Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Rendall R. Strawbridge"'
Autor:
Boyu Meng, Kenneth M. Tichauer, Kimberley S. Samkoe, Negar Sadeghipour, Margaret R. Folaron, Rendall R. Strawbridge, Scott C. Davis
Publikováno v:
Molecular Imaging and Biology
Purpose The ability to noninvasively quantify receptor availability (RA) in solid tumors is an aspirational goal of molecular imaging, often challenged by the influence of non-specific accumulation of the contrast agent. Paired-agent imaging (PAI) te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a59386f1c0507bf9faf2dd65047abf
https://doi.org/10.1007/s11307-021-01629-6
https://doi.org/10.1007/s11307-021-01629-6
Autor:
Negar Sadeghipour, Margaret R. Folaron, Scott C. Davis, Kimberley S. Samkoe, Boyu Meng, Rendall R. Strawbridge, Kenneth M. Tichauer
Publikováno v:
Theranostics
Immuno-oncological treatment strategies that target abnormal receptor profiles of tumors are an increasingly important feature of cancer therapy. Yet, assessing receptor availability (RA) and drug-target engagement, important determinants of therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18862cb67af7166d12324cbcc82189a0
https://doi.org/10.7150/thno.45273
https://doi.org/10.7150/thno.45273
Publikováno v:
Proceedings of SPIE--the International Society for Optical Engineering. 11219
MRI images of gadolinium-based contrast agents (GBCA's) acquired before surgery are often registered to patients and used to guide surgical resection of intracranial tumors. Yet, the accuracy of these MR images in describing the surgical field degrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4753b4fc532198f05ec3bb215b087490
https://pubmed.ncbi.nlm.nih.gov/34744247
https://pubmed.ncbi.nlm.nih.gov/34744247
Publikováno v:
Proc SPIE Int Soc Opt Eng
Concurrent administration of cancer therapeutics with tumor vasculature targeting treatment has been shown to improve overall survival in multiple human cancer types, as such combinations aim to destroy different compartments of tumors. Anti-angiogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec31c39e40e7fd1557adbf0e4217090
https://pubmed.ncbi.nlm.nih.gov/34446980
https://pubmed.ncbi.nlm.nih.gov/34446980
Publikováno v:
Proc SPIE Int Soc Opt Eng
Understanding the uptake and clearance kinetics of new drugs and contrast agents is an important aspect of drug development that typically involves a combination of imaging and analysis of harvested organs. Although these techniques are well-establis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5795c726e0d83826b160305282164caa
https://europepmc.org/articles/PMC8232864/
https://europepmc.org/articles/PMC8232864/
Autor:
Rendall R. Strawbridge, Margaret R. Folaron, Scott C. Davis, Negar Sadeghipour, Kimberley S. Samkoe, Aakanksha Rangnekar, Kenneth M. Tichauer
Publikováno v:
Journal of Biomedical Optics
Significance: Fluorescence guidance in cancer surgery (FGS) using molecular-targeted contrast agents is accelerating, yet the influence of individual patients’ physiology on the optimal time to perform surgery post-agent-injection is not fully unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08fcf39120f91ed5757aaf2911b1d64
https://pubmed.ncbi.nlm.nih.gov/33200596
https://pubmed.ncbi.nlm.nih.gov/33200596
Autor:
Scott C. Davis, Roshani A. Patil, Rendall R. Strawbridge, Brook K. Byrd, Mark Niedre, Jessica E. Fitzgerald, Chiara Bellini
Publikováno v:
Biomed Opt Express
Subcutaneous (s.c.) tumor models are widely used in pre-clinical cancer metastasis research. Despite this, the dynamics and natural progression of circulating tumor cells (CTCs) and CTC clusters (CTCCs) in peripheral blood are poorly understood in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcbf07d289f61a7bd98defc08b25a945
https://pubmed.ncbi.nlm.nih.gov/33014556
https://pubmed.ncbi.nlm.nih.gov/33014556
Publikováno v:
Proc SPIE Int Soc Opt Eng
Angiogenesis inhibiting cancer therapy has become a standard treatment for many cancer types. The ability to examine the effects of these drugs in tumors noninvasively could help assess efficacy early in the treatment course or identify optimal times
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2d8a798eef466cd0553de1560e89c2
https://doi.org/10.1117/12.2546702
https://doi.org/10.1117/12.2546702
Publikováno v:
Proc SPIE Int Soc Opt Eng
The ability to directly measure whole-body fluorescence can enable tracking of labeled cells, metastatic spread, and drug bio-distribution. We describe the development of a new hyperspectral imaging whole body cryo-macrotome designed to acquire 3-D f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1423ea8fa72b33376713693583f5e8a0
https://doi.org/10.1117/12.2544497
https://doi.org/10.1117/12.2544497
Autor:
Scott C. Davis, Kimberley S. Samkoe, Boyu Meng, Kenneth M. Tichauer, Margaret R. Folaron, Rendall R. Strawbridge
Publikováno v:
Proc SPIE Int Soc Opt Eng
Optical tomography is often coupled with high resolution imaging modality like MRI to provide functional information associated with specific anatomical structure noninvasively. MRI-coupled paired agent fluorescence molecular tomography (MRI-PAFT) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430046efa6aaa4ad86c49c2f498e8af3
https://doi.org/10.1117/12.2547083
https://doi.org/10.1117/12.2547083