Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Rendong Yang"'
Autor:
Yangyang Li, Rendong Yang
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background With the surge in genomic data driven by advancements in sequencing technologies, the demand for efficient bioinformatics tools for sequence analysis has become paramount. BLAST-like alignment tool (BLAT), a sequence alignment too
Externí odkaz:
https://doaj.org/article/0c1ef74c41884e20b5c879caa01562b0
Autor:
Meixia Che, Aashi Chaturvedi, Sarah A. Munro, Samuel P. Pitzen, Alex Ling, Weijie Zhang, Josh Mentzer, Sheng-Yu Ku, Loredana Puca, Yanyun Zhu, Andries M. Bergman, Tesa M. Severson, Colleen Forster, Yuzhen Liu, Jacob Hildebrand, Mark Daniel, Ting-You Wang, Luke A. Selth, Theresa Hickey, Amina Zoubeidi, Martin Gleave, Rohan Bareja, Andrea Sboner, Wayne Tilley, Jason S. Carroll, Winston Tan, Manish Kohli, Rendong Yang, Andrew C. Hsieh, Paari Murugan, Wilbert Zwart, Himisha Beltran, R. Stephanie Huang, Scott M. Dehm
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
While many treatments for prostate cancer suppress the androgen receptor it becomes reactivated during disease progression. Here, the authors show that a KLF5 transcriptional programme is also activated during treatment and promotes migration and the
Externí odkaz:
https://doaj.org/article/0d96a02002f9414c84ce1f8008d43a91
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-6 (2021)
Abstract Background Long non-coding RNAs (lncRNAs) are a growing focus in cancer research. Deciphering pathways influenced by lncRNAs is important to understand their role in cancer. Although knock-down or overexpression of lncRNAs followed by gene e
Externí odkaz:
https://doaj.org/article/399fa76ceb554c6caf136122f79790c7
Autor:
Abdallah M. Eteleeb, David A. Quigley, Shuang G. Zhao, Duy Pham, Rendong Yang, Scott M. Dehm, Jingqin Luo, Felix Y. Feng, Ha X. Dang, Christopher A. Maher
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Whole genome sequencing (WGS) has enabled the discovery of genomic structural variants (SVs), including those targeting intergenic and intronic non-coding regions that eluded previous exome focused strategies. However, the field currently la
Externí odkaz:
https://doaj.org/article/028d671856044b26a0873e62b77eaea6
Autor:
Yunru Chen, Qing Li, Kangsheng Tu, Yuanguo Wang, Xianghu Wang, Dandan Liu, Chen Chen, Donglian Liu, Rendong Yang, Wei Qiu, Ningling Kang
Publikováno v:
Hepatology Communications, Vol 4, Iss 2, Pp 268-283 (2020)
Transforming growth factor β (TGFβ) induces hepatic stellate cell (HSC) differentiation into tumor‐promoting myofibroblast, although underlying mechanism remains incompletely understood. Focal adhesion kinase (FAK) is activated in response to TGF
Externí odkaz:
https://doaj.org/article/4b2ff0b475dc43c89354adb495d64b87
Autor:
Ting-You Wang, Rendong Yang
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100788- (2021)
Summary: Exitron splicing (EIS) events in cancers can disrupt functional protein domains to cause cancer driver effects. EIS has been recognized as a new source of tumor neoantigens. Here, we describe an integrated protocol for EIS and EIS-derived ne
Externí odkaz:
https://doaj.org/article/802bfb9916044af2967df5ef7b8fffb0
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Insertions and deletions (indels) are a major class of genomic variation associated with human disease. Indels are primarily detected from DNA sequencing (DNA-seq) data but their transcriptional consequences remain unexplored due
Externí odkaz:
https://doaj.org/article/93f949c1084a47bf83a3147bd45bd9dc
Autor:
Christine Henzler, Yingming Li, Rendong Yang, Terri McBride, Yeung Ho, Cynthia Sprenger, Gang Liu, Ilsa Coleman, Bryce Lakely, Rui Li, Shihong Ma, Sean R. Landman, Vipin Kumar, Tae Hyun Hwang, Ganesh V. Raj, Celestia S. Higano, Colm Morrissey, Peter S. Nelson, Stephen R. Plymate, Scott M. Dehm
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Castration-resistant prostate cancer frequently presents with persistent androgen receptor signalling. Here, the authors find that the androgen receptor is subject to genetic rearrangements, resulting in variants with ligand-independent activity.
Externí odkaz:
https://doaj.org/article/881742f5c87d4d33a058d2ab18e6588c
Autor:
Rendong Yang, Li Chen, Scott Newman, Khanjan Gandhi, Gregory Doho, Carlos S. Moreno, Paula M. Vertino, Leon Bernal-Mizarchi, Sagar Lonial, Lawrence H. Boise, Michael Rossi, Jeanne Kowalski, Zhaohui S. Qin
Publikováno v:
Cancer Informatics, Vol 2014, Iss Suppl. 2, Pp 49-53 (2014)
Externí odkaz:
https://doaj.org/article/cdabd65336a14370982d6647b782b316
Autor:
Qiqi Wang, Wei Zhang, Rendong Yang, Yuanxiu Huang, Lin Zhang, Peishan Ning, Xunjie Cheng, David C Schwebel, Guoqing Hu, Hongyan Yao
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137954 (2015)
To report common traffic violations in bus drivers and the factors that influence those violations in urban China.We conducted an observational study to record three types of traffic violations among bus drivers in Changsha City, China: illegal stopp
Externí odkaz:
https://doaj.org/article/4986f8392092433b95e74e578c709211