, Mathieu Lupien, Susan J. Done, Dave W. Cescon, Jüri Reimand, Paul Guilhamon, S.Y. Cindy Yang, Leslie E. Oldfield, Jeff P. Bruce, Helen Zhu, Iulia Cirlan, Youstina Hanna, Parisa Mazrooei, James Hawley, Rene Quevedo, Samah El Ghamrasni
Supplementary Figure from Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002d1a40bf6c1777c932897b393e09e5
https://doi.org/10.1158/1541-7786.22526841.v1
https://doi.org/10.1158/1541-7786.22526841.v1
Autor:
Trevor J. Pugh, Mathieu Lupien, Susan J. Done, Dave W. Cescon, Jüri Reimand, Paul Guilhamon, S.Y. Cindy Yang, Leslie E. Oldfield, Jeff P. Bruce, Helen Zhu, Iulia Cirlan, Youstina Hanna, Parisa Mazrooei, James Hawley, Rene Quevedo, Samah El Ghamrasni
Supplementary Table from Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129f0224300ad2d003e63521ab862238
https://doi.org/10.1158/1541-7786.22526838
https://doi.org/10.1158/1541-7786.22526838
Autor:
Leslie E. Oldfield, Jeff Bruce, Trevor J. Pugh, Mathieu Lupien, James R. Hawley, Rene Quevedo, Parisa Mazrooei, Samah El Ghamrasni, Iulia Cirlan, Jüri Reimand, Helen Zhu, S. Y. Cindy Yang, Susan J. Done, Youstina Hanna, Paul Guilhamon, Cescon D
Publikováno v:
Molecular Cancer Research. 20:102-113
Whole-genome sequencing of primary breast tumors enabled the identification of cancer driver genes and noncoding cancer driver plexuses from somatic mutations. However, differentiating driver from passenger events among noncoding genetic variants rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bb73934181d57a9b6233e797d67be0c
https://doi.org/10.1158/1541-7786.mcr-21-0471
https://doi.org/10.1158/1541-7786.mcr-21-0471
Autor:
Melyssa Aronson, Leslie Oldfield, Spring Holter, Tiantian Li, Aaron Pollett, Alicia A. Tone, Melissa Edwards, Sarah E. Ferguson, Rene Quevedo, Blaise A. Clarke, Uri Tabori, Trevor J. Pugh, Jordan Lerner-Ellis, Emily Van de Laar, Steven Gallinger
Publikováno v:
The Journal of Molecular Diagnostics. 23:242-252
Clinical testing for mismatch repair (MMR) deficiency often entails serial testing of tumor and constitutional DNA using multiple assays. To minimize cost and specimen requirements of MMR testing, we developed an integrated targeted sequencing protoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1314af9508d45fef9f507266b34412ad
https://doi.org/10.1016/j.jmoldx.2020.11.006
https://doi.org/10.1016/j.jmoldx.2020.11.006