Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Renaud Prudent"'
Autor:
Alaa Al Assi, Solène Posty, Frédéric Lamarche, Amel Chebel, Jérôme Guitton, Cécile Cottet-Rousselle, Renaud Prudent, Laurence Lafanechère, Stéphane Giraud, Patrick Dallemagne, Peggy Suzanne, Aurélie Verney, Laurent Genestier, Marie Castets, Eric Fontaine, Marc Billaud, Martine Cordier-Bussat
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-14 (2024)
Abstract Cancer cells are highly dependent on bioenergetic processes to support their growth and survival. Disruption of metabolic pathways, particularly by targeting the mitochondrial electron transport chain complexes (ETC-I to V) has become an att
Externí odkaz:
https://doaj.org/article/3280099ad7854690b1351796393f9c52
Autor:
Anne E. Mercier, Renaud Prudent, Michael S. Pepper, Leanne De Koning, Elsie Nolte, Lauralie Peronne, Marcel Nel, Laurence Lafanechère, Anna M. Joubert
Publikováno v:
Molecules, Vol 26, Iss 3, p 706 (2021)
The search for novel anti-cancer compounds which can circumvent chemotherapeutic drug resistance and limit systemic toxicity remains a priority. 2-Ethyl-3-O-sulphamoyl-estra-1,3,5(10)15-tetraene-3-ol-17one (ESE-15-one) and 2-ethyl-3-O-sulphamoyl-estr
Externí odkaz:
https://doaj.org/article/01728ee26385460c91981320dc8a7c59
Autor:
Renaud Prudent, Nathalie Demoncheaux, Hélène Diemer, Véronique Collin-Faure, Reuben Kapur, Fabrice Paublant, Laurence Lafanechère, Sarah Cianférani, Thierry Rabilloud
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208979 (2018)
LIM kinases are located at a strategic crossroad, downstream of several signaling pathways and upstream of effectors such as microtubules and the actin cytoskeleton. Cofilin is the only LIM kinases substrate that is well described to date, and its ph
Externí odkaz:
https://doaj.org/article/66ab9b0c9287423591288203f118f95c
Autor:
Emmanuelle Soleilhac, Loraine Brillet-Guéguen, Véronique Roussel, Renaud Prudent, Bastien Touquet, Sheena Dass, Samia Aci-Sèche, Vinod Kasam, Caroline Barette, Anne Imberty, Vincent Breton, Marylin Vantard, Dragos Horvath, Cyrille Botté, Isabelle Tardieux, Sylvaine Roy, Eric Maréchal, Laurence Lafanechère
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3085 (2018)
Dinitroanilines are chemical compounds with high selectivity for plant cell α-tubulin in which they promote microtubule depolymerization. They target α-tubulin regions that have diverged over evolution and show no effect on non-photosynthetic eukar
Externí odkaz:
https://doaj.org/article/789a13bed3834bf68035d3301dfb0715
Autor:
Michelle Visagie, Anne Theron, Thandi Mqoco, Warren Vieira, Renaud Prudent, Anne Martinez, Laurence Lafanechère, Annie Joubert
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e71935 (2013)
2-Methoxyestradiol (2ME2) is a naturally occurring estradiol metabolite which possesses antiproliferative, antiangiogenic and antitumor properties. However, due to its limited biological accessibility, synthetic analogues have been synthesized and te
Externí odkaz:
https://doaj.org/article/0d4768f1db5c42ceaeca946fa5dc627b
Autor:
Adrian Krzyzanowski, Lea Marie Esser, Anthony Willaume, Renaud Prudent, Christoph Peter, Peter ‘t Hart, Herbert Waldmann
Publikováno v:
Journal of Medicinal Chemistry. 65:15300-15311
The PRMT5-MEP50 methyltransferase is a major target for anticancer drug discovery, and modulators of its interactions with different regulatory proteins are in high demand because they modulate PRMT5 substrate selectivity. We describe a strategy for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aacaa84e715f5e991bde1398b5768b9a
https://doi.org/10.1021/acs.jmedchem.2c01273
https://doi.org/10.1021/acs.jmedchem.2c01273
Autor:
Laurence Lafanechère, Marc Billaud, Jacco van Rheenen, Jean-Luc Coll, Corinne Albiges-Rizo, Pascale A. Cohen, Reuben Kapur, Leanne de Koning, Renaud Prudent, Amandine Hurbin, Christopher Montemagno, Olivier Destaing, Christos Petropoulos, Evelyne Beerling, Julien Vollaire, Véronique Josserand, Chloé Prunier
MDA-MB-231 Dendra2 tumors followed by intravital microscopy after 8 days of Pyr1 treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de2ca29503ac7b5f1b88a50e7ee8f2d
https://doi.org/10.1158/0008-5472.22406879.v1
https://doi.org/10.1158/0008-5472.22406879.v1
Autor:
Laurence Lafanechère, Marc Billaud, Jacco van Rheenen, Jean-Luc Coll, Corinne Albiges-Rizo, Pascale A. Cohen, Reuben Kapur, Leanne de Koning, Renaud Prudent, Amandine Hurbin, Christopher Montemagno, Olivier Destaing, Christos Petropoulos, Evelyne Beerling, Julien Vollaire, Véronique Josserand, Chloé Prunier
RPPA results of tubulin acetylation, tubulin detyrosination and cofilin phosphorylation levels in tumors of mice treated with vehicle, Pyr1 and PTX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e7deb54a5dbbc0cfb28fe4d4b58feb
https://doi.org/10.1158/0008-5472.22406897
https://doi.org/10.1158/0008-5472.22406897
Autor:
Laurence Lafanechère, Marc Billaud, Jacco van Rheenen, Jean-Luc Coll, Corinne Albiges-Rizo, Pascale A. Cohen, Reuben Kapur, Leanne de Koning, Renaud Prudent, Amandine Hurbin, Christopher Montemagno, Olivier Destaing, Christos Petropoulos, Evelyne Beerling, Julien Vollaire, Véronique Josserand, Chloé Prunier
LIM kinases (LIMK) are emerging targets for cancer therapy, and they function as network hubs to coordinate actin and microtubule dynamics. When LIMKs are inhibited, actin microfilaments are disorganized and microtubules are stabilized. Owing to thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db98c922f7c9ee3b589b0f800f873bd
https://doi.org/10.1158/0008-5472.c.6507176.v1
https://doi.org/10.1158/0008-5472.c.6507176.v1
Autor:
Laurence Lafanechère, Marc Billaud, Jacco van Rheenen, Jean-Luc Coll, Corinne Albiges-Rizo, Pascale A. Cohen, Reuben Kapur, Leanne de Koning, Renaud Prudent, Amandine Hurbin, Christopher Montemagno, Olivier Destaing, Christos Petropoulos, Evelyne Beerling, Julien Vollaire, Véronique Josserand, Chloé Prunier
Effect of PTX on the viability of breast cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47fe347e2e4222984dd0c5ae0c25de53
https://doi.org/10.1158/0008-5472.22406906.v1
https://doi.org/10.1158/0008-5472.22406906.v1