Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Rende Gu"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Aminoglycosides (AG) antibiotics are a common treatment for recurrent infections in cystic fibrosis (CF) patients. AGs are highly ototoxic, resulting in a range of auditory dysfunctions. It was recently shown that the acoustic startle reflex (ASR) ca
Externí odkaz:
https://doaj.org/article/f3abf2117e274f3391e4e8c284aad1a1
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Aminoglycosides (AG) such as amikacin are commonly used in cystic fibrosis patients with opportunistic pulmonary infections including multi-drug resistant mycobacterium tuberculous and non-tuberculous mycobacterium. Unfortunately, this class of drugs
Externí odkaz:
https://doaj.org/article/4670d2050113403ab8d8e2a88795f8c2
Autor:
Juan C Maass, Rende Gu, Tiantian Cai, Ying-Wooi Wan, Silvia C Cantellano, Joanna S T Asprer, Hongyuan Zhang, Hsin-I Jen, Renée K Edlund, Zhandong Liu, Andrew K Groves
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167286 (2016)
Neonatal mouse cochlear supporting cells have a limited ability to divide and trans-differentiate into hair cells, but this ability declines rapidly in the two weeks after birth. This decline is concomitant with the morphological and functional matur
Externí odkaz:
https://doaj.org/article/ba681abddecc40ff923e417a0fa3bc6f
Publikováno v:
Journal of Cystic Fibrosis. 20:271-277
Background Cystic fibrosis patients are often adminstered tobramycin to treat pulmonary infections. Unfortunately, a common side effect is hearing loss, which can fluctuate. Ebselen has known anti-inflammatory properties and could reduce the incidenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697f9fa7d6455ee470795f5b7b69fbe7
https://doi.org/10.1016/j.jcf.2020.02.014
https://doi.org/10.1016/j.jcf.2020.02.014
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Aminoglycosides (AG) antibiotics are a common treatment for recurrent infections in cystic fibrosis (CF) patients. AGs are highly ototoxic, resulting in a range of auditory dysfunctions. It was recently shown that the acoustic startle reflex (ASR) ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93960f22dcf7d15b8d8d9781edc0b38
http://europepmc.org/articles/PMC8440845
http://europepmc.org/articles/PMC8440845
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 14 (2020)
Frontiers in Neuroscience, Vol 14 (2020)
Aminoglycosides (AG) such as amikacin are commonly used in cystic fibrosis patients with opportunistic pulmonary infections including multi-drug resistant mycobacterium tuberculous and non-tuberculous mycobacterium. Unfortunately, this class of drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6883c669cd0bc7934e1cc6770a7585c9
https://doi.org/10.3389/fnins.2020.561185
https://doi.org/10.3389/fnins.2020.561185
Autor:
Rende Gu, Tegy J. Vadakkan, Andrew K. Groves, Tiantian Cai, Mary E. Dickinson, Alyssa L. Crowder, Victor G. Piazza, Rogers M. Brown, Chih-Wei Hsu
Publikováno v:
Developmental Biology. 414:72-84
The transcription factor Sox2 is both necessary and sufficient for the generation of sensory regions of the inner ear. It regulates expression of the Notch ligand Jag1 in prosensory progenitors, which signal to neighboring cells to up-regulate Sox2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b6fcd461c4b71b9c42bf5a3df50280
https://doi.org/10.1016/j.ydbio.2016.03.027
https://doi.org/10.1016/j.ydbio.2016.03.027
Publikováno v:
European Journal of Medical Research, Vol 27, Iss 1, Pp 1-9 (2022)
Abstract Background Thyroid carcinoma (THCA) is the most prevalent type of tumor in endocrine system. NKD2 has been increasingly evidenced to play crucial roles in many cancers, except for THCA. We herein aimed to explore the potential role of NKD2 i
Externí odkaz:
https://doaj.org/article/22eab330875843e0baffccfde4dd64f1
Publikováno v:
The Open Otorhinolaryngology Journal. 5:25-34
Background: In mammals, sensory hair cells and supporting cells that comprise the auditory epithelium (i.e. organ of Corti) lose the ability to proliferate or regenerate after embryogenesis and are considered terminally differentiated. Previously, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94173ec0ba3e4ea8ec0c9b12f32b78de
https://doi.org/10.2174/1874428101105010025
https://doi.org/10.2174/1874428101105010025
Publikováno v:
European Journal of Neuroscience. 25:1363-1372
Millions of lives are affected by hearing and balance deficits that arise as a consequence of sensory hair cell loss. Those deficits affect mammals permanently, but hearing and balance recover in nonmammals after epithelial supporting cells divide an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8433cdd5bf151ffad4b04556052e61ff
https://doi.org/10.1111/j.1460-9568.2007.05414.x
https://doi.org/10.1111/j.1460-9568.2007.05414.x