Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Renchun Wang"'
Autor:
Jiacheng Lou, Yuchao Hao, Kefeng Lin, Yizhu Lyu, Meiwei Chen, Han Wang, Deyu Zou, Xuewen Jiang, Renchun Wang, Di Jin, Eric W.-F. Lam, Shujuan Shao, Quentin Liu, Jinsong Yan, Xiang Wang, Puxiang Chen, Bo Zhang, Bilian Jin
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-19 (2020)
Abstract Background Inactivation of the tumor suppressor p53 is critical for pathogenesis of glioma, in particular glioblastoma multiforme (GBM). MDM2, the main negative regulator of p53, binds to and forms a stable complex with p53 to regulate its a
Externí odkaz:
https://doaj.org/article/9a8bd3c14d3f414887b3d070b73c045d
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Herpes simplex encephalitis (HSE) caused by herpes simplex virus 1 (HSV-1) infection can lead to a high mortality rate and severe neurological sequelae. The destruction of the blood-brain barrier (BBB) is an important pathological mechanism for the d
Externí odkaz:
https://doaj.org/article/b7eacd40096247018c12f20f383e5f3b
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Background: Anti-N-methyl-D-aspartate receptor (NMDAR) immunoglobulin G antibodies which exist on myelin sheaths, composed of oligodendrocytes, especially target GluN1 subunits and are highly characteristic of anti-NMDAR encephalitis which is a newly
Externí odkaz:
https://doaj.org/article/e0257b97f526497ba6f48d047390bdee
Autor:
Han Zhang, Xizhi Deng, Yuxiu Zou, Xiangtian Ling, Renchun Wang, Hao Cheng, Xinqi Ma, Qingjiong Zhang, Huangxuan Shen, Jie Ning, Ping Zhang, Hao Huang, Han Tang, Shuibin Lin, Xielan Kuang, Chongde Long, Huijun Liu, Jianhua Yan, Han Du
Publikováno v:
Journal of Cellular and Molecular Medicine. 24:12368-12378
Retinoblastoma (RB) is a common intraocular malignancy in children. Due to the poor prognosis of RB, it is crucial to search for efficient diagnostic and therapeutic strategies. Studies have shown that methyltransferase-like 3 (METTL3), a major RNA N
Autor:
Jianhua Yan, Han Tang, Han Du, Xielan Kuang, Xinqi Ma, Jie Ning, Hao Huang, Xinyu Zhang, Qingjiong Zhang, Huijun Liu, Renchun Wang, Chongde Long, Han Zhang, Yuxiang Mao, Huangxuan Shen, Bing Xia
Publikováno v:
BioMed Research International, Vol 2020 (2020)
BioMed Research International
BioMed Research International
Background. Posterior capsule opacification (PCO), a complication of extracapsular lens extraction surgery that causes visual impairment, is characterized by aberrant proliferation and epithelial-mesenchymal transition (EMT) of lens epithelial cells
Autor:
Zixin Huang, Xinqi Ma, Qingjiong Zhang, Renchun Wang, Jie Ning, Huangxuan Shen, Yuxiang Mao, Chongde Long, Yu Liang, Yuting Fan, Qing Xia, Han Zhang, Shuibin Lin, Xielan Kuang
Publikováno v:
Journal of Cancer
Selective covalent CDK7 inhibitor THZ1 is a promising potential anti-tumor drug in many kinds of cancers. Epithelial-mesenchymal Transition (EMT) is highly related to cancer initiation, development, invasion and metastasis and other pathogenesis proc
Autor:
Puxiang Chen, Eric Lam, Meiwei Chen, Quentin Liu, Jia-Cheng Lou, Di Jin, Xuewen Jiang, Kefeng Lin, Deyu Zou, Hao Yuchao, Renchun Wang, Bo Zhang, Xiang Wang, Bilian Jin, Lyu Yizhu, Han Wang, Shujuan Shao, Jinsong Yan
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 19, Iss 1, Pp 1-19 (2020)
Molecular Cancer, Vol 19, Iss 1, Pp 1-19 (2020)
Background Inactivation of the tumor suppressor p53 is critical for pathogenesis of glioma, in particular glioblastoma multiforme (GBM). MDM2, the main negative regulator of p53, binds to and forms a stable complex with p53 to regulate its activity.
Autor:
Han, Zhang, Ping, Zhang, Chongde, Long, Xinqi, Ma, Hao, Huang, Xielan, Kuang, Han, Du, Han, Tang, Xiangtian, Ling, Jie, Ning, Huijun, Liu, Xizhi, Deng, Yuxiu, Zou, Renchun, Wang, Hao, Cheng, Shuibin, Lin, Qingjiong, Zhang, Jianhua, Yan, Huangxuan, Shen
Publikováno v:
Journal of Cellular and Molecular Medicine
Retinoblastoma (RB) is a common intraocular malignancy in children. Due to the poor prognosis of RB, it is crucial to search for efficient diagnostic and therapeutic strategies. Studies have shown that methyltransferase‐like 3 (METTL3), a major RNA
Autor:
Jiacheng Lou, Yuchao Hao, Kefeng Lin, Yizhu Lyu, Meiwei Chen, Wang, Han, Deyu Zou, Xuewen Jiang, Renchun Wang, Jin, Di, Lam, Eric W.-F., Shujuan Shao, Liu, Quentin, Jinsong Yan, Wang, Xiang, Puxiang Chen, Zhang, Bo, Jin, Bilian
Additional file 9 Figure S8. CDR1as serves as a protective machinery to preserve p53 function against DNA damage in LN229 cells. A. Western blot analysis of p53 and p21 expression (left), and RT-qPCR analysis of CDR1as expression (right) in LN229 cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722a68a1f657123a833151c1c4c17874
Autor:
Jiacheng Lou, Yuchao Hao, Kefeng Lin, Yizhu Lyu, Meiwei Chen, Wang, Han, Deyu Zou, Xuewen Jiang, Renchun Wang, Jin, Di, Lam, Eric W.-F., Shujuan Shao, Liu, Quentin, Jinsong Yan, Wang, Xiang, Puxiang Chen, Zhang, Bo, Jin, Bilian
Additional file 10 Figure S9. Ubiquitination of p53 in U87MG cells without MG132 treatment. A. Immunoblot of p53 ubiquitination in U87MG cells co-transfected with the plasmids encoding HA-Ub, Myc-MDM2 and CDR1as without MG132 treatment. B. Immunoblot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c93b3bdee25966c8420cc9edbc880b