Zobrazeno 1 - 10
of 281
pro vyhledávání: '"Renbing Jia"'
Autor:
Hanhan Shi, Hao Tian, Tianyu Zhu, Qili Liao, Chang Liu, Peng Yuan, Yongyun Li, Jie Yang, Chunyan Zong, Shichong Jia, Jing Ruan, Shengfang Ge, Renbing Jia, Peiwei Chai, Shiqiong Xu, Xianqun Fan
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Conjunctival melanoma (CoM) is a potentially devastating tumor that can lead to distant metastasis. Despite various therapeutic strategies for distant metastatic CoM, the clinical outcomes remain unfavorable. Herein, we performed single-cell
Externí odkaz:
https://doaj.org/article/308ff374b615437b9c05b694d34ef349
Autor:
Tianyu Zhu, Qian Li, Zhe Zhang, Jiahao Shi, Yongyun Li, Feng Zhang, Lingjie Li, Xin Song, Jianfeng Shen, Renbing Jia
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, is thought to play a significant role both in tumor suppression and tumor initiation, which is highly dependent upon context. Previous studies have suggested that ARID
Externí odkaz:
https://doaj.org/article/d2a37a9f071e4860b30d34cde1171454
Autor:
Lei Zhu, He Li, Xuening Peng, Zhaohuai Li, Sichen Zhao, Dongting Wu, Jialing Chen, Si Li, Renbing Jia, Zuohong Li, Wenru Su
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Background Dimethyl fumarate (DMF) is a fumaric acid ester that exhibits immunoregulatory and anti-inflammatory properties. However, the function of DMF in autoimmune uveitis (AU) is incompletely understood, and studies comprehensively explo
Externí odkaz:
https://doaj.org/article/c4a853a943bd40e4ae00bd3bd099c166
Autor:
Weihuan Shao, Yiran Yao, Ludi Yang, Xiaoran Li, Tongxin Ge, Yue Zheng, Qiuyi Zhu, Shengfang Ge, Xiang Gu, Renbing Jia, Xin Song, Ai Zhuang
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-34 (2024)
Abstract Adoptive immunotherapy in the T cell landscape exhibits efficacy in cancer treatment. Over the past few decades, genetically modified T cells, particularly chimeric antigen receptor T cells, have enabled remarkable strides in the treatment o
Externí odkaz:
https://doaj.org/article/219d03077d434ae9a374b1e021f3a27c
Autor:
Yongyun Li, Tianyu Zhu, Jie Yang, Qianqian Zhang, Shiqiong Xu, Shengfang Ge, Renbing Jia, Jianming Zhang, Xianqun Fan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1187-1203 (2024)
Constitutive activation of GNAQ/11 is the initiative oncogenic event in uveal melanoma (UM). Direct targeting GNAQ/11 has yet to be proven feasible as they are vital for a plethora of cellular functions. In search of genetic vulnerability for UM, we
Externí odkaz:
https://doaj.org/article/3eb653eb05ac41c1a5eceecc08536f44
Autor:
Yiran Yao, Ru Xu, Weihuan Shao, Ji Tan, Shaoyun Wang, Shuhan Chen, Ai Zhuang, Xuanyong Liu, Renbing Jia
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Uveal melanoma (UM) is a leading intraocular malignancy with a high 5‐year mortality rate, and radiotherapy is the primary approach for UM treatment. However, the elevated lactic acid, deficiency in ROS, and hypoxic tumor microenvironment
Externí odkaz:
https://doaj.org/article/058698dc47704b9d9cc61bab50250223
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-23 (2023)
Abstract Metabolic reprogramming of amino acids has been increasingly recognized to initiate and fuel tumorigenesis and survival. Therefore, there is emerging interest in the application of amino acid metabolic strategies in antitumor therapy. Tremen
Externí odkaz:
https://doaj.org/article/d2a8694cb1604e14bd5840b3560c931c
Autor:
Ai Zhuang, Xiang Gu, Tongxin Ge, Shaoyun Wang, Shengfang Ge, Peiwei Chai, Renbing Jia, Xianqun Fan
Publikováno v:
Cancer Communications, Vol 43, Iss 11, Pp 1185-1206 (2023)
Abstract Background Diversified histone deacetylation inhibitors (HDACis) have demonstrated encouraging outcomes in multiple malignancies. N6‐methyladenine (m6A) is the most prevalent messenger RNA modification that plays an essential role in the r
Externí odkaz:
https://doaj.org/article/4ac9993639d944488fddab79b4e4859c
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Metformin is a well-known anti-diabetic drug that has been repurposed for several emerging applications, including as an anti-cancer agent. It boasts the distinct advantages of an excellent safety and tolerability profile and high cost-effec
Externí odkaz:
https://doaj.org/article/2dc34a2e123f4ff5ba7c88e4e4189126
Autor:
Chunyan Zong, Zhe Zhang, Li Gao, Jie He, Yiran Wang, Qian Li, Xiaoting Liu, Jie Yang, Di Chen, Rui Huang, Guopei Zheng, Xiaoliang Jin, Wu Wei, Renbing Jia, Jianfeng Shen
Publikováno v:
Cell Death and Disease, Vol 14, Iss 6, Pp 1-12 (2023)
Abstract The cytidine deaminase, Apolipoprotein B mRNA editing enzyme catalytic subunit 3B (APOBEC3B, herein termed A3B), is a critical mutation driver that induces genomic instability in cancer by catalyzing cytosine-to-thymine (C-to-T) conversion a
Externí odkaz:
https://doaj.org/article/434ff5c602644aa5a48a95535d695cd3