Ivermectin induces mitophagy in H9c2 cells via activation of the PINK1/Parkin pathway

Autor: Yanmin Jia, Rene Wang, Baoxue Han

Publikováno v: Food Science and Technology, Volume: 42, Article number: e65621, Published: 22 OCT 2021
Food Science and Technology (2021)
Food Science and Technology v.42 2022
Food Science and Technology (Campinas)
Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA)
instacron:SBCTA
Food Science and Technology, Issue: ahead, Published: 22 OCT 2021

Ivermectin (IVM), a remarkable broad-spectrum anthelmintic and insecticides, which also contributes to clinical application. However, IVM induction of cytotoxicity through mitophagy has not been consistently proven in vitro. Here we investigate the c

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