Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rene D. Miranda"'
Autor:
Zhong Sheng Ji, Maureen E. Balestra, Michael A. Pleiss, Dah Eun Jeong, Anke Meyer-Franke, Qin Xu, David W. Walker, Zhaoping Liu, Karl H. Weisgraber, Yadong Huang, John C. Voss, Stephen B. Freedman, Jens Brodbeck, Rene D. Miranda, Hung Kai Chen, James G. McGuire, Madhu S. Budamagunta, Robert W. Mahley
Publikováno v:
Journal of Biological Chemistry. 287:5253-5266
Apolipoprotein E4 (apoE4), the major genetic risk factor for late onset Alzheimer disease, assumes a pathological conformation, intramolecular domain interaction. ApoE4 domain interaction mediates the detrimental effects of apoE4, including decreased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a7cef155e044df87d4f19e336db86d
https://doi.org/10.1074/jbc.m111.276162
https://doi.org/10.1074/jbc.m111.276162
Autor:
M. Mahmood Hussain, Walter J. Brecht, Robert W. Mahley, Zhong-Sheng Ji, Thomas L. Innerarity, Rene D. Miranda
Publikováno v:
Journal of Biological Chemistry. 268:10160-10167
Addition of apolipoprotein (apo) E to rabbit beta-very low density lipoproteins (beta-VLDL) has been shown to result in a marked enhancement of their binding and uptake by various cell types. Apolipoprotein E binds to lipoprotein receptors and proteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d72c331128f4f37da44495172fdee39
https://doi.org/10.1016/s0021-9258(18)82186-x
https://doi.org/10.1016/s0021-9258(18)82186-x
Autor:
Rene D. Miranda, Stephen B. Freedman, Robert W. Mahley, Sara E. Dodson, Yadong Huang, Karl H. Weisgraber, Hung-Kai Chen, Ian J. Reynolds, Zhong-Sheng Ji, Charles Rosenblum
Apolipoprotein (apo) E4 is the major genetic risk factor for late-onset Alzheimer disease (AD). ApoE4 assumes a pathological conformation through an intramolecular interaction mediated by Arg-61 in the amino-terminal domain and Glu-255 in the carboxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abaa6177cb0d71ed5b8e37253a180b37
https://europepmc.org/articles/PMC3037634/
https://europepmc.org/articles/PMC3037634/
