Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rene Baerentsen"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Neisseria meningitidis and Neisseria gonorrhoeae are two obligate human pathogens that have evolved to be uniquely adapted to their host. The meningococcus is frequently carried asymptomatically in the nasopharynx, while gonococcal infection of the u
Externí odkaz:
https://doaj.org/article/bc051f35d43341d4acbd2c7109ef12c0
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Bacterial multidrug tolerance and persistence are problems of increasing scientific and medical significance. The first gene discovered to confer persistence was hipAhipBAE. coli
Externí odkaz:
https://doaj.org/article/ce4ca8757bde457d8dc8253ac4d9f73a
Autor:
Stine Vang Nielsen, Kathryn Jane Turnbull, Mohammad Roghanian, Rene Bærentsen, Maja Semanjski, Ditlev E. Brodersen, Boris Macek, Kenn Gerdes
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Type II toxin-antitoxin (TA) modules encode a stable toxin that inhibits cell growth and an unstable protein antitoxin that neutralizes the toxin by direct protein-protein contact. hipBA of Escherichia coli strain K-12 codes for HipA, a seri
Externí odkaz:
https://doaj.org/article/7a936f4f05fe4d779f30afaf9f227b84
Publikováno v:
Gerdes, K, Bærentsen, R & Brodersen, D E 2021, ' Phylogeny Reveals Novel HipA-Homologous Kinase Families and Toxin-Antitoxin Gene Organizations ', mBio, vol. 12, no. 3, pp. e0105821 . https://doi.org/10.1128/mBio.01058-21
mBio
mBio, Vol 12, Iss 3 (2021)
Gerdes, K, Bærentsen, R & Brodersen, D E 2021, ' Phylogeny Reveals Novel HipA-Homologous Kinase Families and Toxin-Antitoxin Gene Organizations ', mBio, vol. 12, no. 3, e01058-21 . https://doi.org/10.1128/mBio.01058-21
mBio
mBio, Vol 12, Iss 3 (2021)
Gerdes, K, Bærentsen, R & Brodersen, D E 2021, ' Phylogeny Reveals Novel HipA-Homologous Kinase Families and Toxin-Antitoxin Gene Organizations ', mBio, vol. 12, no. 3, e01058-21 . https://doi.org/10.1128/mBio.01058-21
Toxin-antitoxin modules function in the genetic stability of mobile genetic elements, bacteriophage defense, and antibiotic tolerance. A gain-of-function mutation of the Escherichia coli K-12 hipBA module can induce antibiotic tolerance in a subpopul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5687fc1df46f25998885a30911177ffd
https://pure.au.dk/portal/da/publications/phylogeny-reveals-novel-hipahomologous-kinase-families-and-toxinantitoxin-gene-organizations(95bdf0e0-7213-4cfe-90fe-b27f89fde001).html
https://pure.au.dk/portal/da/publications/phylogeny-reveals-novel-hipahomologous-kinase-families-and-toxinantitoxin-gene-organizations(95bdf0e0-7213-4cfe-90fe-b27f89fde001).html
Publikováno v:
Bærentsen, R L, Brodersen, D E & Zhang, Y E 2019, ' Evolution of the bacterial nucleosidase PpnN and its relation to the stringent response ', Microbial Cell, vol. 6, no. 9, pp. 450-453 . https://doi.org/10.15698/mic2019.09.692
Bærentsen, R L, Brodersen, D E & Zhang, Y E 2019, ' Evolution of the bacterial nucleosidase PpnN and its relation to the stringent response ', Microbial Cell Factories, vol. 6, no. 9, pp. 450-453 . https://doi.org/10.15698/mic2019.09.692
Microbial Cell, Vol 6, Iss 9, Pp 450-453 (2019)
Bærentsen, R L, Brodersen, D E & Zhang, Y E 2019, ' Evolution of the bacterial nucleosidase PpnN and its relation to the stringent response ', Microbial Cell Factories, vol. 6, no. 9, pp. 450-453 . https://doi.org/10.15698/mic2019.09.692
Microbial Cell, Vol 6, Iss 9, Pp 450-453 (2019)
In our recent publication (Zhang et al., 2019), we demonstrate an interesting mode of regulation of purine metabolism unique to Proteobacteria. In this microreview, we would like to reflect on the ideas put forward, with special focus on protein doma
Autor:
Stine Vang Nielsen, Taoran Li, Ditlev E. Brodersen, Jan Skov Pedersen, Jeppe Lyngsø, Rene Baerentsen, Michael Sørensen, Helena Ø. Rasmussen, Kenn Gerdes
Publikováno v:
The FASEB Journal. 35
Toxin – Antitoxin modules function in the genetic stability of mobile genetic elements, bacteriophage defense, and antibiotic tolerance. A gain-of-function mutation of the Escherichia coli K-12 hipBA module can induce antibiotic tolerance in a subp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f85c4007cca40635b0f92fe87e3b404
https://doi.org/10.1101/2021.04.14.439929
https://doi.org/10.1101/2021.04.14.439929
Autor:
Maja Semanjski, Boris Macek, Kathryn Jane Turnbull, Mohammad Roghanian, Rene Baerentsen, Ditlev E. Brodersen, Stine Vang Nielsen, Kenn Gerdes
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
Nielsen, S V, Turnbull, K J, Roghanian, M, Bærentsen, R, Brodersen, D E, Semanjski, M, Macek, B & Gerdes, K 2019, ' Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase ' mBio (Online) .
Nielsen, S V, Turnbull, K J, Roghanian, M, Bærentsen, R, Semanjski, M, Brodersen, D E, Macek, B & Gerdes, K 2019, ' Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase ', mBio, vol. 10, no. 3, e-01138-19 . https://doi.org/10.1128/mBio.01138-19
mBio
Vang Nielsen, S, Turnbull, K J, Roghanian, M, Bærentsen, R, Semanjski, M, Brodersen, D E, Macek, B & Gerdes, K 2019, ' Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase ', mBio, vol. 10, no. 3, e01138-19 . https://doi.org/10.1128/mBio.01138-19
mBio, Vol 10, Iss 3, p e01138-19 (2019)
Nielsen, S V, Turnbull, K J, Roghanian, M, Bærentsen, R, Brodersen, D E, Semanjski, M, Macek, B & Gerdes, K 2019, ' Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase ' mBio (Online) .
Nielsen, S V, Turnbull, K J, Roghanian, M, Bærentsen, R, Semanjski, M, Brodersen, D E, Macek, B & Gerdes, K 2019, ' Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase ', mBio, vol. 10, no. 3, e-01138-19 . https://doi.org/10.1128/mBio.01138-19
mBio
Vang Nielsen, S, Turnbull, K J, Roghanian, M, Bærentsen, R, Semanjski, M, Brodersen, D E, Macek, B & Gerdes, K 2019, ' Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase ', mBio, vol. 10, no. 3, e01138-19 . https://doi.org/10.1128/mBio.01138-19
mBio, Vol 10, Iss 3, p e01138-19 (2019)
Bacterial toxin-antitoxin (TA) modules confer multidrug tolerance (persistence) that may contribute to the recalcitrance of chronic and recurrent infections. The first high-persister gene identified was hipA of Escherichia coli strain K-12, which enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537bf68cb2201c56aa130d75fff927bc
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167019
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167019
Autor:
Tobias Fuhrer, Uwe Sauer, Ditlev E. Brodersen, Yong Everett Zhang, Kenn Gerdes, Rene Baerentsen
Publikováno v:
Molecular cell 74(6), 1239-1249.e4 (2019). doi:10.1016/j.molcel.2019.03.035
Zhang, Y, Bærentsen, R L, Fuhrer, T, Sauer, U, Gerdes, K & Brodersen, D E 2019, ' (p)ppGpp Regulates a bacterial nucleosidase by an allosteric two-domain switch ', Molecular Cell, vol. 74, no. 6, pp. 1239-1249.e4 . https://doi.org/10.1016/j.molcel.2019.03.035
Microbial Cell
Zhang, Y, Bærentsen, R L, Fuhrer, T, Sauer, U, Gerdes, K & Brodersen, D E 2019, ' (p)ppGpp Regulates a bacterial nucleosidase by an allosteric two-domain switch ', Molecular Cell, vol. 74, no. 6, pp. 1239-1249.e4 . https://doi.org/10.1016/j.molcel.2019.03.035
Microbial Cell
In our recent publication (Zhang et al., 2019), we demonstrate an interesting mode of regulation of purine metabolism unique to Proteobacteria. In this microreview, we would like to reflect on the ideas put forward, with special focus on protein doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1242dff43ba85527ef719101d8026aff
https://bib-pubdb1.desy.de/record/425966
https://bib-pubdb1.desy.de/record/425966
Publikováno v:
Frontiers in Cellular & Infection Microbiology; 6/24/2022, Vol. 12, p1-13, 13p