Etrolizumab for maintenance therapy in patients with moderately to severely active ulcerative colitis (LAUREL): a randomised, placebo-controlled, double-blind, phase 3 study

Autor: Abraham, Philip, Acir Crippa Júnior, Mauro, Aguilar, Humberto, Ahmed, Tasneem, Altorjay, Istvan, Andersen, Vibeke, Arai, Ronen, Arnold, Hays, Ausk, Karlee, Axler, Jeffrey, Ayub, Kamran, Balekuduru, Avinash, Barbalaco Neto, Guerino, Bassan, Isaac, Behm, Brian, Bekal, Pradeep, Bhatia, Shobna, Bod, Barnabas, Brandão Mello, Carlos Eduardo, Brandeburova, Julia, Breedt, Johannes, Bressler, Brian, Chopey, Ivan, Connor, Michael, Corlin, Richard, Cortez Hernandez, Carlos Alejandro, De, Arijit, de Sá Rolim, Alexander, Di Felice Boratto, Sandra, Dixon, Tyler, Dourado Poli, Debora, Dresner, David, Du Vall, George Aaron, Ebert, Matthias, Ehehalt, Robert, Ertan, Atilla, Escarcega Valencia, Ruben, Etzel, Jason, Fallingborg, Jan, Feagan, Brian, Fedurco, Miroslav, Fernandez Castro, Enrique, Ferreira de Almeida Borges, Valéria, Finklestein, Mark, Fischer, Andreas, Fleisher, Mark, Flores Rendon, Angel Ricardo, Fogel, Ronald, Franceschi Junior, Osvaldo, Freedland, Curtis, Gatof, David, Gill, Kanwar, Glerup, Henning, Gokak, Vardaraj, Goldin, Eran, Gomez Jaramillo, Hector Alejandro, Gupta, Nitin, Gurzo, Zoltan, Gyrina, Olga, Habeeb, Mohammed Aejaz, Hanauer, Stephen, Hardi, Robert, Harlan, William, Hemaidan, Ammar, Heyman, Melvin, Hoffmann, Peter, Holderman, William, Holtkamp-Endemann, Frank, Horvat, Gyula, Isaacs, Kim, Israeli, Eran, Jankiel Miszputen, Sender, Jensen, Søren, Johnson, Kenneth, Jones, Jennifer, Junior, Osvaldo, Kadleckova, Barbora, Kalla, Mukesh, Kallo, Zsuzsanna, Karyotakis, Nicholas, Katz, Lior, Katz, Leo, Kaur, Nirmal, Khanna, Reena, Kohout, Pavel, Lakatos, Peter, Larriva de los Reyes, Emmanuel, Lee, Robert, Leman, Bernard, Levchenko, Olena, Levine, Henry, Libanez Bessa Campelo Braga, Lúcia, Loftus, Edward, Lohdanidi, Tetiana, Longman, Randy, Lozano, Josefina, Maaser, Christian, Madi-Szabo, Laszlo, Malluta, Everson Fernando, Marshall, John, Martinez Silva, Francisca, Maynard, Kenneth, Meder, Agnieszka, Mehta, Chetan, Minarik, Peter, Mueller, Joachim, Mukewar, Shrikant, Nagy, Bela, Neiko, Vasyl, Neurath, Markus, Nichol, Brian, Novick, James, Pai, Nitin, Pandak, William, Panigrahi, Sarat, Pape, Ulrich-Frank, Paraná, Raymundo, Parekh, Nimisha, Patel, Bhaktasharan, Pecsi, Gyula, Peralta, Sergio, Pesta, Martin, Peterfai, Eva, Petruzzellis, Carlo, Petryka, Robert, Pica, Roberta, Piniella, Carlos, Pratha, Vijayalakshmi, Prochazka, Vlastimil, Prokopchuk, Sergey, Prystupa, Ludmyla, Puri, Amarender, Rainis, Tova, Ramesh Kumar, Bhashyakarla, Ramos Júnior, Odery, Rishko, Iaroslava, Ritter, Timothy, Robbins, Bryan, Rock, Elizabeth, Rodrigues Borba, Marcelo, Rodriguez, Miguel, Rozciecha, Jerzy, Ruiz Flores, Azalia Yuriria, Rydzewska, Grazyna, Safadi, Rifaat, Saibeni, Simone, Schirbel, Anja, Schmiegel, Wolff, Schnabel, Róbert, Schneider, Herbert, Segui, Armando, Seidelin, Jakob, Seidler, Ursula, Sellin, Joseph, Shafran, Ira, Shah, Saumin, Sheikh, Aasim, Sherman, Alex, Shirin, Haim, Shukla, Akash, Siddiqui, Firdous, Sike, Robert, Sood, Ajit, Stallmach, Andreas, Stanislavchuk, Mykola, Staun, Michael, Stein, Daniel, Steinberg, Alon, Steinhart, Hillary, Stifft, Jonathas, Tandon, Rakesh, Tantry, Vishwanath, Thiwan, Syed, Treiber, Matthias, Ulbrych, Jan, Valentine, John, Vasudeva, Rajeev, Vaughn, Byron, Velasco, Brenda, Vincze, Aron, Volfova, Miroslava, Waterman, Mattitiahu, Weiss, L. Michael, Wiesner, Elise, Williams, Alonzo, Witthoeft, Thomas, Wohlman, Robert, Wright, John, Yamamoto Furusho, Jesus Kazuo, Younes, Ziad, Yousuf, Khurshid, Zborivskyy, Yaroslav, Zeuzem, Stefan, Zhdan, Vyacheslav, Vermeire, Severine ^*, Lakatos, Peter L ^*, Kadva, Alysha, Tyrrell, Helen, Oh, Young S, Tole, Swati, Chai, Akiko, Pulley, Jennifer, Eden, Christopher, Zhang, Wenhui, Feagan, Brian G ^*

Publikováno v: In The Lancet Gastroenterology & Hepatology January 2022 7(1):28-37

Reduction of doxorubicine-induced senescence does not provide cardioprotective effect in mice

Autor: Goshovska, Yulia, Lazzarini, Edoardo, Rendon-Angel, Azucena, Biemmi, Vanessa, Colucci, Manuel, Alimonti, Andrea, Barile, Lucio

Publikováno v: In Vascular Pharmacology June 2024 155

Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging

Autor: Edoardo Lazzarini, Alessandra Maria Lodrini, Martina Arici, Sara Bolis, Sara Vagni, Stefano Panella, Azucena Rendon-Angel, Melissa Saibene, Alessia Metallo, Tiziano Torre, Giuseppe Vassalli, Pietro Ameri, Claudia Altomare, Marcella Rocchetti, Lucio Barile

Publikováno v: Theranostics. 12(11)

Rationale: Aging in the heart is a gradual process, involving continuous changes in cardiovascular cells, including cardiomyocytes (CMs), namely cellular senescence. These changes finally lead to adverse organ remodeling and resulting in heart failur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d62fd80707985323d3e9ddafcef3630
https://pubmed.ncbi.nlm.nih.gov/35836799

Protective role of cardiac progenitor cell-derived-exosomes in a new human model of ageing-induced cardiac dysfunction

Autor: E Lazzarini, AM Lodrini, S Bolis, M Arici, S Vagni, S Panella, A Rendon Angel, T Torre, G Vassalli, P Ameri, C Altomare, M Rocchetti, L Barile

Publikováno v: Cardiovascular Research. 118

Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Velux Stiftung Background Ageing of cardiomyocytes (CM) involves structural and functional adverse remodelling that finally could result in heart failure (HF) insur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc826b032a3e39121c9fd59dfeec96be
https://doi.org/10.1093/cvr/cvac066.011

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