Výsledky vyhledávání - "Renaud T Perchey"

Akademický článek

p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway

Autor: Pauline Jeannot, Ada Nowosad, Renaud T Perchey, Caroline Callot, Evangeline Bennana, Takanori Katsube, Patrick Mayeux, François Guillonneau, Stéphane Manenti, Arnaud Besson

Publikováno v: eLife, Vol 6 (2017)

p27Kip1 (p27) is a cyclin-CDK inhibitor and negative regulator of cell proliferation. p27 also controls other cellular processes including migration and cytoplasmic p27 can act as an oncogene. Furthermore, cytoplasmic p27 promotes invasion and metast

Externí odkaz: https://doaj.org/article/37a08fddd7294cc1a8109c4770f88350

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p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy–lysosomal pathway and coordinate cell cycle and cell growth

Autor: Ada Nowosad, Caroline Callot, Carine Joffre, Arnaud Besson, Stéphane Manenti, Patrice Codogno, Pauline Jeannot, Justine Creff, Renaud T. Perchey

Publikováno v: Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2020, 22 (9), pp.1076-1090. ⟨10.1038/s41556-020-0554-4⟩

International audience; Autophagy is a catabolic process whereby cytoplasmic components are degraded within lysosomes, allowing cells to maintain energy homeostasis during nutrient depletion. Several studies reported that the CDK inhibitor p27Kip1 pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94e1a946c85d0a3567d7dd5c51cec58
https://hal.archives-ouvertes.fr/hal-02989025

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p27 regulates the autophagy-lysosomal pathway via the control of Ragulator and mTOR activity in amino acid deprived cells

Autor: Pauline Jeannot, Patrice Codogno, Renaud T Perchey, Arnaud Besson, Stéphane Manenti, Caroline Callot, Ada Nowosad, Justine Creff, Carine Joffre

SummaryAutophagy is a catabolic process whereby cytoplasmic components are degraded within lysosomes, allowing cells to maintain energy homeostasis during nutrient depletion. Several studies have shown that the CDK inhibitor p27Kip1promotes starvatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a103e2742034f23771b9b63aaa52f5

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p27Kip1 regulates the microtubule bundling activity of PRC1

Autor: Renaud T. Perchey, Murielle P. Serres, Ada Nowosad, Justine Creff, Caroline Callot, Alexandre Gay, Stéphane Manenti, Robert L. Margolis, Anastassia Hatzoglou, Arnaud Besson

Publikováno v: Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 2018, 1865 (11), pp.1630-1639. ⟨10.1016/j.bbamcr.2018.08.010⟩
Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2018, 1865 (11), pp.1630-1639. ⟨10.1016/j.bbamcr.2018.08.010⟩

International audience; Cytokinesis begins in anaphase with the formation of the central spindle. PRC1 is a microtubule associated protein that plays an essential role in central spindle formation by crosslinking antiparallel microtubules. We have id

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307cb1055912caf0bbedee5c37cab2ae
https://doi.org/10.1016/j.bbamcr.2018.08.010

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Publisher Correction: p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy–lysosomal pathway and coordinate cell cycle and cell growth

Autor: Patrice Codogno, Caroline Callot, Justine Creff, Renaud T. Perchey, Stéphane Manenti, Pauline Jeannot, Carine Joffre, Ada Nowosad, Arnaud Besson

Publikováno v: Nature Cell Biology. 23:1048-1048

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84ab8eabe912ecac0751ffbf0afe5a3c
https://doi.org/10.1038/s41556-021-00741-7

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PTMselect: optimization of protein modifications discovery by mass spectrometry

Autor: Frédéric Lopez, Frédéric Pont, Arnaud Besson, Marie Tosolini, Laure Tonini, Jean-Jacques Fournié, Renaud T. Perchey

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.4181. ⟨10.1038/s41598-019-40873-3⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-40873-3⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)

Discovery of protein modification sites relies on protein digestion by proteases and mass spectrometry (MS) identification of the modified peptides. Depending on proteases used and target protein sequence, this method yields highly variable coverage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e641e6a7ea13563d9aaa116483cfe4b
https://doi.org/10.1038/s41598-019-40873-3

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Eph-mediated tyrosine phosphorylation of citron kinase controls abscission

Autor: Odile Burlet-Schiltz, Renaud T. Perchey, Carine Froment, Thomas Jungas, Arnaud Besson, Caroline Callot, Alice Davy, Mohamad Fawal

Publikováno v: The Journal of Cell Biology

Abscission is the last step of cytokinesis, allowing the physical separation of daughter cells at the end of cell division. It has been considered a cell autonomous process, yet Jungas et al. report that Ephrin/Eph signaling controls the completion o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a48ffe4601e588f90675735ee8ab8e
https://doi.org/10.1083/jcb.201602057

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p27

Autor: Renaud T, Perchey, Murielle P, Serres, Ada, Nowosad, Justine, Creff, Caroline, Callot, Alexandre, Gay, Stéphane, Manenti, Robert L, Margolis, Anastassia, Hatzoglou, Arnaud, Besson

Publikováno v: Biochimica et biophysica acta. Molecular cell research. 1865(11 Pt)

Cytokinesis begins in anaphase with the formation of the central spindle. PRC1 is a microtubule associated protein that plays an essential role in central spindle formation by crosslinking antiparallel microtubules. We have identified PRC1 as a novel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a9b7fc4c98a25fd93350a3057303815
https://pubmed.ncbi.nlm.nih.gov/30327204

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