Zobrazeno 1 - 10
of 282
pro vyhledávání: '"Renbing Jia"'
Publikováno v:
Holistic Integrative Oncology, Vol 3, Iss 1, Pp 1-13 (2024)
Abstract Retinoblastoma is the most common intraocular malignant tumor that poses a serious threat to the lives of children. Treatment plans for RB vary depending on the stage of the disease, and there is an uneven distribution of medical resources a
Externí odkaz:
https://doaj.org/article/874dadfc4bfa47d78a77acadc15787ec
Autor:
ChangJuan Zeng, Na Du, Liangyu He, Hui Wang, Ting Zhao, Renbing Jia, Lin Li, Minglei Han, Lili Hou
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Parents of children with retinoblastoma, the most common primary ocular malignant tumour in childhood, bear a heavy caregiving burden and are very susceptible to fatigue. However, little is known about their current status of fatigue and fac
Externí odkaz:
https://doaj.org/article/6ffa2791bfb94c0bb182d56c6b684394
Autor:
Hanhan Shi, Hao Tian, Tianyu Zhu, Qili Liao, Chang Liu, Peng Yuan, Yongyun Li, Jie Yang, Chunyan Zong, Shichong Jia, Jing Ruan, Shengfang Ge, Renbing Jia, Peiwei Chai, Shiqiong Xu, Xianqun Fan
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Conjunctival melanoma (CoM) is a potentially devastating tumor that can lead to distant metastasis. Despite various therapeutic strategies for distant metastatic CoM, the clinical outcomes remain unfavorable. Herein, we performed single-cell
Externí odkaz:
https://doaj.org/article/308ff374b615437b9c05b694d34ef349
Autor:
Tianyu Zhu, Qian Li, Zhe Zhang, Jiahao Shi, Yongyun Li, Feng Zhang, Lingjie Li, Xin Song, Jianfeng Shen, Renbing Jia
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background ARID1A, a subunit of the SWI/SNF chromatin remodeling complex, is thought to play a significant role both in tumor suppression and tumor initiation, which is highly dependent upon context. Previous studies have suggested that ARID
Externí odkaz:
https://doaj.org/article/d2a37a9f071e4860b30d34cde1171454
Autor:
Lei Zhu, He Li, Xuening Peng, Zhaohuai Li, Sichen Zhao, Dongting Wu, Jialing Chen, Si Li, Renbing Jia, Zuohong Li, Wenru Su
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Background Dimethyl fumarate (DMF) is a fumaric acid ester that exhibits immunoregulatory and anti-inflammatory properties. However, the function of DMF in autoimmune uveitis (AU) is incompletely understood, and studies comprehensively explo
Externí odkaz:
https://doaj.org/article/c4a853a943bd40e4ae00bd3bd099c166
Autor:
Weihuan Shao, Yiran Yao, Ludi Yang, Xiaoran Li, Tongxin Ge, Yue Zheng, Qiuyi Zhu, Shengfang Ge, Xiang Gu, Renbing Jia, Xin Song, Ai Zhuang
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-34 (2024)
Abstract Adoptive immunotherapy in the T cell landscape exhibits efficacy in cancer treatment. Over the past few decades, genetically modified T cells, particularly chimeric antigen receptor T cells, have enabled remarkable strides in the treatment o
Externí odkaz:
https://doaj.org/article/219d03077d434ae9a374b1e021f3a27c
Autor:
Liang Ma, Jie Yu, Yidian Fu, Xiaoyu He, Shengfang Ge, Renbing Jia, Ai Zhuang, Zhi Yang, Xianqun Fan
Publikováno v:
MedComm, Vol 5, Iss 9, Pp n/a-n/a (2024)
Abstract Cellular senescence, one of the hallmarks of cancer, is characterized by cell cycle arrest and the loss of most normal cellular functions while acquiring a hypersecretory, proinflammatory phenotype. The function of senescent cells in cancer
Externí odkaz:
https://doaj.org/article/5eee344a33a245aa9270e4d2012a1c15
Autor:
Yiran Yao, Ru Xu, Weihuan Shao, Ji Tan, Shaoyun Wang, Shuhan Chen, Ai Zhuang, Xuanyong Liu, Renbing Jia
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Uveal melanoma (UM) is a leading intraocular malignancy with a high 5‐year mortality rate, and radiotherapy is the primary approach for UM treatment. However, the elevated lactic acid, deficiency in ROS, and hypoxic tumor microenvironment
Externí odkaz:
https://doaj.org/article/058698dc47704b9d9cc61bab50250223
Autor:
Yongyun Li, Tianyu Zhu, Jie Yang, Qianqian Zhang, Shiqiong Xu, Shengfang Ge, Renbing Jia, Jianming Zhang, Xianqun Fan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1187-1203 (2024)
Constitutive activation of GNAQ/11 is the initiative oncogenic event in uveal melanoma (UM). Direct targeting GNAQ/11 has yet to be proven feasible as they are vital for a plethora of cellular functions. In search of genetic vulnerability for UM, we
Externí odkaz:
https://doaj.org/article/3eb653eb05ac41c1a5eceecc08536f44
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-23 (2023)
Abstract Metabolic reprogramming of amino acids has been increasingly recognized to initiate and fuel tumorigenesis and survival. Therefore, there is emerging interest in the application of amino acid metabolic strategies in antitumor therapy. Tremen
Externí odkaz:
https://doaj.org/article/d2a8694cb1604e14bd5840b3560c931c