Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Renaud Poincloux"'
Autor:
Reena Kumari, Katharina Ven, Megan Chastney, Shrikant B. Kokate, Johan Peränen, Jesse Aaron, Konstantin Kogan, Leonardo Almeida-Souza, Elena Kremneva, Renaud Poincloux, Teng-Leong Chew, Peter W. Gunning, Johanna Ivaska, Pekka Lappalainen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Focal adhesions (FAs) connect inner workings of cell to the extracellular matrix to control cell adhesion, migration and mechanosensing. Previous studies demonstrated that FAs contain three vertical layers, which connect extracellular matrix
Externí odkaz:
https://doaj.org/article/52ca205f2286428288ed7a744d2eb902
Autor:
Javier Rey-Barroso, Alice Munaretto, Nelly Rouquié, Aurélie Mougel, Malika Chassan, Sébastien Gadat, Océane Dewingle, Renaud Poincloux, Sarah Cadot, Loïc Ysebaert, Anne Quillet-Mary, Loïc Dupré
Publikováno v:
Haematologica, Vol 109, Iss 3 (2023)
The Bruton tyrosine kinase (BTK) inhibitor ibrutinib is widely used for treatment of patients with relapsed/refractory or treatment-naïve chronic lymphocytic leukemia (CLL). A prominent effect of ibrutinib is to disrupt the retention of CLL cells fr
Externí odkaz:
https://doaj.org/article/29c100f1121c45a9b80d70916791602f
Autor:
Marion Jasnin, Jordan Hervy, Stéphanie Balor, Anaïs Bouissou, Amsha Proag, Raphaël Voituriez, Jonathan Schneider, Thomas Mangeat, Isabelle Maridonneau-Parini, Wolfgang Baumeister, Serge Dmitrieff, Renaud Poincloux
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Actin filaments generate force in diverse contexts, although how they can produce nanonewtons of force is unclear. Here, the authors apply cryo-electron tomography, quantitative analysis, and modelling to reveal the podosome core is a dense, spring-l
Externí odkaz:
https://doaj.org/article/6a755f77948444fda10cc78808a00945
Autor:
Karin Santoni, David Pericat, Leana Gorse, Julien Buyck, Miriam Pinilla, Laure Prouvensier, Salimata Bagayoko, Audrey Hessel, Stephen Adonai Leon-Icaza, Elisabeth Bellard, Serge Mazères, Emilie Doz-Deblauwe, Nathalie Winter, Christophe Paget, Jean-Philippe Girard, Christine T N Pham, Céline Cougoule, Renaud Poincloux, Mohamed Lamkanfi, Emma Lefrançais, Etienne Meunier, Rémi Planès
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010305 (2022)
Multiple regulated neutrophil cell death programs contribute to host defense against infections. However, despite expressing all necessary inflammasome components, neutrophils are thought to be generally defective in Caspase-1-dependent pyroptosis. B
Externí odkaz:
https://doaj.org/article/3c1e9945786845ad89fa25728c4ad6f4
Autor:
Marion Portes, Thomas Mangeat, Natacha Escallier, Ophélie Dufrancais, Brigitte Raynaud-Messina, Christophe Thibault, Isabelle Maridonneau-Parini, Christel Vérollet, Renaud Poincloux
Publikováno v:
eLife, Vol 11 (2022)
Osteoclasts are unique in their capacity to degrade bone tissue. To achieve this process, osteoclasts form a specific structure called the sealing zone, which creates a close contact with bone and confines the release of protons and hydrolases for bo
Externí odkaz:
https://doaj.org/article/d02836c2d9c243a7a4858cf48e5f9b0a
Autor:
Margot Tertrais, Claire Bigot, Emmanuel Martin, Renaud Poincloux, Arnaud Labrousse, Isabelle Maridonneau-Parini
Publikováno v:
European Journal of Cell Biology, Vol 100, Iss 4, Pp 151161- (2021)
Phagocytosis consists in ingestion and digestion of large particles, a process strictly dependent on actin re-organization. Using synchronized phagocytosis of IgG-coated latex beads (IgG-LB), zymosan or serum opsonized-zymosan, we report the formatio
Externí odkaz:
https://doaj.org/article/82c9098c9bb14c22864d3f47c9f6226d
Autor:
Thomas Mangeat, Simon Labouesse, Marc Allain, Awoke Negash, Emmanuel Martin, Aude Guénolé, Renaud Poincloux, Claire Estibal, Anaïs Bouissou, Sylvain Cantaloube, Elodie Vega, Tong Li, Christian Rouvière, Sophie Allart, Debora Keller, Valentin Debarnot, Xia Bo Wang, Grégoire Michaux, Mathieu Pinot, Roland Le Borgne, Sylvie Tournier, Magali Suzanne, Jérome Idier, Anne Sentenac
Publikováno v:
Cell Reports: Methods, Vol 1, Iss 1, Pp 100009- (2021)
Summary: Current super-resolution microscopy (SRM) methods suffer from an intrinsic complexity that might curtail their routine use in cell biology. We describe here random illumination microscopy (RIM) for live-cell imaging at super-resolutions matc
Externí odkaz:
https://doaj.org/article/b7ddc3df410e4b26b598a7b09dc81564
Autor:
Maeva Dupont, Shanti Souriant, Luciana Balboa, Thien-Phong Vu Manh, Karine Pingris, Stella Rousset, Céline Cougoule, Yoann Rombouts, Renaud Poincloux, Myriam Ben Neji, Carolina Allers, Deepak Kaushal, Marcelo J Kuroda, Susana Benet, Javier Martinez-Picado, Nuria Izquierdo-Useros, Maria del Carmen Sasiain, Isabelle Maridonneau-Parini, Olivier Neyrolles, Christel Vérollet, Geanncarlo Lugo-Villarino
Publikováno v:
eLife, Vol 9 (2020)
While tuberculosis (TB) is a risk factor in HIV-1-infected individuals, the mechanisms by which Mycobacterium tuberculosis (Mtb) worsens HIV-1 pathogenesis remain scarce. We showed that HIV-1 infection is exacerbated in macrophages exposed to TB-asso
Externí odkaz:
https://doaj.org/article/6af16a7012534a289b8f47da025dddeb
Autor:
Francesco Baschieri, Stéphane Dayot, Nadia Elkhatib, Nathalie Ly, Anahi Capmany, Kristine Schauer, Timo Betz, Danijela Matic Vignjevic, Renaud Poincloux, Guillaume Montagnac
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Cells sense mechanical properties of their environment using various cellular structures including focal adhesions. Here, the authors identify flat clathrin-coated structures (CCSs) as mechanosensitive signaling platforms that form independently of c
Externí odkaz:
https://doaj.org/article/7c868a476ff541acbb2290819e5e83b7
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
The actomyosin cytoskeleton plays an important role in polarised cell migration. Here the authors identify lymphocyte-specific protein (LSP)-1 as a regulator of actomyosin contractility in macrophages, by competing with supervillin for myosin IIA act
Externí odkaz:
https://doaj.org/article/f3f5c58257864c0498c0aecf08fa9c52