Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rene J. Trabanino"'
Publikováno v:
Biochemistry. 40:15471-15482
Magnetic dipolar interactions between pairs of solvent-exposed nitroxide side chains separated by approximately one to four turns along an alpha-helix in T4 lysozyme are investigated. The interactions are analyzed both in frozen solution (rigid latti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efbb677a9dd6783597ff3b6790c6ee88
https://doi.org/10.1021/bi011544w
https://doi.org/10.1021/bi011544w
We examine here the role of the red, green, and blue human opsin structures in modulating the absorption properties of 11-cis-retinal bonded to the protein via a protonated Schiff base (PSB). We built the three-dimensional structures of the human red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69cf0f88de42399feb7112919e24303
https://resolver.caltech.edu/CaltechAUTHORS:20170609-074403703
https://resolver.caltech.edu/CaltechAUTHORS:20170609-074403703
Autor:
Richard Horuk, Wely B. Floriano, Sunil Koovakat, Sabine Schlyer, Nagarajan Vaidehi, Laura Dunning, James M. Fox, Ravinder Abrol, Filipa Lopes de Mendonça, James E. Pease, Rene J. Trabanino, Monica Kochanny, Meina Liang, William A. Goddard, Shantanu Sharma
Publikováno v:
The Journal of biological chemistry. 281(37)
A major challenge in the application of structure-based drug design methods to proteins belonging to the superfamily of G protein-coupled receptors (GPCRs) is the paucity of structural information (1). The 19 chemokine receptors, belonging to the Cla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af53fcebb2f9c3de7d4ee6314190994b
https://pubmed.ncbi.nlm.nih.gov/16837468
https://pubmed.ncbi.nlm.nih.gov/16837468
Autor:
Victor Wai Tak Kam, Wely B. Floriano, Nagarajan Vaidehi, Spencer E. Hall, Rene J. Trabanino, William A. Goddard
G-protein-coupled receptors (GPCRs) are involved in cell communication processes and with mediating such senses as vision, smell, taste, and pain. They constitute a prominent superfamily of drug targets, but an atomic-level structure is available for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44829307959b1748f9fd1bbbe34f6d5f
https://resolver.caltech.edu/CaltechAUTHORS:20190301-092706690
https://resolver.caltech.edu/CaltechAUTHORS:20190301-092706690
Autor:
Victor Wai Tak Kam, Spencer E. Hall, Peter L. Freddolino, Rene J. Trabanino, William A. Goddard, M. Yashar S. Kalani, Nagarajan Vaidehi, Wely B. Floriano, Maziyar A. Kalani
Dopamine neurotransmitter and its receptors play a critical role in the cell signaling process responsible for information transfer in neurons functioning in the nervous system. Development of improved therapeutics for such disorders as Parkinson's d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18d59269502caa063825d1035db255a
https://resolver.caltech.edu/CaltechAUTHORS:KALpnas04
https://resolver.caltech.edu/CaltechAUTHORS:KALpnas04
Autor:
Victor Wai Tak Kam, Spencer E. Hall, Nagarajan Vaidehi, Wely B. Floriano, William A. Goddard, Peter L. Freddolino, Rene J. Trabanino, M. Yashar S. Kalani
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 101(9)
We report the 3D structure of human β2 adrenergic receptor (AR) predicted by using the MembStruk first principles method. To validate this structure, we use the HierDock first principles method to predict the ligand-binding sites for epinephrine and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2314ed257611ef7b627ce5beb3b2f7ce
https://pubmed.ncbi.nlm.nih.gov/14981238
https://pubmed.ncbi.nlm.nih.gov/14981238
Autor:
Peter L. Freddolino, Nagarajan Vaidehi, Rene J. Trabanino, Wely B. Floriano, William A. Goddard, Eun Jung Choi, Georgios Zamanakos, Spencer E. Hall
G protein-coupled receptors (GPCRs) mediate our sense of vision, smell, taste, and pain. They are also involved in cell recognition and communication processes, and hence have emerged as a prominent superfamily for drug targets. Unfortunately, the at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f02f8cea7d96c31b637967d826b350
https://resolver.caltech.edu/CaltechAUTHORS:20141120-095059378
https://resolver.caltech.edu/CaltechAUTHORS:20141120-095059378
Publikováno v:
Journal of Physical Chemistry B; Aug2006, Vol. 110 Issue 34, p17230-17239, 10p